Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9FHL

High-resolution cryo-EM structure of Saccharolobus solfataricus 30S ribosomal subunit bound to mRNA and initiator tRNA

Functional Information from GO Data

Chain	GOid	namespace	contents
3	0001682	biological_process	tRNA 5'-leader removal
3	0003723	molecular_function	RNA binding
3	0003735	molecular_function	structural constituent of ribosome
3	0004526	molecular_function	ribonuclease P activity
3	0005737	cellular_component	cytoplasm
3	0005840	cellular_component	ribosome
3	0006412	biological_process	translation
3	0042254	biological_process	ribosome biogenesis
3	1990904	cellular_component	ribonucleoprotein complex
a	0005737	cellular_component	cytoplasm
A	0003735	molecular_function	structural constituent of ribosome
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005840	cellular_component	ribosome
A	0006412	biological_process	translation
B	0000028	biological_process	ribosomal small subunit assembly
B	0003735	molecular_function	structural constituent of ribosome
B	0005737	cellular_component	cytoplasm
B	0005840	cellular_component	ribosome
B	0006412	biological_process	translation
B	0015935	cellular_component	small ribosomal subunit
B	0022627	cellular_component	cytosolic small ribosomal subunit
c	0005737	cellular_component	cytoplasm
c	0022627	cellular_component	cytosolic small ribosomal subunit
C	0005737	cellular_component	cytoplasm
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005737	cellular_component	cytoplasm
D	0006412	biological_process	translation
D	0015935	cellular_component	small ribosomal subunit
D	0019843	molecular_function	rRNA binding
D	0042274	biological_process	ribosomal small subunit biogenesis
D	0043226	cellular_component	organelle
e	0003735	molecular_function	structural constituent of ribosome
e	0005737	cellular_component	cytoplasm
e	0005840	cellular_component	ribosome
e	0006412	biological_process	translation
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005737	cellular_component	cytoplasm
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0022627	cellular_component	cytosolic small ribosomal subunit
F	0003723	molecular_function	RNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005737	cellular_component	cytoplasm
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0015935	cellular_component	small ribosomal subunit
F	0019843	molecular_function	rRNA binding
F	0022627	cellular_component	cytosolic small ribosomal subunit
G	0003735	molecular_function	structural constituent of ribosome
G	0005737	cellular_component	cytoplasm
G	0005840	cellular_component	ribosome
G	0006412	biological_process	translation
H	0003723	molecular_function	RNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005737	cellular_component	cytoplasm
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0015935	cellular_component	small ribosomal subunit
H	0019843	molecular_function	rRNA binding
H	0022627	cellular_component	cytosolic small ribosomal subunit
I	0003735	molecular_function	structural constituent of ribosome
I	0005737	cellular_component	cytoplasm
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0019843	molecular_function	rRNA binding
I	0022627	cellular_component	cytosolic small ribosomal subunit
J	0002181	biological_process	cytoplasmic translation
J	0003735	molecular_function	structural constituent of ribosome
J	0005737	cellular_component	cytoplasm
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0022627	cellular_component	cytosolic small ribosomal subunit
K	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K	0003735	molecular_function	structural constituent of ribosome
K	0005737	cellular_component	cytoplasm
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0022627	cellular_component	cytosolic small ribosomal subunit
L	0000049	molecular_function	tRNA binding
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005737	cellular_component	cytoplasm
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0015935	cellular_component	small ribosomal subunit
L	0022627	cellular_component	cytosolic small ribosomal subunit
M	0003735	molecular_function	structural constituent of ribosome
M	0005737	cellular_component	cytoplasm
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0019843	molecular_function	rRNA binding
M	0022627	cellular_component	cytosolic small ribosomal subunit
N	0003735	molecular_function	structural constituent of ribosome
N	0005737	cellular_component	cytoplasm
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0015935	cellular_component	small ribosomal subunit
N	0019843	molecular_function	rRNA binding
N	0022627	cellular_component	cytosolic small ribosomal subunit
O	0003676	molecular_function	nucleic acid binding
O	0003723	molecular_function	RNA binding
O	0003735	molecular_function	structural constituent of ribosome
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0015935	cellular_component	small ribosomal subunit
O	0019843	molecular_function	rRNA binding
P	0002181	biological_process	cytoplasmic translation
P	0003723	molecular_function	RNA binding
P	0003735	molecular_function	structural constituent of ribosome
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0008270	molecular_function	zinc ion binding
P	0015935	cellular_component	small ribosomal subunit
P	0019843	molecular_function	rRNA binding
P	0022627	cellular_component	cytosolic small ribosomal subunit
Q	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005737	cellular_component	cytoplasm
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0022627	cellular_component	cytosolic small ribosomal subunit
R	0003735	molecular_function	structural constituent of ribosome
R	0005737	cellular_component	cytoplasm
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0019843	molecular_function	rRNA binding
R	0022627	cellular_component	cytosolic small ribosomal subunit
S	0003735	molecular_function	structural constituent of ribosome
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0015935	cellular_component	small ribosomal subunit
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005737	cellular_component	cytoplasm
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0015935	cellular_component	small ribosomal subunit
T	0019843	molecular_function	rRNA binding
T	0022627	cellular_component	cytosolic small ribosomal subunit
U	0003735	molecular_function	structural constituent of ribosome
U	0005737	cellular_component	cytoplasm
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0022627	cellular_component	cytosolic small ribosomal subunit
U	0030490	biological_process	maturation of SSU-rRNA
V	0002181	biological_process	cytoplasmic translation
V	0003735	molecular_function	structural constituent of ribosome
V	0005737	cellular_component	cytoplasm
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0015935	cellular_component	small ribosomal subunit
W	0003735	molecular_function	structural constituent of ribosome
W	0005737	cellular_component	cytoplasm
W	0005840	cellular_component	ribosome
W	0006364	biological_process	rRNA processing
W	0006412	biological_process	translation
W	0008270	molecular_function	zinc ion binding
W	0022627	cellular_component	cytosolic small ribosomal subunit
X	0000028	biological_process	ribosomal small subunit assembly
X	0003735	molecular_function	structural constituent of ribosome
X	0005737	cellular_component	cytoplasm
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0022627	cellular_component	cytosolic small ribosomal subunit
X	0030490	biological_process	maturation of SSU-rRNA
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005737	cellular_component	cytoplasm
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Y	0008270	molecular_function	zinc ion binding
Z	0003676	molecular_function	nucleic acid binding
Z	0003723	molecular_function	RNA binding
Z	0003735	molecular_function	structural constituent of ribosome
Z	0006412	biological_process	translation
Z	0015935	cellular_component	small ribosomal subunit
Z	0019843	molecular_function	rRNA binding
Z	0022626	cellular_component	cytosolic ribosome
Z	0022627	cellular_component	cytosolic small ribosomal subunit

