9EVC

CryoEM structure of LMCA1 in E1-Ca state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005215	molecular_function	transporter activity
A	0005388	molecular_function	P-type calcium transporter activity
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0006816	biological_process	calcium ion transport
A	0015662	molecular_function	P-type ion transporter activity
A	0016020	cellular_component	membrane
A	0016887	molecular_function	ATP hydrolysis activity
A	0019829	molecular_function	ATPase-coupled monoatomic cation transmembrane transporter activity
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0046872	molecular_function	metal ion binding
A	0046873	molecular_function	metal ion transmembrane transporter activity
A	0070588	biological_process	calcium ion transmembrane transport
A	0098655	biological_process	monoatomic cation transmembrane transport
A	0098662	biological_process	inorganic cation transmembrane transport
A	0140352	biological_process	export from cell

Functional Information from PROSITE/UniProt

site_id	PS00154
Number of Residues	7
Details	ATPASE_E1_E2 E1-E2 ATPases phosphorylation site. DKTGTLT

Chain	Residue	Details
A	ASP334-THR340

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	180
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
A	LEU47-ALA67
A	LEU68-VAL88
A	LEU243-LEU263
A	MET271-PRO291
A	ILE681-LEU701
A	PHE707-LEU727
A	ALA756-MET776
A	TYR819-ALA839
A	TRP854-VAL874

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: 4-aspartylphosphate intermediate => ECO:0000250

Chain	Residue	Details
A	ASP334

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site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	VAL287
A	ALA288
A	ILE290
A	GLU292
A	ASN716
A	ASP720

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