9DY7

Proteus vulgaris tryptophan indole-lyase complexed with L-ethionine and Na+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006569	biological_process	L-tryptophan catabolic process
A	0009034	molecular_function	tryptophanase activity
A	0016829	molecular_function	lyase activity
B	0006569	biological_process	L-tryptophan catabolic process
B	0009034	molecular_function	tryptophanase activity
B	0016829	molecular_function	lyase activity
C	0006569	biological_process	L-tryptophan catabolic process
C	0009034	molecular_function	tryptophanase activity
C	0016829	molecular_function	lyase activity
D	0006569	biological_process	L-tryptophan catabolic process
D	0009034	molecular_function	tryptophanase activity
D	0016829	molecular_function	lyase activity

Functional Information from PROSITE/UniProt

site_id	PS00853
Number of Residues	19
Details	BETA_ELIM_LYASE Beta-eliminating lyases pyridoxal-phosphate attachment site. YaDaltMSAKKDpLLnIGG

Chain	Residue	Details
A	TYR256-GLY274
B	TYR256-GLY274

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Modified residue: {"description":"N6-(pyridoxal phosphate)lysine"}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	7
Details	M-CSA 410

Chain	Residue	Details
B	TYR72	proton shuttle (general acid/base)
B	PHE132	steric role
B	ASP133	electrostatic stabiliser, proton shuttle (general acid/base)
B	ASP223	electrostatic stabiliser
B	ALA225	steric role
B	LYS266	covalent catalysis, proton shuttle (general acid/base)
B	HIS458	activator, electrostatic stabiliser

---

site_id	MCSA2
Number of Residues	7
Details	M-CSA 410

Chain	Residue	Details
D	TYR72	proton shuttle (general acid/base)
D	PHE132	steric role
D	ASP133	electrostatic stabiliser, proton shuttle (general acid/base)
D	ASP223	electrostatic stabiliser
D	ALA225	steric role
D	LYS266	covalent catalysis, proton shuttle (general acid/base)
D	HIS458	activator, electrostatic stabiliser

---