9CZ2

Cryo-EM structure of a nautilus-like HflK/C assembly in complex with FtsH AAA protease

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004176	molecular_function	ATP-dependent peptidase activity
A	0004222	molecular_function	metalloendopeptidase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
A	0008270	molecular_function	zinc ion binding
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0030163	biological_process	protein catabolic process
A	0046872	molecular_function	metal ion binding
A	0098796	cellular_component	membrane protein complex
B	0000166	molecular_function	nucleotide binding
B	0004176	molecular_function	ATP-dependent peptidase activity
B	0004222	molecular_function	metalloendopeptidase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0006508	biological_process	proteolysis
B	0008233	molecular_function	peptidase activity
B	0008237	molecular_function	metallopeptidase activity
B	0008270	molecular_function	zinc ion binding
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0030163	biological_process	protein catabolic process
B	0046872	molecular_function	metal ion binding
B	0098796	cellular_component	membrane protein complex
C	0000166	molecular_function	nucleotide binding
C	0004176	molecular_function	ATP-dependent peptidase activity
C	0004222	molecular_function	metalloendopeptidase activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005886	cellular_component	plasma membrane
C	0006508	biological_process	proteolysis
C	0008233	molecular_function	peptidase activity
C	0008237	molecular_function	metallopeptidase activity
C	0008270	molecular_function	zinc ion binding
C	0016020	cellular_component	membrane
C	0016787	molecular_function	hydrolase activity
C	0016887	molecular_function	ATP hydrolysis activity
C	0030163	biological_process	protein catabolic process
C	0046872	molecular_function	metal ion binding
C	0098796	cellular_component	membrane protein complex
D	0000166	molecular_function	nucleotide binding
D	0004176	molecular_function	ATP-dependent peptidase activity
D	0004222	molecular_function	metalloendopeptidase activity
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005886	cellular_component	plasma membrane
D	0006508	biological_process	proteolysis
D	0008233	molecular_function	peptidase activity
D	0008237	molecular_function	metallopeptidase activity
D	0008270	molecular_function	zinc ion binding
D	0016020	cellular_component	membrane
D	0016787	molecular_function	hydrolase activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0030163	biological_process	protein catabolic process
D	0046872	molecular_function	metal ion binding
D	0098796	cellular_component	membrane protein complex
E	0000166	molecular_function	nucleotide binding
E	0004176	molecular_function	ATP-dependent peptidase activity
E	0004222	molecular_function	metalloendopeptidase activity
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005886	cellular_component	plasma membrane
E	0006508	biological_process	proteolysis
E	0008233	molecular_function	peptidase activity
E	0008237	molecular_function	metallopeptidase activity
E	0008270	molecular_function	zinc ion binding
E	0016020	cellular_component	membrane
E	0016787	molecular_function	hydrolase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0030163	biological_process	protein catabolic process
E	0046872	molecular_function	metal ion binding
E	0098796	cellular_component	membrane protein complex
F	0000166	molecular_function	nucleotide binding
F	0004176	molecular_function	ATP-dependent peptidase activity
F	0004222	molecular_function	metalloendopeptidase activity
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005886	cellular_component	plasma membrane
F	0006508	biological_process	proteolysis
F	0008233	molecular_function	peptidase activity
F	0008237	molecular_function	metallopeptidase activity
F	0008270	molecular_function	zinc ion binding
F	0016020	cellular_component	membrane
F	0016787	molecular_function	hydrolase activity
F	0016887	molecular_function	ATP hydrolysis activity
F	0030163	biological_process	protein catabolic process
F	0046872	molecular_function	metal ion binding
F	0098796	cellular_component	membrane protein complex
G	0000166	molecular_function	nucleotide binding
