9CMZ

Crystal Structure of Cdk-related protein kinase 6 (PK6) from Plasmodium falciparum in complex with inhibitor KG2-051

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004672	molecular_function	protein kinase activity
A	0004674	molecular_function	protein serine/threonine kinase activity
A	0004693	molecular_function	cyclin-dependent protein serine/threonine kinase activity
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0006357	biological_process	regulation of transcription by RNA polymerase II
A	0006468	biological_process	protein phosphorylation
A	0008353	molecular_function	RNA polymerase II CTD heptapeptide repeat kinase activity
A	0016301	molecular_function	kinase activity
A	0016592	cellular_component	mediator complex
A	0016740	molecular_function	transferase activity
A	0051726	biological_process	regulation of cell cycle
A	0106310	molecular_function	protein serine kinase activity
B	0000166	molecular_function	nucleotide binding
B	0004672	molecular_function	protein kinase activity
B	0004674	molecular_function	protein serine/threonine kinase activity
B	0004693	molecular_function	cyclin-dependent protein serine/threonine kinase activity
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0006357	biological_process	regulation of transcription by RNA polymerase II
B	0006468	biological_process	protein phosphorylation
B	0008353	molecular_function	RNA polymerase II CTD heptapeptide repeat kinase activity
B	0016301	molecular_function	kinase activity
B	0016592	cellular_component	mediator complex
B	0016740	molecular_function	transferase activity
B	0051726	biological_process	regulation of cell cycle
B	0106310	molecular_function	protein serine kinase activity
C	0000166	molecular_function	nucleotide binding
C	0004672	molecular_function	protein kinase activity
C	0004674	molecular_function	protein serine/threonine kinase activity
C	0004693	molecular_function	cyclin-dependent protein serine/threonine kinase activity
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0006357	biological_process	regulation of transcription by RNA polymerase II
C	0006468	biological_process	protein phosphorylation
C	0008353	molecular_function	RNA polymerase II CTD heptapeptide repeat kinase activity
C	0016301	molecular_function	kinase activity
C	0016592	cellular_component	mediator complex
C	0016740	molecular_function	transferase activity
C	0051726	biological_process	regulation of cell cycle
C	0106310	molecular_function	protein serine kinase activity

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	25
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGKGTYGIVYkAldkkennfv.........AIKK

Chain	Residue	Details
A	ILE15-LYS39

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site_id	PS00108
Number of Residues	13
Details	PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. YiHrDIKpeNIFI

Chain	Residue	Details
A	TYR139-ILE151

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