9D20

Crystal structure of DLK1 in complex with ACVR2B

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
A	0005524	molecular_function	ATP binding
A	0007178	biological_process	cell surface receptor protein serine/threonine kinase signaling pathway
A	0016020	cellular_component	membrane
B	0005509	molecular_function	calcium ion binding
D	0005509	molecular_function	calcium ion binding
E	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
E	0005524	molecular_function	ATP binding
E	0007178	biological_process	cell surface receptor protein serine/threonine kinase signaling pathway
E	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00010
Number of Residues	12
Details	ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CtDiggdFrCrC

Chain	Residue	Details
D	CYS185-CYS196

---

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. ClCkpEftGLtC

Chain	Residue	Details
D	CYS233-CYS244

---

site_id	PS01186
Number of Residues	12
Details	EGF_2 EGF-like domain signature 2. CrCpaGFidkt....C

Chain	Residue	Details
D	CYS194-CYS205

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"22718755","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	74
Details	Domain: {"description":"EGF-like 6","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; atypical; partial","evidences":[{"source":"PubMed","id":"7925474","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Glycosylation: {"description":"O-linked (GalNAc...) serine","evidences":[{"source":"PubMed","id":"7925474","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Glycosylation: {"description":"O-linked (GalNAc...) threonine; partial","evidences":[{"source":"PubMed","id":"7925474","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Glycosylation: {"description":"O-linked (GalNAc...) serine; partial","evidences":[{"source":"PubMed","id":"7925474","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---