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9DZM

Dimeric human OCT2 (POU2F2) POU domain bound to palindromic MORE DNA

Functional Information from GO Data
ChainGOidnamespacecontents
C0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
C0003677molecular_functionDNA binding
C0003700molecular_functionDNA-binding transcription factor activity
C0006355biological_processregulation of DNA-templated transcription
D0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
D0003677molecular_functionDNA binding
D0003700molecular_functionDNA-binding transcription factor activity
D0006355biological_processregulation of DNA-templated transcription
E0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
E0003677molecular_functionDNA binding
E0003700molecular_functionDNA-binding transcription factor activity
E0006355biological_processregulation of DNA-templated transcription
F0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
F0003677molecular_functionDNA binding
F0003700molecular_functionDNA-binding transcription factor activity
F0006355biological_processregulation of DNA-templated transcription
Functional Information from PROSITE/UniProt
site_idPS00027
Number of Residues24
DetailsHOMEOBOX_1 'Homeobox' domain signature. IAeqLhMEkeVIRVWFcNrrqkeK
ChainResidueDetails
CILE332-LYS355

site_idPS00035
Number of Residues13
DetailsPOU_1 POU-specific (POUs) domain signature 1. RRIkLGFtQgDVG
ChainResidueDetails
CARG215-GLY227

site_idPS00465
Number of Residues14
DetailsPOU_2 POU-specific (POUs) domain signature 2. SQTTISRFEaLnLS
ChainResidueDetails
CSER239-SER252

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues74
DetailsDomain: {"description":"POU-specific","evidences":[{"source":"PROSITE-ProRule","id":"PRU00530","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

249524

PDB entries from 2026-02-18

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