9DX2

Human GATOR2 complex - CASTOR1 bound state

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0005515	molecular_function	protein binding
E	0005829	cellular_component	cytosol
E	0034198	biological_process	cellular response to amino acid starvation
E	0034618	molecular_function	arginine binding
E	0042802	molecular_function	identical protein binding
E	0061700	cellular_component	GATOR2 complex
E	0140299	molecular_function	molecular sensor activity
E	0140311	molecular_function	protein sequestering activity
E	1903577	biological_process	cellular response to L-arginine
E	1904262	biological_process	negative regulation of TORC1 signaling
E	1904263	biological_process	positive regulation of TORC1 signaling
F	0005515	molecular_function	protein binding
F	0005829	cellular_component	cytosol
F	0034198	biological_process	cellular response to amino acid starvation
F	0034618	molecular_function	arginine binding
F	0042802	molecular_function	identical protein binding
F	0061700	cellular_component	GATOR2 complex
F	0140299	molecular_function	molecular sensor activity
F	0140311	molecular_function	protein sequestering activity
F	1903577	biological_process	cellular response to L-arginine
F	1904262	biological_process	negative regulation of TORC1 signaling
F	1904263	biological_process	positive regulation of TORC1 signaling
G	0005515	molecular_function	protein binding
G	0005829	cellular_component	cytosol
G	0034198	biological_process	cellular response to amino acid starvation
G	0034618	molecular_function	arginine binding
G	0042802	molecular_function	identical protein binding
G	0061700	cellular_component	GATOR2 complex
G	0140299	molecular_function	molecular sensor activity
G	0140311	molecular_function	protein sequestering activity
G	1903577	biological_process	cellular response to L-arginine
G	1904262	biological_process	negative regulation of TORC1 signaling
G	1904263	biological_process	positive regulation of TORC1 signaling

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	132
Details	Domain: {"description":"ACT 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	183
Details	Domain: {"description":"ACT 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	21
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27487210","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5I2C","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Modified residue: {"description":"Phosphoserine; by PKB/AKT1","evidences":[{"source":"PubMed","id":"33594058","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---