9DNS
Cryo-EM structure of Tom1-UBE2D2-ubiquitin complex
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | SITE: Interacts with activating enzyme |
| Chain | Residue | Details |
| U | ARG54 | |
| U | ARG72 | |
| V | ARG54 | |
| V | ARG72 | |
| W | ARG54 | |
| W | ARG72 | |
| X | ARG54 | |
| X | ARG72 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Essential for function |
| Chain | Residue | Details |
| U | HIS68 | |
| V | HIS68 | |
| W | HIS68 | |
| X | HIS68 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine; by PINK1 => ECO:0000269|PubMed:24660806, ECO:0000269|PubMed:24751536, ECO:0000269|PubMed:24784582, ECO:0000269|PubMed:25527291 |
| Chain | Residue | Details |
| U | SER65 | |
| V | SER65 | |
| W | SER65 | |
| X | SER65 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: (Microbial infection) ADP-ribosylthreonine => ECO:0000269|PubMed:32330457 |
| Chain | Residue | Details |
| U | THR66 | |
| V | THR66 | |
| W | THR66 | |
| X | THR66 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | MOD_RES: ADP-ribosylglycine => ECO:0000269|PubMed:28525742 |
| Chain | Residue | Details |
| U | GLY76 | |
| V | GLY76 | |
| W | GLY76 | |
| X | GLY76 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603 |
| Chain | Residue | Details |
| U | LYS6 | |
| V | LYS6 | |
| W | LYS6 | |
| X | LYS6 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 8 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins) |
| Chain | Residue | Details |
| U | GLY76 | |
| V | GLY76 | |
| W | GLY76 | |
| X | GLY76 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 8 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:16543144 |
| Chain | Residue | Details |
| U | LYS11 | |
| U | LYS48 | |
| V | LYS11 | |
| V | LYS48 | |
| W | LYS11 | |
| W | LYS48 | |
| X | LYS11 | |
| X | LYS48 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:15466860 |
| Chain | Residue | Details |
| U | LYS27 | |
| V | LYS27 | |
| W | LYS27 | |
| X | LYS27 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:25752573, ECO:0000269|PubMed:25752577, ECO:0000269|PubMed:34239127 |
| Chain | Residue | Details |
| U | LYS29 | |
| V | LYS29 | |
| W | LYS29 | |
| X | LYS29 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25752577 |
| Chain | Residue | Details |
| U | LYS33 | |
| V | LYS33 | |
| W | LYS33 | |
| X | LYS33 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:18719106 |
| Chain | Residue | Details |
| U | LYS63 | |
| V | LYS63 | |
| W | LYS63 | |
| X | LYS63 |
