9E2E
The structure of the junction region of the wild-type murine native cardiac thin filament in Ca2+-free state
Functional Information from PROSITE/UniProt
| site_id | PS00326 |
| Number of Residues | 9 |
| Details | TROPOMYOSIN Tropomyosins signature. LKEAEtRAE |
| Chain | Residue | Details |
| G | LEU232-GLU240 |
| site_id | PS00406 |
| Number of Residues | 11 |
| Details | ACTINS_1 Actins signature 1. YVGDEAQs.KRG |
| Chain | Residue | Details |
| A | TYR53-GLY63 |
| site_id | PS00432 |
| Number of Residues | 9 |
| Details | ACTINS_2 Actins signature 2. WISKqEYDE |
| Chain | Residue | Details |
| A | TRP356-GLU364 |
| site_id | PS01132 |
| Number of Residues | 13 |
| Details | ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR |
| Chain | Residue | Details |
| A | LEU104-ARG116 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by CK2 => ECO:0000250|UniProtKB:P13789 |
| Chain | Residue | Details |
| K | SER2 | |
| P | SER2 | |
| I | MET1 | |
| J | MET1 | |
| L | MET1 | |
| M | MET1 | |
| N | MET1 | |
| O | MET1 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by PKC/PRKCA => ECO:0000269|PubMed:12832403 |
| Chain | Residue | Details |
| K | GLU207 | |
| E | MET47 | |
| F | MET44 | |
| F | MET47 | |
| P | GLU207 | |
| I | SER45 | |
| J | SER45 | |
| L | SER45 | |
| M | SER45 | |
| N | SER45 | |
| O | SER45 | |
| E | MET44 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by PKC/PRKCA => ECO:0000269|PubMed:12832403 |
| Chain | Residue | Details |
| K | LYS211 | |
| H | SER252 | |
| H | SER271 | |
| H | SER283 | |
| I | SER174 | |
| I | SER186 | |
| I | SER206 | |
| I | SER252 | |
| I | SER271 | |
| I | SER283 | |
| J | SER174 | |
| P | LYS211 | |
| J | SER186 | |
| J | SER206 | |
| J | SER252 | |
| J | SER271 | |
| J | SER283 | |
| L | SER174 | |
| L | SER186 | |
| L | SER206 | |
| L | SER252 | |
| L | SER271 | |
| G | SER206 | |
| L | SER283 | |
| M | SER174 | |
| M | SER186 | |
| M | SER206 | |
| M | SER252 | |
| M | SER271 | |
| M | SER283 | |
| N | SER174 | |
| N | SER186 | |
| N | SER206 | |
| G | SER252 | |
| N | SER252 | |
| N | SER271 | |
| N | SER283 | |
| O | SER174 | |
| O | SER186 | |
| O | SER206 | |
| O | SER252 | |
| O | SER271 | |
| O | SER283 | |
| G | SER271 | |
| G | SER283 | |
| H | SER174 | |
| H | SER186 | |
| H | SER206 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by PKC/PRKCA and RAF1 => ECO:0000305|PubMed:12832403 |
| Chain | Residue | Details |
| K | ALA216 | |
| P | ALA216 | |
| I | TYR261 | |
| J | TYR261 | |
| L | TYR261 | |
| M | TYR261 | |
| N | TYR261 | |
| O | TYR261 |
