Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGQGASGTVYtAmdvatgqe..........VAIK |
| Chain | Residue | Details |
| A | ILE276-LYS299 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000269|PubMed:22153498 |
| Chain | Residue | Details |
| A | ASN389 | |
| B | ASN389 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22153498 |
| Chain | Residue | Details |
| A | ILE276 | |
| A | LYS299 | |
| A | GLU345 | |
| B | ILE276 | |
| B | LYS299 | |
| B | GLU345 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by JAK2 => ECO:0000269|PubMed:17726028, ECO:0000269|PubMed:17989089 |
| Chain | Residue | Details |
| A | TYR285 | |
| B | TYR285 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by autocatalysis, BRSK2 and PDPK1 => ECO:0000269|PubMed:10551809, ECO:0000269|PubMed:10995762, ECO:0000269|PubMed:22153498, ECO:0000269|PubMed:22669945 |
| Chain | Residue | Details |
| A | GLU423 | |
| B | GLU423 |