G	0004176	molecular_function	ATP-dependent peptidase activity
G	0004222	molecular_function	metalloendopeptidase activity
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005886	cellular_component	plasma membrane
G	0006508	biological_process	proteolysis
G	0008233	molecular_function	peptidase activity
G	0008237	molecular_function	metallopeptidase activity
G	0008270	molecular_function	zinc ion binding
G	0016020	cellular_component	membrane
G	0016787	molecular_function	hydrolase activity
G	0016887	molecular_function	ATP hydrolysis activity
G	0030163	biological_process	protein catabolic process
G	0046872	molecular_function	metal ion binding
G	0098796	cellular_component	membrane protein complex
H	0000166	molecular_function	nucleotide binding
H	0004176	molecular_function	ATP-dependent peptidase activity
H	0004222	molecular_function	metalloendopeptidase activity
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005886	cellular_component	plasma membrane
H	0006508	biological_process	proteolysis
H	0008233	molecular_function	peptidase activity
H	0008237	molecular_function	metallopeptidase activity
H	0008270	molecular_function	zinc ion binding
H	0016020	cellular_component	membrane
H	0016787	molecular_function	hydrolase activity
H	0016887	molecular_function	ATP hydrolysis activity
H	0030163	biological_process	protein catabolic process
H	0046872	molecular_function	metal ion binding
H	0098796	cellular_component	membrane protein complex
I	0000166	molecular_function	nucleotide binding
I	0004176	molecular_function	ATP-dependent peptidase activity
I	0004222	molecular_function	metalloendopeptidase activity
I	0005515	molecular_function	protein binding
I	0005524	molecular_function	ATP binding
I	0005886	cellular_component	plasma membrane
I	0006508	biological_process	proteolysis
I	0008233	molecular_function	peptidase activity
I	0008237	molecular_function	metallopeptidase activity
I	0008270	molecular_function	zinc ion binding
I	0016020	cellular_component	membrane
I	0016787	molecular_function	hydrolase activity
I	0016887	molecular_function	ATP hydrolysis activity
I	0030163	biological_process	protein catabolic process
I	0046872	molecular_function	metal ion binding
I	0098796	cellular_component	membrane protein complex
J	0000166	molecular_function	nucleotide binding
J	0004176	molecular_function	ATP-dependent peptidase activity
J	0004222	molecular_function	metalloendopeptidase activity
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005886	cellular_component	plasma membrane
J	0006508	biological_process	proteolysis
J	0008233	molecular_function	peptidase activity
J	0008237	molecular_function	metallopeptidase activity
J	0008270	molecular_function	zinc ion binding
J	0016020	cellular_component	membrane
J	0016787	molecular_function	hydrolase activity
J	0016887	molecular_function	ATP hydrolysis activity
J	0030163	biological_process	protein catabolic process
J	0046872	molecular_function	metal ion binding
J	0098796	cellular_component	membrane protein complex
K	0000166	molecular_function	nucleotide binding
K	0004176	molecular_function	ATP-dependent peptidase activity
K	0004222	molecular_function	metalloendopeptidase activity
K	0005515	molecular_function	protein binding
K	0005524	molecular_function	ATP binding
K	0005886	cellular_component	plasma membrane
K	0006508	biological_process	proteolysis
K	0008233	molecular_function	peptidase activity
K	0008237	molecular_function	metallopeptidase activity
K	0008270	molecular_function	zinc ion binding
K	0016020	cellular_component	membrane
K	0016787	molecular_function	hydrolase activity
K	0016887	molecular_function	ATP hydrolysis activity
K	0030163	biological_process	protein catabolic process
K	0046872	molecular_function	metal ion binding
K	0098796	cellular_component	membrane protein complex
L	0000166	molecular_function	nucleotide binding
L	0004176	molecular_function	ATP-dependent peptidase activity
L	0004222	molecular_function	metalloendopeptidase activity
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0005886	cellular_component	plasma membrane
L	0006508	biological_process	proteolysis
L	0008233	molecular_function	peptidase activity
L	0008237	molecular_function	metallopeptidase activity
L	0008270	molecular_function	zinc ion binding
