9DXV

Crystal structure of cobalt-incorporated human 2-aminoethanethiol (aka cysteamine) dioxygenase (ADO) variant C18S/C239S in complex with CP6-L8K-Ser

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0005515	molecular_function	protein binding
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0016491	molecular_function	oxidoreductase activity
A	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
A	0046872	molecular_function	metal ion binding
A	0047800	molecular_function	cysteamine dioxygenase activity
A	0051213	molecular_function	dioxygenase activity
A	0071456	biological_process	cellular response to hypoxia

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"34508780","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7REI","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Cross-link: {"description":"3'-(S-cysteinyl)-tyrosine (Cys-Tyr)","evidences":[{"source":"PubMed","id":"29752763","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---