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9CTT

Best1 + GABA closed state

Functional Information from GO Data
ChainGOidnamespacecontents
A0005229molecular_functionintracellularly calcium-gated chloride channel activity
A0005254molecular_functionchloride channel activity
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006821biological_processchloride transport
A0007601biological_processvisual perception
A0009925cellular_componentbasal plasma membrane
A0014047biological_processglutamate secretion
A0015106molecular_functionbicarbonate transmembrane transporter activity
A0015267molecular_functionchannel activity
A0015701biological_processbicarbonate transport
A0016020cellular_componentmembrane
A0016323cellular_componentbasolateral plasma membrane
A0022834molecular_functionligand-gated channel activity
A0030321biological_processtransepithelial chloride transport
A0034220biological_processmonoatomic ion transmembrane transport
A0034707cellular_componentchloride channel complex
A0042802molecular_functionidentical protein binding
A0048167biological_processregulation of synaptic plasticity
A0050908biological_processdetection of light stimulus involved in visual perception
A0051259biological_processprotein complex oligomerization
A0051924biological_processregulation of calcium ion transport
A0061534biological_processgamma-aminobutyric acid secretion, neurotransmission
A0098793cellular_componentpresynapse
A0098857cellular_componentmembrane microdomain
A0160133molecular_functionbicarbonate channel activity
A1902476biological_processchloride transmembrane transport
B0005229molecular_functionintracellularly calcium-gated chloride channel activity
B0005254molecular_functionchloride channel activity
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006821biological_processchloride transport
B0007601biological_processvisual perception
B0009925cellular_componentbasal plasma membrane
B0014047biological_processglutamate secretion
B0015106molecular_functionbicarbonate transmembrane transporter activity
B0015267molecular_functionchannel activity
B0015701biological_processbicarbonate transport
B0016020cellular_componentmembrane
B0016323cellular_componentbasolateral plasma membrane
B0022834molecular_functionligand-gated channel activity
B0030321biological_processtransepithelial chloride transport
B0034220biological_processmonoatomic ion transmembrane transport
B0034707cellular_componentchloride channel complex
B0042802molecular_functionidentical protein binding
B0048167biological_processregulation of synaptic plasticity
B0050908biological_processdetection of light stimulus involved in visual perception
B0051259biological_processprotein complex oligomerization
B0051924biological_processregulation of calcium ion transport
B0061534biological_processgamma-aminobutyric acid secretion, neurotransmission
B0098793cellular_componentpresynapse
B0098857cellular_componentmembrane microdomain
B0160133molecular_functionbicarbonate channel activity
B1902476biological_processchloride transmembrane transport
C0005229molecular_functionintracellularly calcium-gated chloride channel activity
C0005254molecular_functionchloride channel activity
C0005829cellular_componentcytosol
C0005886cellular_componentplasma membrane
C0006821biological_processchloride transport
C0007601biological_processvisual perception
C0009925cellular_componentbasal plasma membrane
C0014047biological_processglutamate secretion
C0015106molecular_functionbicarbonate transmembrane transporter activity
C0015267molecular_functionchannel activity
C0015701biological_processbicarbonate transport
C0016020cellular_componentmembrane
C0016323cellular_componentbasolateral plasma membrane
C0022834molecular_functionligand-gated channel activity
C0030321biological_processtransepithelial chloride transport
C0034220biological_processmonoatomic ion transmembrane transport
C0034707cellular_componentchloride channel complex
C0042802molecular_functionidentical protein binding
C0048167biological_processregulation of synaptic plasticity
C0050908biological_processdetection of light stimulus involved in visual perception
C0051259biological_processprotein complex oligomerization
C0051924biological_processregulation of calcium ion transport
C0061534biological_processgamma-aminobutyric acid secretion, neurotransmission
C0098793cellular_componentpresynapse
C0098857cellular_componentmembrane microdomain
C0160133molecular_functionbicarbonate channel activity
C1902476biological_processchloride transmembrane transport
D0005229molecular_functionintracellularly calcium-gated chloride channel activity
D0005254molecular_functionchloride channel activity
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0006821biological_processchloride transport
D0007601biological_processvisual perception
D0009925cellular_componentbasal plasma membrane
D0014047biological_processglutamate secretion
D0015106molecular_functionbicarbonate transmembrane transporter activity
D0015267molecular_functionchannel activity
D0015701biological_processbicarbonate transport
D0016020cellular_componentmembrane
D0016323cellular_componentbasolateral plasma membrane
D0022834molecular_functionligand-gated channel activity
D0030321biological_processtransepithelial chloride transport
D0034220biological_processmonoatomic ion transmembrane transport
D0034707cellular_componentchloride channel complex
D0042802molecular_functionidentical protein binding
D0048167biological_processregulation of synaptic plasticity
D0050908biological_processdetection of light stimulus involved in visual perception
D0051259biological_processprotein complex oligomerization
D0051924biological_processregulation of calcium ion transport
D0061534biological_processgamma-aminobutyric acid secretion, neurotransmission
D0098793cellular_componentpresynapse
D0098857cellular_componentmembrane microdomain
D0160133molecular_functionbicarbonate channel activity
D1902476biological_processchloride transmembrane transport
E0005229molecular_functionintracellularly calcium-gated chloride channel activity
E0005254molecular_functionchloride channel activity
E0005829cellular_componentcytosol
E0005886cellular_componentplasma membrane
E0006821biological_processchloride transport
E0007601biological_processvisual perception
E0009925cellular_componentbasal plasma membrane
E0014047biological_processglutamate secretion
E0015106molecular_functionbicarbonate transmembrane transporter activity
E0015267molecular_functionchannel activity
E0015701biological_processbicarbonate transport
E0016020cellular_componentmembrane
E0016323cellular_componentbasolateral plasma membrane
E0022834molecular_functionligand-gated channel activity
E0030321biological_processtransepithelial chloride transport
E0034220biological_processmonoatomic ion transmembrane transport
E0034707cellular_componentchloride channel complex
E0042802molecular_functionidentical protein binding
E0048167biological_processregulation of synaptic plasticity
E0050908biological_processdetection of light stimulus involved in visual perception
E0051259biological_processprotein complex oligomerization
E0051924biological_processregulation of calcium ion transport
E0061534biological_processgamma-aminobutyric acid secretion, neurotransmission
E0098793cellular_componentpresynapse
E0098857cellular_componentmembrane microdomain
E0160133molecular_functionbicarbonate channel activity
E1902476biological_processchloride transmembrane transport
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues350
DetailsTRANSMEM: Helical => ECO:0000269|PubMed:17110374, ECO:0000269|PubMed:35789156
ChainResidueDetails
DLEU32-ARG51
EMET61-LEU82
EGLN238-ARG255
EVAL275-LEU288
ALEU32-ARG51
AMET61-LEU82
AGLN238-ARG255
AVAL275-LEU288
CLEU32-ARG51
CMET61-LEU82
CGLN238-ARG255
DMET61-LEU82
CVAL275-LEU288
DGLN238-ARG255
DVAL275-LEU288
BLEU32-ARG51
BMET61-LEU82
BGLN238-ARG255
BVAL275-LEU288
ELEU32-ARG51

