9F30
Human carbonic anhydrase XII with 3-(Cyclooctylamino)-5-ethoxy-2,6-difluoro-4-((3-hydroxypropyl)sulfonyl)benzenesulfonamide
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS00162 |
| Number of Residues | 17 |
| Details | ALPHA_CA_1 Alpha-carbonic anhydrases signature. SEHtVsgqhFaaELHIV |
| Chain | Residue | Details |
| A | SER103-VAL119 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000250|UniProtKB:P00918 |
| Chain | Residue | Details |
| A | HIS66 | |
| B | HIS66 | |
| C | HIS66 | |
| D | HIS66 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11493685 |
| Chain | Residue | Details |
| A | HIS91 | |
| D | HIS91 | |
| D | HIS93 | |
| D | HIS117 | |
| A | HIS93 | |
| A | HIS117 | |
| B | HIS91 | |
| B | HIS93 | |
| B | HIS117 | |
| C | HIS91 | |
| C | HIS93 | |
| C | HIS117 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P00918 |
| Chain | Residue | Details |
| A | THR198 | |
| B | THR198 | |
| C | THR198 | |
| D | THR198 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN52 | |
| A | ASN134 | |
| B | ASN52 | |
| B | ASN134 | |
| C | ASN52 | |
| C | ASN134 | |
| D | ASN52 | |
| D | ASN134 |
