9EWY

CryoEM structure of human MICAL1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003779	molecular_function	actin binding
A	0004497	molecular_function	monooxygenase activity
A	0005515	molecular_function	protein binding
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005768	cellular_component	endosome
A	0005829	cellular_component	cytosol
A	0005856	cellular_component	cytoskeleton
A	0005882	cellular_component	intermediate filament
A	0005884	cellular_component	actin filament
A	0005886	cellular_component	plasma membrane
A	0005929	cellular_component	cilium
A	0007010	biological_process	cytoskeleton organization
A	0007165	biological_process	signal transduction
A	0010008	cellular_component	endosome membrane
A	0015629	cellular_component	actin cytoskeleton
A	0016020	cellular_component	membrane
A	0016174	molecular_function	NAD(P)H oxidase H2O2-forming activity
A	0016491	molecular_function	oxidoreductase activity
A	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
A	0017124	molecular_function	SH3 domain binding
A	0019417	biological_process	sulfur oxidation
A	0019901	molecular_function	protein kinase binding
A	0030042	biological_process	actin filament depolymerization
A	0030496	cellular_component	midbody
A	0031267	molecular_function	small GTPase binding
A	0036064	cellular_component	ciliary basal body
A	0043066	biological_process	negative regulation of apoptotic process
A	0045171	cellular_component	intercellular bridge
A	0046872	molecular_function	metal ion binding
A	0051015	molecular_function	actin filament binding
A	0051017	biological_process	actin filament bundle assembly
A	0071949	molecular_function	FAD binding
A	0120025	cellular_component	plasma membrane bounded cell projection
A	0120501	molecular_function	F-actin monooxygenase activity
A	1903305	biological_process	regulation of regulated secretory pathway
A	1990026	cellular_component	hippocampal mossy fiber expansion

Functional Information from PROSITE/UniProt

site_id	PS00478
Number of Residues	35
Details	LIM_DOMAIN_1 LIM zinc-binding domain signature. CalCgehlyvlerlcvnghf.....FHrsCfrChtCeatL

Chain	Residue	Details
A	CYS697-LEU731

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	104
Details	Domain: {"description":"Calponin-homology (CH)","evidences":[{"source":"PROSITE-ProRule","id":"PRU00044","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	71
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q8VDP3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PDB","id":"2CO8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"D3ZBP4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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