9DO4

Structure of T4 RNA Ligase 1 bound to ATP and Mg

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0003972	molecular_function	RNA ligase (ATP) activity
B	0005524	molecular_function	ATP binding
B	0016874	molecular_function	ligase activity
B	0042245	biological_process	RNA repair
B	0046872	molecular_function	metal ion binding
B	0098004	biological_process	virus tail fiber assembly

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: N6-AMP-lysine intermediate => ECO:0000255|HAMAP-Rule:MF_04149, ECO:0000269|PubMed:3882425

Chain	Residue	Details
B	LYS99

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_04149, ECO:0000269|PubMed:28223499

Chain	Residue	Details
B	TYR37
B	ARG54
B	LYS75
B	GLU159
B	LYS240
B	LYS242

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_04149, ECO:0000269|PubMed:16263720, ECO:0000269|PubMed:28223499

Chain	Residue	Details
B	ASP272

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site_id	SWS_FT_FI4
Number of Residues	2
Details	SITE: Essential for RNA ligase activity => ECO:0000255|HAMAP-Rule:MF_04149, ECO:0000269|PubMed:17068206

Chain	Residue	Details
B	GLU159
B	TYR246

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