9D5G
Crystal structure of the ILK/alpha-parvin core complex bound to 4-methyl erlotinib
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| AAAA | 0004672 | molecular_function | protein kinase activity |
| AAAA | 0005524 | molecular_function | ATP binding |
| AAAA | 0006468 | biological_process | protein phosphorylation |
| BBBB | 0003779 | molecular_function | actin binding |
| BBBB | 0007155 | biological_process | cell adhesion |
| BBBB | 0030036 | biological_process | actin cytoskeleton organization |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 253 |
| Details | Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Motif: {"description":"Nuclear localization signal","evidences":[{"source":"PubMed","id":"17420447","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20005845","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21524996","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3KMW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3REP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21524996","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3REP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20005845","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3KMW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by PAK1","evidences":[{"source":"PubMed","id":"17420447","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"O55222","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 107 |
| Details | Domain: {"description":"Calponin-homology (CH) 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00044","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
