9D3Y
Crystal structure of the catalytic region of human MASP-2 with specific inhibitor Compound S2
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScrGDSGGALV |
| Chain | Residue | Details |
| A | ASP627-VAL638 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS483 | |
| A | ASP532 | |
| A | SER633 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by autolysis => ECO:0000269|PubMed:16040602 |
| Chain | Residue | Details |
| A | ARG444 |
