9ELP
Cryo-EM structure of SARS-CoV-2 Omicron JN.1.11.1+S31 deletion spike protein (one RBD up state)
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host furin => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32142651, ECO:0000269|PubMed:32362314, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
| Chain | Residue | Details |
| A | ALA694 | |
| B | ALA692 | |
| C | ALA694 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host TMPRSS2 or CTSL => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
| Chain | Residue | Details |
| A | ASN824 | |
| B | ASN822 | |
| C | ASN824 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | ASN20 | |
| A | GLY1167 | |
| A | GLU1182 | |
| B | ASN20 | |
| B | GLY1165 | |
| B | GLU1180 | |
| C | ASN20 | |
| C | GLY1167 | |
| C | GLU1182 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 15 |
| Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | PHE65 | |
| B | HIS1081 | |
| C | PHE65 | |
| C | ILE128 | |
| C | ILE726 | |
| C | SER810 | |
| C | HIS1083 | |
| A | ILE128 | |
| A | ILE726 | |
| A | SER810 | |
| A | HIS1083 | |
| B | PHE65 | |
| B | ILE127 | |
| B | ILE724 | |
| B | SER808 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 9 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | ASP80 | |
| A | GLU156 | |
| A | LEU1203 | |
| B | ASP79 | |
| B | GLU155 | |
| B | LEU1201 | |
| C | ASP80 | |
| C | GLU156 | |
| C | LEU1203 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 21 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | SER172 | |
| B | HIS337 | |
| B | TYR349 | |
| B | HIS623 | |
| B | ILE664 | |
| B | ARG1105 | |
| C | SER172 | |
| C | ASP290 | |
| C | HIS339 | |
| C | TYR351 | |
| C | HIS625 | |
| A | ASP290 | |
| C | ILE666 | |
| C | ARG1107 | |
| A | HIS339 | |
| A | TYR351 | |
| A | HIS625 | |
| A | ILE666 | |
| A | ARG1107 | |
| B | SER171 | |
| B | ASP288 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) (high mannose) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | LEU242 | |
| A | PHE718 | |
| B | LEU240 | |
| B | PHE716 | |
| C | LEU242 | |
| C | PHE718 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 3 |
| Details | CARBOHYD: O-linked (GalNAc) threonine; by host => ECO:0000269|PubMed:32363391 |
| Chain | Residue | Details |
| A | ASN331 | |
| B | ASN329 | |
| C | ASN331 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 3 |
| Details | CARBOHYD: O-linked (HexNAc...) serine; by host => ECO:0000269|PubMed:32363391 |
| Chain | Residue | Details |
| A | THR333 | |
| B | THR331 | |
| C | THR333 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | TYR612 | |
| B | TYR610 | |
| C | TYR612 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 6 |
| Details | CARBOHYD: O-linked (GlcNAc...) threonine; by host GALNT1 => ECO:0000269|PubMed:34732583 |
| Chain | Residue | Details |
| A | SER685 | |
| A | VAL687 | |
| B | SER683 | |
| B | VAL685 | |
| C | SER685 | |
| C | VAL687 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | LEU1143 | |
| B | LEU1141 | |
| C | LEU1143 |