L	0016020	cellular_component	membrane
L	0016787	molecular_function	hydrolase activity
L	0016887	molecular_function	ATP hydrolysis activity
L	0030163	biological_process	protein catabolic process
L	0046872	molecular_function	metal ion binding
L	0098796	cellular_component	membrane protein complex
XA	0005515	molecular_function	protein binding
XA	0005829	cellular_component	cytosol
XA	0005886	cellular_component	plasma membrane
XA	0009408	biological_process	response to heat
XA	0016020	cellular_component	membrane
XA	0098796	cellular_component	membrane protein complex
XB	0005515	molecular_function	protein binding
XB	0005886	cellular_component	plasma membrane
XB	0009408	biological_process	response to heat
XB	0016020	cellular_component	membrane
XB	0052547	biological_process	regulation of peptidase activity
XB	0098796	cellular_component	membrane protein complex
XB	0098797	cellular_component	plasma membrane protein complex
XC	0005515	molecular_function	protein binding
XC	0005829	cellular_component	cytosol
XC	0005886	cellular_component	plasma membrane
XC	0009408	biological_process	response to heat
XC	0016020	cellular_component	membrane
XC	0098796	cellular_component	membrane protein complex
XD	0005515	molecular_function	protein binding
XD	0005886	cellular_component	plasma membrane
XD	0009408	biological_process	response to heat
XD	0016020	cellular_component	membrane
XD	0052547	biological_process	regulation of peptidase activity
XD	0098796	cellular_component	membrane protein complex
XD	0098797	cellular_component	plasma membrane protein complex
XE	0005515	molecular_function	protein binding
XE	0005829	cellular_component	cytosol
XE	0005886	cellular_component	plasma membrane
XE	0009408	biological_process	response to heat
XE	0016020	cellular_component	membrane
XE	0098796	cellular_component	membrane protein complex
XF	0005515	molecular_function	protein binding
XF	0005886	cellular_component	plasma membrane
XF	0009408	biological_process	response to heat
XF	0016020	cellular_component	membrane
XF	0052547	biological_process	regulation of peptidase activity
XF	0098796	cellular_component	membrane protein complex
XF	0098797	cellular_component	plasma membrane protein complex
XG	0005515	molecular_function	protein binding
XG	0005829	cellular_component	cytosol
XG	0005886	cellular_component	plasma membrane
XG	0009408	biological_process	response to heat
XG	0016020	cellular_component	membrane
XG	0098796	cellular_component	membrane protein complex
XH	0005515	molecular_function	protein binding
XH	0005886	cellular_component	plasma membrane
XH	0009408	biological_process	response to heat
XH	0016020	cellular_component	membrane
XH	0052547	biological_process	regulation of peptidase activity
XH	0098796	cellular_component	membrane protein complex
XH	0098797	cellular_component	plasma membrane protein complex
XI	0005515	molecular_function	protein binding
XI	0005829	cellular_component	cytosol
XI	0005886	cellular_component	plasma membrane
XI	0009408	biological_process	response to heat
XI	0016020	cellular_component	membrane
XI	0098796	cellular_component	membrane protein complex
XJ	0005515	molecular_function	protein binding
XJ	0005886	cellular_component	plasma membrane
XJ	0009408	biological_process	response to heat
XJ	0016020	cellular_component	membrane
XJ	0052547	biological_process	regulation of peptidase activity
XJ	0098796	cellular_component	membrane protein complex
XJ	0098797	cellular_component	plasma membrane protein complex
XK	0005515	molecular_function	protein binding
XK	0005829	cellular_component	cytosol
XK	0005886	cellular_component	plasma membrane
XK	0009408	biological_process	response to heat
XK	0016020	cellular_component	membrane
XK	0098796	cellular_component	membrane protein complex
XL	0005515	molecular_function	protein binding
XL	0005886	cellular_component	plasma membrane
XL	0009408	biological_process	response to heat
XL	0016020	cellular_component	membrane
XL	0052547	biological_process	regulation of peptidase activity
XL	0098796	cellular_component	membrane protein complex
XL	0098797	cellular_component	plasma membrane protein complex
XM	0005515	molecular_function	protein binding
XM	0005829	cellular_component	cytosol
XM	0005886	cellular_component	plasma membrane
