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9F3R

13pf E254Q microtubule from recombinant human tubulin decorated with EB3

Functional Information from GO Data
ChainGOidnamespacecontents
B0000166molecular_functionnucleotide binding
B0000226biological_processmicrotubule cytoskeleton organization
B0000278biological_processmitotic cell cycle
B0005200molecular_functionstructural constituent of cytoskeleton
B0005515molecular_functionprotein binding
B0005525molecular_functionGTP binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005856cellular_componentcytoskeleton
B0005874cellular_componentmicrotubule
B0007411biological_processaxon guidance
B0015630cellular_componentmicrotubule cytoskeleton
B0030027cellular_componentlamellipodium
B0030175cellular_componentfilopodium
B0030182biological_processneuron differentiation
B0030424cellular_componentaxon
B0030425cellular_componentdendrite
B0030426cellular_componentgrowth cone
B0038007biological_processnetrin-activated signaling pathway
B0042277molecular_functionpeptide binding
B0042995cellular_componentcell projection
B0043025cellular_componentneuronal cell body
B0045171cellular_componentintercellular bridge
B0046872molecular_functionmetal ion binding
B0070062cellular_componentextracellular exosome
B0071944cellular_componentcell periphery
B0072686cellular_componentmitotic spindle
B1990791biological_processdorsal root ganglion development
B1990890molecular_functionnetrin receptor binding
D0000166molecular_functionnucleotide binding
D0000226biological_processmicrotubule cytoskeleton organization
D0000278biological_processmitotic cell cycle
D0005200molecular_functionstructural constituent of cytoskeleton
D0005515molecular_functionprotein binding
D0005525molecular_functionGTP binding
D0005634cellular_componentnucleus
D0005737cellular_componentcytoplasm
D0005856cellular_componentcytoskeleton
D0005874cellular_componentmicrotubule
D0007411biological_processaxon guidance
D0015630cellular_componentmicrotubule cytoskeleton
D0030027cellular_componentlamellipodium
D0030175cellular_componentfilopodium
D0030182biological_processneuron differentiation
D0030424cellular_componentaxon
D0030425cellular_componentdendrite
D0030426cellular_componentgrowth cone
D0038007biological_processnetrin-activated signaling pathway
D0042277molecular_functionpeptide binding
D0042995cellular_componentcell projection
D0043025cellular_componentneuronal cell body
D0045171cellular_componentintercellular bridge
D0046872molecular_functionmetal ion binding
D0070062cellular_componentextracellular exosome
D0071944cellular_componentcell periphery
D0072686cellular_componentmitotic spindle
D1990791biological_processdorsal root ganglion development
D1990890molecular_functionnetrin receptor binding
F0000166molecular_functionnucleotide binding
F0000226biological_processmicrotubule cytoskeleton organization
F0000278biological_processmitotic cell cycle
F0005200molecular_functionstructural constituent of cytoskeleton
F0005515molecular_functionprotein binding
F0005525molecular_functionGTP binding
F0005634cellular_componentnucleus
F0005737cellular_componentcytoplasm
F0005856cellular_componentcytoskeleton
F0005874cellular_componentmicrotubule
F0007411biological_processaxon guidance
F0015630cellular_componentmicrotubule cytoskeleton
F0030027cellular_componentlamellipodium
F0030175cellular_componentfilopodium
F0030182biological_processneuron differentiation
F0030424cellular_componentaxon
F0030425cellular_componentdendrite
F0030426cellular_componentgrowth cone
F0038007biological_processnetrin-activated signaling pathway
F0042277molecular_functionpeptide binding
F0042995cellular_componentcell projection
F0043025cellular_componentneuronal cell body
F0045171cellular_componentintercellular bridge
F0046872molecular_functionmetal ion binding
F0070062cellular_componentextracellular exosome
F0071944cellular_componentcell periphery
F0072686cellular_componentmitotic spindle
F1990791biological_processdorsal root ganglion development
F1990890molecular_functionnetrin receptor binding
N0000166molecular_functionnucleotide binding
N0000226biological_processmicrotubule cytoskeleton organization
N0000278biological_processmitotic cell cycle
N0005200molecular_functionstructural constituent of cytoskeleton
N0005515molecular_functionprotein binding
N0005525molecular_functionGTP binding
N0005634cellular_componentnucleus
N0005737cellular_componentcytoplasm
N0005856cellular_componentcytoskeleton
N0005874cellular_componentmicrotubule
N0007411biological_processaxon guidance
N0015630cellular_componentmicrotubule cytoskeleton
N0030027cellular_componentlamellipodium
N0030175cellular_componentfilopodium
N0030182biological_processneuron differentiation
N0030424cellular_componentaxon
N0030425cellular_componentdendrite
N0030426cellular_componentgrowth cone
N0038007biological_processnetrin-activated signaling pathway
N0042277molecular_functionpeptide binding
N0042995cellular_componentcell projection
N0043025cellular_componentneuronal cell body
N0045171cellular_componentintercellular bridge
N0046872molecular_functionmetal ion binding
N0070062cellular_componentextracellular exosome
N0071944cellular_componentcell periphery
N0072686cellular_componentmitotic spindle
N1990791biological_processdorsal root ganglion development
N1990890molecular_functionnetrin receptor binding
P0000166molecular_functionnucleotide binding
P0000226biological_processmicrotubule cytoskeleton organization
P0000278biological_processmitotic cell cycle
P0005200molecular_functionstructural constituent of cytoskeleton
P0005515molecular_functionprotein binding
P0005525molecular_functionGTP binding
P0005634cellular_componentnucleus
P0005737cellular_componentcytoplasm
P0005856cellular_componentcytoskeleton
P0005874cellular_componentmicrotubule
P0007411biological_processaxon guidance
P0015630cellular_componentmicrotubule cytoskeleton
P0030027cellular_componentlamellipodium
P0030175cellular_componentfilopodium
P0030182biological_processneuron differentiation
P0030424cellular_componentaxon
P0030425cellular_componentdendrite
P0030426cellular_componentgrowth cone
P0038007biological_processnetrin-activated signaling pathway
P0042277molecular_functionpeptide binding
P0042995cellular_componentcell projection
P0043025cellular_componentneuronal cell body
P0045171cellular_componentintercellular bridge
P0046872molecular_functionmetal ion binding
P0070062cellular_componentextracellular exosome
P0071944cellular_componentcell periphery
P0072686cellular_componentmitotic spindle
P1990791biological_processdorsal root ganglion development
P1990890molecular_functionnetrin receptor binding
R0000166molecular_functionnucleotide binding
R0000226biological_processmicrotubule cytoskeleton organization
R0000278biological_processmitotic cell cycle
R0005200molecular_functionstructural constituent of cytoskeleton
R0005515molecular_functionprotein binding
R0005525molecular_functionGTP binding
R0005634cellular_componentnucleus
R0005737cellular_componentcytoplasm
R0005856cellular_componentcytoskeleton
R0005874cellular_componentmicrotubule
R0007411biological_processaxon guidance
R0015630cellular_componentmicrotubule cytoskeleton
R0030027cellular_componentlamellipodium
R0030175cellular_componentfilopodium
R0030182biological_processneuron differentiation
R0030424cellular_componentaxon
R0030425cellular_componentdendrite
R0030426cellular_componentgrowth cone
R0038007biological_processnetrin-activated signaling pathway
R0042277molecular_functionpeptide binding
R0042995cellular_componentcell projection
R0043025cellular_componentneuronal cell body
R0045171cellular_componentintercellular bridge
R0046872molecular_functionmetal ion binding
R0070062cellular_componentextracellular exosome
R0071944cellular_componentcell periphery
R0072686cellular_componentmitotic spindle
R1990791biological_processdorsal root ganglion development
R1990890molecular_functionnetrin receptor binding
Functional Information from PROSITE/UniProt
site_idPS00227
Number of Residues7
DetailsTUBULIN Tubulin subunits alpha, beta, and gamma signature. GGGTGSG
ChainResidueDetails
BGLY140-GLY146
AGLY142-GLY148

