Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9DZ8

Catalytic domain of Dihydrolipoamide Succinytransferase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
A	0006099	biological_process	tricarboxylic acid cycle
A	0016746	molecular_function	acyltransferase activity
A	0045252	cellular_component	oxoglutarate dehydrogenase complex
B	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
B	0006099	biological_process	tricarboxylic acid cycle
B	0016746	molecular_function	acyltransferase activity
B	0045252	cellular_component	oxoglutarate dehydrogenase complex
C	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
C	0006099	biological_process	tricarboxylic acid cycle
C	0016746	molecular_function	acyltransferase activity
C	0045252	cellular_component	oxoglutarate dehydrogenase complex
D	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
D	0006099	biological_process	tricarboxylic acid cycle
D	0016746	molecular_function	acyltransferase activity
D	0045252	cellular_component	oxoglutarate dehydrogenase complex
E	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
E	0006099	biological_process	tricarboxylic acid cycle
E	0016746	molecular_function	acyltransferase activity
E	0045252	cellular_component	oxoglutarate dehydrogenase complex
F	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
F	0006099	biological_process	tricarboxylic acid cycle
F	0016746	molecular_function	acyltransferase activity
F	0045252	cellular_component	oxoglutarate dehydrogenase complex
G	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
G	0006099	biological_process	tricarboxylic acid cycle
G	0016746	molecular_function	acyltransferase activity
G	0045252	cellular_component	oxoglutarate dehydrogenase complex
H	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
H	0006099	biological_process	tricarboxylic acid cycle
H	0016746	molecular_function	acyltransferase activity
H	0045252	cellular_component	oxoglutarate dehydrogenase complex
I	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
I	0006099	biological_process	tricarboxylic acid cycle
I	0016746	molecular_function	acyltransferase activity
I	0045252	cellular_component	oxoglutarate dehydrogenase complex
J	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
J	0006099	biological_process	tricarboxylic acid cycle
J	0016746	molecular_function	acyltransferase activity
J	0045252	cellular_component	oxoglutarate dehydrogenase complex
K	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
K	0006099	biological_process	tricarboxylic acid cycle
K	0016746	molecular_function	acyltransferase activity
K	0045252	cellular_component	oxoglutarate dehydrogenase complex
L	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
L	0006099	biological_process	tricarboxylic acid cycle
L	0016746	molecular_function	acyltransferase activity
L	0045252	cellular_component	oxoglutarate dehydrogenase complex
M	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
M	0006099	biological_process	tricarboxylic acid cycle
M	0016746	molecular_function	acyltransferase activity
M	0045252	cellular_component	oxoglutarate dehydrogenase complex
N	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
N	0006099	biological_process	tricarboxylic acid cycle
N	0016746	molecular_function	acyltransferase activity
N	0045252	cellular_component	oxoglutarate dehydrogenase complex
O	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
O	0006099	biological_process	tricarboxylic acid cycle
O	0016746	molecular_function	acyltransferase activity
O	0045252	cellular_component	oxoglutarate dehydrogenase complex
P	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
P	0006099	biological_process	tricarboxylic acid cycle
P	0016746	molecular_function	acyltransferase activity
P	0045252	cellular_component	oxoglutarate dehydrogenase complex
Q	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
Q	0006099	biological_process	tricarboxylic acid cycle
Q	0016746	molecular_function	acyltransferase activity
Q	0045252	cellular_component	oxoglutarate dehydrogenase complex
R	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
R	0006099	biological_process	tricarboxylic acid cycle
R	0016746	molecular_function	acyltransferase activity
R	0045252	cellular_component	oxoglutarate dehydrogenase complex
S	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
S	0006099	biological_process	tricarboxylic acid cycle
S	0016746	molecular_function	acyltransferase activity
S	0045252	cellular_component	oxoglutarate dehydrogenase complex
T	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
T	0006099	biological_process	tricarboxylic acid cycle
T	0016746	molecular_function	acyltransferase activity
T	0045252	cellular_component	oxoglutarate dehydrogenase complex
U	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
U	0006099	biological_process	tricarboxylic acid cycle
U	0016746	molecular_function	acyltransferase activity
U	0045252	cellular_component	oxoglutarate dehydrogenase complex
V	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
V	0006099	biological_process	tricarboxylic acid cycle
V	0016746	molecular_function	acyltransferase activity
V	0045252	cellular_component	oxoglutarate dehydrogenase complex
W	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
W	0006099	biological_process	tricarboxylic acid cycle
W	0016746	molecular_function	acyltransferase activity
W	0045252	cellular_component	oxoglutarate dehydrogenase complex
X	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
X	0006099	biological_process	tricarboxylic acid cycle
X	0016746	molecular_function	acyltransferase activity
X	0045252	cellular_component	oxoglutarate dehydrogenase complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	48
Details	Active site: {"evidences":[{"source":"PubMed","id":"10739245","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9677295","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
A	THR323	electrostatic stabiliser, polar interaction
A	HIS375	activator, proton acceptor, proton donor