XM	0009408	biological_process	response to heat
XM	0016020	cellular_component	membrane
XM	0098796	cellular_component	membrane protein complex
XN	0005515	molecular_function	protein binding
XN	0005886	cellular_component	plasma membrane
XN	0009408	biological_process	response to heat
XN	0016020	cellular_component	membrane
XN	0052547	biological_process	regulation of peptidase activity
XN	0098796	cellular_component	membrane protein complex
XN	0098797	cellular_component	plasma membrane protein complex
XO	0005515	molecular_function	protein binding
XO	0005829	cellular_component	cytosol
XO	0005886	cellular_component	plasma membrane
XO	0009408	biological_process	response to heat
XO	0016020	cellular_component	membrane
XO	0098796	cellular_component	membrane protein complex
XP	0005515	molecular_function	protein binding
XP	0005886	cellular_component	plasma membrane
XP	0009408	biological_process	response to heat
XP	0016020	cellular_component	membrane
XP	0052547	biological_process	regulation of peptidase activity
XP	0098796	cellular_component	membrane protein complex
XP	0098797	cellular_component	plasma membrane protein complex
XQ	0005515	molecular_function	protein binding
XQ	0005829	cellular_component	cytosol
XQ	0005886	cellular_component	plasma membrane
XQ	0009408	biological_process	response to heat
XQ	0016020	cellular_component	membrane
XQ	0098796	cellular_component	membrane protein complex
XR	0005515	molecular_function	protein binding
XR	0005886	cellular_component	plasma membrane
XR	0009408	biological_process	response to heat
XR	0016020	cellular_component	membrane
XR	0052547	biological_process	regulation of peptidase activity
XR	0098796	cellular_component	membrane protein complex
XR	0098797	cellular_component	plasma membrane protein complex
XS	0005515	molecular_function	protein binding
XS	0005829	cellular_component	cytosol
XS	0005886	cellular_component	plasma membrane
XS	0009408	biological_process	response to heat
XS	0016020	cellular_component	membrane
XS	0098796	cellular_component	membrane protein complex
XT	0005515	molecular_function	protein binding
XT	0005886	cellular_component	plasma membrane
XT	0009408	biological_process	response to heat
XT	0016020	cellular_component	membrane
XT	0052547	biological_process	regulation of peptidase activity
XT	0098796	cellular_component	membrane protein complex
XT	0098797	cellular_component	plasma membrane protein complex
XU	0005515	molecular_function	protein binding
XU	0005829	cellular_component	cytosol
XU	0005886	cellular_component	plasma membrane
XU	0009408	biological_process	response to heat
XU	0016020	cellular_component	membrane
XU	0098796	cellular_component	membrane protein complex
XV	0005515	molecular_function	protein binding
XV	0005886	cellular_component	plasma membrane
XV	0009408	biological_process	response to heat
XV	0016020	cellular_component	membrane
XV	0052547	biological_process	regulation of peptidase activity
XV	0098796	cellular_component	membrane protein complex
XV	0098797	cellular_component	plasma membrane protein complex
XW	0005515	molecular_function	protein binding
XW	0005829	cellular_component	cytosol
XW	0005886	cellular_component	plasma membrane
XW	0009408	biological_process	response to heat
XW	0016020	cellular_component	membrane
XW	0098796	cellular_component	membrane protein complex
XX	0005515	molecular_function	protein binding
XX	0005886	cellular_component	plasma membrane
XX	0009408	biological_process	response to heat
XX	0016020	cellular_component	membrane
XX	0052547	biological_process	regulation of peptidase activity
XX	0098796	cellular_component	membrane protein complex
XX	0098797	cellular_component	plasma membrane protein complex

Functional Information from PROSITE/UniProt

site_id	PS00674
Number of Residues	19
Details	AAA AAA-protein family signature. IiVIaATNrpdvLDpALl.R

Chain	Residue	Details
C	ILE291-ARG309

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	420
Details	Transmembrane: {"description":"Helical; Signal-anchor for type II membrane protein","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	10
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"9159109","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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