9E2P
Complex of Human MIRO1 and TRAK1 Binding Site-2 (L570-R613)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005741 | cellular_component | mitochondrial outer membrane |
| A | 0007005 | biological_process | mitochondrion organization |
| A | 0010821 | biological_process | regulation of mitochondrion organization |
| A | 0016020 | cellular_component | membrane |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0019003 | molecular_function | GDP binding |
| A | 0019725 | biological_process | cellular homeostasis |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047497 | biological_process | mitochondrion transport along microtubule |
| A | 0097345 | biological_process | mitochondrial outer membrane permeabilization |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0003924 | molecular_function | GTPase activity |
| C | 0005509 | molecular_function | calcium ion binding |
| C | 0005515 | molecular_function | protein binding |
| C | 0005525 | molecular_function | GTP binding |
| C | 0005739 | cellular_component | mitochondrion |
| C | 0005741 | cellular_component | mitochondrial outer membrane |
| C | 0007005 | biological_process | mitochondrion organization |
| C | 0010821 | biological_process | regulation of mitochondrion organization |
| C | 0016020 | cellular_component | membrane |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016887 | molecular_function | ATP hydrolysis activity |
| C | 0019003 | molecular_function | GDP binding |
| C | 0019725 | biological_process | cellular homeostasis |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0047497 | biological_process | mitochondrion transport along microtubule |
| C | 0097345 | biological_process | mitochondrial outer membrane permeabilization |
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DQDNDGTLNdaEL |
| Chain | Residue | Details |
| A | ASP197-LEU209 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 332 |
| Details | Domain: {"description":"Miro 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00757","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 70 |
| Details | Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 70 |
| Details | Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 326 |
| Details | Domain: {"description":"Miro 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00757","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 26 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33132189","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6D71","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 30 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27605430","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KTY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27605430","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5KSO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KSP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KSY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KU1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27605430","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5KSP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KTY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27605430","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5KSO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KSY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KTY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"A1L1L6","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 8 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"27605430","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
