9F6Z

Human N-deacetylase/N-sulfotransferase 1 homodimer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0003824	molecular_function	catalytic activity
A	0005515	molecular_function	protein binding
A	0005794	cellular_component	Golgi apparatus
A	0006954	biological_process	inflammatory response
A	0008146	molecular_function	sulfotransferase activity
A	0015012	biological_process	heparan sulfate proteoglycan biosynthetic process
A	0015016	molecular_function	heparan sulfate N-sulfotransferase activity
A	0016740	molecular_function	transferase activity
A	0016787	molecular_function	hydrolase activity
A	0019213	molecular_function	deacetylase activity
A	0030210	biological_process	heparin proteoglycan biosynthetic process
A	0032588	cellular_component	trans-Golgi network membrane
A	0050119	molecular_function	N-acetylglucosamine deacetylase activity
A	0102140	molecular_function	heparan sulfate N-deacetylase activity
B	0000139	cellular_component	Golgi membrane
B	0003824	molecular_function	catalytic activity
B	0005515	molecular_function	protein binding
B	0005794	cellular_component	Golgi apparatus
B	0006954	biological_process	inflammatory response
B	0008146	molecular_function	sulfotransferase activity
B	0015012	biological_process	heparan sulfate proteoglycan biosynthetic process
B	0015016	molecular_function	heparan sulfate N-sulfotransferase activity
B	0016740	molecular_function	transferase activity
B	0016787	molecular_function	hydrolase activity
B	0019213	molecular_function	deacetylase activity
B	0030210	biological_process	heparin proteoglycan biosynthetic process
B	0032588	cellular_component	trans-Golgi network membrane
B	0050119	molecular_function	N-acetylglucosamine deacetylase activity
B	0102140	molecular_function	heparan sulfate N-deacetylase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	566
Details	Region: {"description":"Heparan sulfate N-sulfotransferase 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"For sulfotransferase activity","evidences":[{"source":"PubMed","id":"9744796","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10196134","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1NST","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---