9DZF
Human GC-A bound to ANP and XX16
Functional Information from PROSITE/UniProt
| site_id | PS00263 |
| Number of Residues | 17 |
| Details | NATRIURETIC_PEPTIDE Natriuretic peptides signature. CFGgrmDRIgaqSglGC |
| Chain | Residue | Details |
| C | CYS7-CYS23 |
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
| Chain | Residue | Details |
| L | TYR192-HIS198 | |
| H | TYR206-HIS212 |
| site_id | PS00452 |
| Number of Residues | 24 |
| Details | GUANYLATE_CYCLASE_1 Guanylate cyclase signature. GVV.GlkmprYcLFGDTVNtasrmE |
| Chain | Residue | Details |
| A | GLY951-GLU974 |
| site_id | PS00458 |
| Number of Residues | 18 |
| Details | ANF_RECEPTORS Natriuretic peptides receptors signature. GPgCvYaAApVgRftaHW |
| Chain | Residue | Details |
| A | GLY83-TRP100 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 22 |
| Details | Peptide: {"description":"Atriopeptin-2","featureId":"PRO_0000449733","evidences":[{"source":"UniProtKB","id":"P01161","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 20 |
| Details | Peptide: {"description":"Atriopeptin-1","featureId":"PRO_0000449734","evidences":[{"source":"UniProtKB","id":"P01161","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by MME","evidences":[{"source":"PubMed","id":"2972276","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"2528951","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