site_idPS00228
Number of Residues4
DetailsTUBULIN_B_AUTOREG Tubulin-beta mRNA autoregulation signal. MREI
ChainResidueDetails
BMET1-ILE4

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues36
DetailsBINDING: BINDING => ECO:0000305|PubMed:34996871, ECO:0000305|PubMed:35482892, ECO:0007744|PDB:7SJ7, ECO:0007744|PDB:7Z6S
ChainResidueDetails
BGLN11
NGLY144
NASN204
NASN226
DGLN11
DGLY142
DTHR143
DGLY144
DASN204
DASN226
PGLN11
BGLY142
PGLY142
PTHR143
PGLY144
PASN204
PASN226
FGLN11
FGLY142
FTHR143
FGLY144
FASN204
BTHR143
FASN226
RGLN11
RGLY142
RTHR143
RGLY144
RASN204
RASN226
BGLY144
BASN204
BASN226
NGLN11
NGLY142
NTHR143

site_idSWS_FT_FI2
Number of Residues6
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:P68363
ChainResidueDetails
BGLU69
GGLU71
GSER140
GGLY144
GTHR145
GTHR179
GASN206
GASN228
CGLN11
CGLU71
CSER140
NGLU69
CGLY144
CTHR145
CTHR179
CASN206
CASN228
IGLN11
IGLU71
ISER140
IGLY144
ITHR145
DGLU69
ITHR179
IASN206
IASN228
EGLN11
EGLU71
ESER140
EGLY144
ETHR145
ETHR179
EASN206
PGLU69
EASN228
KGLN11
KGLU71
KSER140
KGLY144
KTHR145
KTHR179
KASN206
KASN228
FGLU69
RGLU69
AASN206
AASN228
GGLN11

site_idSWS_FT_FI3
Number of Residues6
DetailsBINDING: BINDING => ECO:0000305|PubMed:34996871, ECO:0007744|PDB:7SJ7
ChainResidueDetails
BSER138
NSER138
DSER138
PSER138
FSER138
RSER138

site_idSWS_FT_FI4
Number of Residues6
DetailsMOD_RES: Phosphoserine; by CDK1 => ECO:0000269|PubMed:16371510
ChainResidueDetails
BSER172
ESER232
KSER48
KSER232
NSER172
DSER172
PSER172
FSER172
RSER172
ISER48
ISER232
ESER48

site_idSWS_FT_FI5
Number of Residues6
DetailsMOD_RES: 5-glutamyl polyglutamate => ECO:0000250|UniProtKB:Q2T9S0
ChainResidueDetails
BGLU438
NGLU438
DGLU438
PGLU438
FGLU438
RGLU438

site_idSWS_FT_FI6
Number of Residues6
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q2T9S0
ChainResidueDetails
BSER444
NSER444
DSER444
PSER444
FSER444
RSER444

site_idSWS_FT_FI7
Number of Residues6
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P68373
ChainResidueDetails
ASER439
GSER439
CSER439
ISER439
ESER439
KSER439

site_idSWS_FT_FI8
Number of Residues18
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
ChainResidueDetails
ALYS326
ILYS326
ILYS370
ELYS326
ELYS370
KLYS326
KLYS370
ALYS370
GLYS326
GLYS370
CLYS326
CLYS370

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PDB entries from 2025-06-11

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