Functional Information from PROSITE/UniProt

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLinqIMrpgrnkGKKhlaynIVklA

Chain	Residue	Details
H	GLU59-ALA85

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GiiIVSTSkGVMshkeAA

Chain	Residue	Details
I	GLY103-ALA120

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. IrALarA.GFiIgrieDvTPiPHD

Chain	Residue	Details
M	ILE97-ASP119

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. RqPNSAvR

Chain	Residue	Details
N	ARG63-ARG70

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDkViIgEcRPLS

Chain	Residue	Details
R	GLY90-SER102

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKefveftVtpemIGhyLGEYsiT

Chain	Residue	Details
T	ASN92-THR116

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGimGQadAarmAlARAL

Chain	Residue	Details
K	GLY72-LEU90

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. VektGIemrGPIpLPT

Chain	Residue	Details
L	VAL28-THR43

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. VrrHIneyPrDktAkkgLeeIeskirrLtrY

Chain	Residue	Details
Q	VAL96-TYR126

site_id	PS00527
Number of Residues	22
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. R.Cgskdsviqkyg.IYLCRqCFR

Chain	Residue	Details
P	ARG21-ARG42

site_id	PS00529
Number of Residues	23
Details	RIBOSOMAL_S24E Ribosomal protein S24e signature. YGagISnVKLhIYKSreilekvE

Chain	Residue	Details
V	TYR72-GLU94

site_id	PS00548
Number of Residues	37
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. ARyeklkeGiVykSgqqLekmIDraiaiamLkpGifG

Chain	Residue	Details
Z	ALA142-GLY178

site_id	PS00578
Number of Residues	12
Details	RIBOSOMAL_S6E Ribosomal protein S6e signature. ITGGsDnsGfPM

Chain	Residue	Details
G	ILE152-MET163

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GEisrYkVlvIMGNmd.GyVSiGtgkak.QLrv.AI

Chain	Residue	Details
F	GLY71-ILE103

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtiVYKkglSnTiyqARqLI

Chain	Residue	Details
D	LEU102-ILE126

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGvRHslGlkVRGQ

Chain	Residue	Details
O	ARG117-GLN130

site_id	PS00712
Number of Residues	16
Details	RIBOSOMAL_S17E Ribosomal protein S17e signature. VkSKkVRNrIAGYlTR

Chain	Residue	Details
S	VAL41-ARG56

site_id	PS00961
Number of Residues	9
Details	RIBOSOMAL_S28E Ribosomal protein S28e signature. ETEREARkI

Chain	Residue	Details
X	GLU70-ILE78

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VdTYLSAGVHIG

Chain	Residue	Details
B	VAL39-GLY50

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PkvLLVsDprtDtqaIkEaakvGIP

Chain	Residue	Details
B	PRO142-PRO166

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CdekkIPYvyVsSKkaLG

Chain	Residue	Details
3	CYS70-GLY87

site_id	PS01168
Number of Residues	33
Details	RIBOSOMAL_S27E Ribosomal protein S27e signature. KCpnCgneqtiFShAtfpvrClsCGteLvySmG

Chain	Residue	Details
W	LYS20-GLY52

site_id	PS01193
Number of Residues	20
Details	RIBOSOMAL_S8E Ribosomal protein S8e signature. RkiTGGlkgkh.RdKrKyEIG

Chain	Residue	Details
J	ARG10-GLY29

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	19
Details	Binding site: {"evidences":[{"source":"PDB","id":"9FHL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FRA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FRK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FRL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FS6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FS8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FSF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FY0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	62
Details	Domain: {"description":"S4 RNA-binding","evidences":[{"source":"HAMAP-Rule","id":"MF_00485","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	63
Details	Domain: {"description":"S5 DRBM","evidences":[{"source":"HAMAP-Rule","id":"MF_01307","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PDB","id":"9FHL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FRA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FRK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FS6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FS8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FSF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FY0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01364","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"9FHL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FRA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FRK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FRL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FS6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FS8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FSF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FY0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	22
Details	Zinc finger: {"description":"C4-type","evidences":[{"source":"HAMAP-Rule","id":"MF_00371","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00371","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"9FHL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FRA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FRK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FRL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FS6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FS8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FSF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FY0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00371","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"9FHL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FRA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FSF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00371","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"9FHL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FRA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FRK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FRL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FS6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FS8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FY0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	22
Details	Zinc finger: {"description":"C4-type","evidences":[{"source":"HAMAP-Rule","id":"MF_00777","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00777","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	69
Details	Domain: {"description":"KH type-2","evidences":[{"source":"HAMAP-Rule","id":"MF_01309","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PDB","id":"9FHL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FRA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FRL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FS6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FS8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FSF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9FY0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	25
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)