9CPF
Structural basis of BAK sequestration by MCL-1 and consequences for apoptosis initiation
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008643 | biological_process | carbohydrate transport |
| A | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| A | 0042981 | biological_process | regulation of apoptotic process |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0008643 | biological_process | carbohydrate transport |
| B | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| B | 0042981 | biological_process | regulation of apoptotic process |
| B | 0055085 | biological_process | transmembrane transport |
| C | 0008643 | biological_process | carbohydrate transport |
| C | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| C | 0042981 | biological_process | regulation of apoptotic process |
| C | 0055085 | biological_process | transmembrane transport |
| D | 0008643 | biological_process | carbohydrate transport |
| D | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| D | 0042981 | biological_process | regulation of apoptotic process |
| D | 0055085 | biological_process | transmembrane transport |
Functional Information from PROSITE/UniProt
| site_id | PS01037 |
| Number of Residues | 18 |
| Details | SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN |
| Chain | Residue | Details |
| A | PRO911-ASN928 |
| site_id | PS01080 |
| Number of Residues | 20 |
| Details | BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. VFsDGvtNWGRIVTLIsFGA |
| Chain | Residue | Details |
| A | VAL1253-ALA1272 |
| site_id | PS01258 |
| Number of Residues | 12 |
| Details | BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WLvkqRGWDgFV |
| Chain | Residue | Details |
| A | TRP1305-VAL1316 |
| site_id | PS01259 |
| Number of Residues | 15 |
| Details | BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. AgrqLAiIGDDINRR |
| Chain | Residue | Details |
| E | ALA74-ARG88 | |
| A | ALA1209-ASN1223 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 56 |
| Details | Motif: {"description":"BH3"} |
| Chain | Residue | Details |