site_id	MCSA10
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
J	THR323	electrostatic stabiliser, polar interaction
J	HIS375	activator, proton acceptor, proton donor

site_id	MCSA11
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
K	THR323	electrostatic stabiliser, polar interaction
K	HIS375	activator, proton acceptor, proton donor

site_id	MCSA12
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
L	THR323	electrostatic stabiliser, polar interaction
L	HIS375	activator, proton acceptor, proton donor

site_id	MCSA13
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
M	THR323	electrostatic stabiliser, polar interaction
M	HIS375	activator, proton acceptor, proton donor

site_id	MCSA14
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
N	THR323	electrostatic stabiliser, polar interaction
N	HIS375	activator, proton acceptor, proton donor

site_id	MCSA15
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
O	THR323	electrostatic stabiliser, polar interaction
O	HIS375	activator, proton acceptor, proton donor

site_id	MCSA16
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
P	THR323	electrostatic stabiliser, polar interaction
P	HIS375	activator, proton acceptor, proton donor

site_id	MCSA17
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
Q	THR323	electrostatic stabiliser, polar interaction
Q	HIS375	activator, proton acceptor, proton donor

site_id	MCSA18
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
R	THR323	electrostatic stabiliser, polar interaction
R	HIS375	activator, proton acceptor, proton donor

site_id	MCSA19
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
S	THR323	electrostatic stabiliser, polar interaction
S	HIS375	activator, proton acceptor, proton donor

site_id	MCSA2
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
B	THR323	electrostatic stabiliser, polar interaction
B	HIS375	activator, proton acceptor, proton donor

site_id	MCSA20
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
T	THR323	electrostatic stabiliser, polar interaction
T	HIS375	activator, proton acceptor, proton donor

site_id	MCSA21
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
U	THR323	electrostatic stabiliser, polar interaction
U	HIS375	activator, proton acceptor, proton donor

site_id	MCSA22
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
V	THR323	electrostatic stabiliser, polar interaction
V	HIS375	activator, proton acceptor, proton donor

site_id	MCSA23
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
W	THR323	electrostatic stabiliser, polar interaction
W	HIS375	activator, proton acceptor, proton donor

site_id	MCSA24
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
X	THR323	electrostatic stabiliser, polar interaction
X	HIS375	activator, proton acceptor, proton donor

site_id	MCSA3
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
C	THR323	electrostatic stabiliser, polar interaction
C	HIS375	activator, proton acceptor, proton donor

site_id	MCSA4
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
D	THR323	electrostatic stabiliser, polar interaction
D	HIS375	activator, proton acceptor, proton donor

site_id	MCSA5
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
E	THR323	electrostatic stabiliser, polar interaction
E	HIS375	activator, proton acceptor, proton donor

site_id	MCSA6
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
F	THR323	electrostatic stabiliser, polar interaction
F	HIS375	activator, proton acceptor, proton donor

site_id	MCSA7
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
G	THR323	electrostatic stabiliser, polar interaction
G	HIS375	activator, proton acceptor, proton donor

site_id	MCSA8
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
H	THR323	electrostatic stabiliser, polar interaction
H	HIS375	activator, proton acceptor, proton donor

site_id	MCSA9
Number of Residues	2
Details	M-CSA 704

Chain	Residue	Details
I	THR323	electrostatic stabiliser, polar interaction
I	HIS375	activator, proton acceptor, proton donor

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)