Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9DYH

BEST2 + glutamate open state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005217	molecular_function	intracellularly ligand-gated monoatomic ion channel activity
A	0005254	molecular_function	chloride channel activity
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0005929	cellular_component	cilium
A	0006811	biological_process	monoatomic ion transport
A	0006821	biological_process	chloride transport
A	0007608	biological_process	sensory perception of smell
A	0015267	molecular_function	channel activity
A	0015701	biological_process	bicarbonate transport
A	0016323	cellular_component	basolateral plasma membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0034707	cellular_component	chloride channel complex
A	0046872	molecular_function	metal ion binding
A	0051899	biological_process	membrane depolarization
A	0098655	biological_process	monoatomic cation transmembrane transport
A	0099094	molecular_function	ligand-gated monoatomic cation channel activity
A	0099095	molecular_function	ligand-gated monoatomic anion channel activity
A	0160133	molecular_function	bicarbonate channel activity
A	1902476	biological_process	chloride transmembrane transport
B	0005217	molecular_function	intracellularly ligand-gated monoatomic ion channel activity
B	0005254	molecular_function	chloride channel activity
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0005929	cellular_component	cilium
B	0006811	biological_process	monoatomic ion transport
B	0006821	biological_process	chloride transport
B	0007608	biological_process	sensory perception of smell
B	0015267	molecular_function	channel activity
B	0015701	biological_process	bicarbonate transport
B	0016323	cellular_component	basolateral plasma membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0034707	cellular_component	chloride channel complex
B	0046872	molecular_function	metal ion binding
B	0051899	biological_process	membrane depolarization
B	0098655	biological_process	monoatomic cation transmembrane transport
B	0099094	molecular_function	ligand-gated monoatomic cation channel activity
B	0099095	molecular_function	ligand-gated monoatomic anion channel activity
B	0160133	molecular_function	bicarbonate channel activity
B	1902476	biological_process	chloride transmembrane transport
C	0005217	molecular_function	intracellularly ligand-gated monoatomic ion channel activity
C	0005254	molecular_function	chloride channel activity
C	0005515	molecular_function	protein binding
C	0005886	cellular_component	plasma membrane
C	0005929	cellular_component	cilium
C	0006811	biological_process	monoatomic ion transport
C	0006821	biological_process	chloride transport
C	0007608	biological_process	sensory perception of smell
C	0015267	molecular_function	channel activity
C	0015701	biological_process	bicarbonate transport
C	0016323	cellular_component	basolateral plasma membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0034707	cellular_component	chloride channel complex
C	0046872	molecular_function	metal ion binding
C	0051899	biological_process	membrane depolarization
C	0098655	biological_process	monoatomic cation transmembrane transport
C	0099094	molecular_function	ligand-gated monoatomic cation channel activity
C	0099095	molecular_function	ligand-gated monoatomic anion channel activity
C	0160133	molecular_function	bicarbonate channel activity
C	1902476	biological_process	chloride transmembrane transport
D	0005217	molecular_function	intracellularly ligand-gated monoatomic ion channel activity
D	0005254	molecular_function	chloride channel activity
D	0005515	molecular_function	protein binding
D	0005886	cellular_component	plasma membrane
D	0005929	cellular_component	cilium
D	0006811	biological_process	monoatomic ion transport
D	0006821	biological_process	chloride transport
D	0007608	biological_process	sensory perception of smell
D	0015267	molecular_function	channel activity
D	0015701	biological_process	bicarbonate transport
D	0016323	cellular_component	basolateral plasma membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0034707	cellular_component	chloride channel complex
D	0046872	molecular_function	metal ion binding
D	0051899	biological_process	membrane depolarization
D	0098655	biological_process	monoatomic cation transmembrane transport
D	0099094	molecular_function	ligand-gated monoatomic cation channel activity
D	0099095	molecular_function	ligand-gated monoatomic anion channel activity
D	0160133	molecular_function	bicarbonate channel activity
D	1902476	biological_process	chloride transmembrane transport
E	0005217	molecular_function	intracellularly ligand-gated monoatomic ion channel activity
E	0005254	molecular_function	chloride channel activity
E	0005515	molecular_function	protein binding
E	0005886	cellular_component	plasma membrane
E	0005929	cellular_component	cilium
E	0006811	biological_process	monoatomic ion transport
E	0006821	biological_process	chloride transport
E	0007608	biological_process	sensory perception of smell
E	0015267	molecular_function	channel activity
E	0015701	biological_process	bicarbonate transport
E	0016323	cellular_component	basolateral plasma membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0034707	cellular_component	chloride channel complex
E	0046872	molecular_function	metal ion binding
E	0051899	biological_process	membrane depolarization
E	0098655	biological_process	monoatomic cation transmembrane transport
E	0099094	molecular_function	ligand-gated monoatomic cation channel activity
E	0099095	molecular_function	ligand-gated monoatomic anion channel activity
E	0160133	molecular_function	bicarbonate channel activity
E	1902476	biological_process	chloride transmembrane transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	345
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"35789156","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8D1E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8D1F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8D1G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8D1H","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	130
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	775
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	5
Details	Binding site: {"description":"in other chain","evidences":[{"source":"PubMed","id":"35789156","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8D1E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8D1F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8D1G","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35789156","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8D1E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8D1F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8D1G","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)