9EP1
Structure of the Integrator arm module containing INTS10/13/14/15 subunits (state 2)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005654 | cellular_component | nucleoplasm |
| B | 0016180 | biological_process | snRNA processing |
| B | 0032039 | cellular_component | integrator complex |
| B | 0034243 | biological_process | regulation of transcription elongation by RNA polymerase II |
| B | 0034472 | biological_process | snRNA 3'-end processing |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0160232 | cellular_component | INTAC complex |
| B | 0160240 | biological_process | RNA polymerase II transcription initiation surveillance |
| D | 0005515 | molecular_function | protein binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0005654 | cellular_component | nucleoplasm |
| D | 0016180 | biological_process | snRNA processing |
| D | 0032039 | cellular_component | integrator complex |
| D | 0034243 | biological_process | regulation of transcription elongation by RNA polymerase II |
| D | 0160232 | cellular_component | INTAC complex |
| D | 0160240 | biological_process | RNA polymerase II transcription initiation surveillance |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 202 |
| Details | Domain: {"description":"VWFA"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"38823386","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38906142","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8PK5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9EOC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"38823386","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9EOC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
