9DUI
Re-refined of Crystal structure of dopa decarboxylase in complex with the inhibitor carbidopa (1JS3) with ketoenamine form of carbidopa
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004058 | molecular_function | aromatic-L-amino-acid decarboxylase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006584 | biological_process | catecholamine metabolic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0036467 | molecular_function | 5-hydroxy-L-tryptophan decarboxylase activity |
| A | 0036468 | molecular_function | L-dopa decarboxylase activity |
| A | 0042416 | biological_process | dopamine biosynthetic process |
| A | 0042423 | biological_process | catecholamine biosynthetic process |
| A | 0042427 | biological_process | serotonin biosynthetic process |
| B | 0004058 | molecular_function | aromatic-L-amino-acid decarboxylase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006584 | biological_process | catecholamine metabolic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0036467 | molecular_function | 5-hydroxy-L-tryptophan decarboxylase activity |
| B | 0036468 | molecular_function | L-dopa decarboxylase activity |
| B | 0042416 | biological_process | dopamine biosynthetic process |
| B | 0042423 | biological_process | catecholamine biosynthetic process |
| B | 0042427 | biological_process | serotonin biosynthetic process |
Functional Information from PROSITE/UniProt
| site_id | PS00392 |
| Number of Residues | 22 |
| Details | DDC_GAD_HDC_YDC DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. SFnFnphKWLlVnFDCsaMWvK |
| Chain | Residue | Details |
| A | SER296-LYS317 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 114 |
| Details | Repeat: {"description":"1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 120 |
| Details | Repeat: {"description":"2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 240 |
| Details | Region: {"description":"2 X approximate tandem repeats"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11685243","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1JS3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P20711","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"1935935","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"PubMed","id":"11685243","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
