9FH0
Pex5-Eci1 complex - Pex5 local refinement
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004165 | molecular_function | delta(3)-delta(2)-enoyl-CoA isomerase activity |
| A | 0005777 | cellular_component | peroxisome |
| A | 0005782 | cellular_component | peroxisomal matrix |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006635 | biological_process | fatty acid beta-oxidation |
| A | 0016853 | molecular_function | isomerase activity |
| G | 0005052 | molecular_function | peroxisome matrix targeting signal-1 binding |
| G | 0005515 | molecular_function | protein binding |
| G | 0005777 | cellular_component | peroxisome |
| G | 0005778 | cellular_component | peroxisomal membrane |
| G | 0005782 | cellular_component | peroxisomal matrix |
| G | 0005829 | cellular_component | cytosol |
| G | 0015031 | biological_process | protein transport |
| G | 0016558 | biological_process | protein import into peroxisome matrix |
| G | 0016560 | biological_process | protein import into peroxisome matrix, docking |
| G | 0030674 | molecular_function | protein-macromolecule adaptor activity |
| G | 0140597 | molecular_function | protein carrier chaperone |
| G | 1990429 | cellular_component | peroxisomal importomer complex |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Motif: {"description":"Microbody targeting signal","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"26527136","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26527136","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4ZDB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZDC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26527136","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4ZDC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 33 |
| Details | Repeat: {"description":"TPR 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 33 |
| Details | Repeat: {"description":"TPR 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 37 |
| Details | Repeat: {"description":"TPR 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 33 |
| Details | Repeat: {"description":"TPR 6"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 33 |
| Details | Repeat: {"description":"TPR 7"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 33 |
| Details | Repeat: {"description":"TPR 8"} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 499 |
| Chain | Residue | Details |
| A | ALA70 | electrostatic stabiliser |
| A | ASN101 | electrostatic stabiliser, modifies pKa |
| A | LEU126 | electrostatic stabiliser |
| A | GLU158 | proton acceptor, proton donor |
