9END

Crystal structure of Methanopyrus kandleri malate dehydrogenase mutant 3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004459	molecular_function	L-lactate dehydrogenase activity
A	0006089	biological_process	lactate metabolic process
A	0006090	biological_process	pyruvate metabolic process
A	0016491	molecular_function	oxidoreductase activity
B	0004459	molecular_function	L-lactate dehydrogenase activity
B	0006089	biological_process	lactate metabolic process
B	0006090	biological_process	pyruvate metabolic process
B	0016491	molecular_function	oxidoreductase activity

Functional Information from PROSITE/UniProt

site_id	PS00064
Number of Residues	7
Details	L_LDH L-lactate dehydrogenase active site. IGEHGDT

Chain	Residue	Details
A	ILE175-THR181

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:P61889

Chain	Residue	Details
A	HIS178
B	HIS178

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q60176

Chain	Residue	Details
A	GLY8
A	ASN98
A	VAL121
B	GLY8
B	ASN98
B	VAL121

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P61889

Chain	Residue	Details
A	GLN85
A	ARG91
A	ASN123
A	ARG154
B	GLN85
B	ARG91
B	ASN123
B	ARG154

---