9EY6
Crystal structure of human tyrosinase-related protein 1 (TYRP1)
Functional Information from PROSITE/UniProt
| site_id | PS00022 |
| Number of Residues | 12 |
| Details | EGF_1 EGF-like domain signature 1. ChCngNfsGHnC |
| Chain | Residue | Details |
| A | CYS99-CYS110 |
| site_id | PS00497 |
| Number of Residues | 18 |
| Details | TYROSINASE_1 Tyrosinase CuA-binding region signature. Hegpa.FLtWHRyhLlrlE |
| Chain | Residue | Details |
| A | HIS215-GLU232 |
| site_id | PS00498 |
| Number of Residues | 12 |
| Details | TYROSINASE_2 Tyrosinase and hemocyanins CuB-binding region signature. DPiFVllHtftD |
| Chain | Residue | Details |
| A | ASP397-ASP408 |
| site_id | PS01248 |
| Number of Residues | 24 |
| Details | EGF_LAM_1 Laminin-type EGF-like (LE) domain signature. Ch.CngnfsGhnCgtCrpg.Wrgaa...........C |
| Chain | Residue | Details |
| A | CYS99-CYS122 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28661582, ECO:0007744|PDB:5M8L |
| Chain | Residue | Details |
| A | HIS192 | |
| A | HIS215 | |
| A | HIS224 | |
| A | HIS377 | |
| A | HIS381 | |
| A | HIS404 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:28661582, ECO:0007744|PDB:5M8L |
| Chain | Residue | Details |
| A | ASN96 | |
| A | ASN104 | |
| A | ASN181 | |
| A | ASN304 | |
| A | ASN350 | |
| A | ASN385 |