site_idSWS_FT_FI2
Number of Residues130
DetailsTOPO_DOM: Extracellular => ECO:0000305|PubMed:12907679
ChainResidueDetails
DLEU52-LEU60
CGLN256-PRO274
DGLN256-PRO274
BLEU52-LEU60
BGLN256-PRO274
ELEU52-LEU60
EGLN256-PRO274
ALEU52-LEU60
AGLN256-PRO274
CLEU52-LEU60

site_idSWS_FT_FI3
Number of Residues770
DetailsTOPO_DOM: Cytoplasmic => ECO:0000255
ChainResidueDetails
DGLY83-THR237
BGLY83-THR237
EGLY83-THR237
AGLY83-THR237
CGLY83-THR237

site_idSWS_FT_FI4
Number of Residues1480
DetailsTOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:12907679
ChainResidueDetails
DLYS289-SER585
BLYS289-SER585
ELYS289-SER585
ALYS289-SER585
CLYS289-SER585

site_idSWS_FT_FI5
Number of Residues5
DetailsBINDING: in other chain => ECO:0000269|PubMed:35789156, ECO:0007744|PDB:8D1I, ECO:0007744|PDB:8D1J, ECO:0007744|PDB:8D1K, ECO:0007744|PDB:8D1L, ECO:0007744|PDB:8D1O
ChainResidueDetails
DALA10
BALA10
EALA10
AALA10
CALA10

site_idSWS_FT_FI6
Number of Residues20
DetailsBINDING: BINDING => ECO:0000269|PubMed:35789156, ECO:0007744|PDB:8D1I, ECO:0007744|PDB:8D1J, ECO:0007744|PDB:8D1K, ECO:0007744|PDB:8D1L, ECO:0007744|PDB:8D1O
ChainResidueDetails
DGLN293
EASN296
EASP301
EASP304
AGLN293
AASN296
AASP301
AASP304
CGLN293
CASN296
CASP301
DASN296
CASP304
DASP301
DASP304
BGLN293
BASN296
BASP301
BASP304
EGLN293

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PDB entries from 2024-11-06

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