9CME
Room Temperature Crystal Structure of Collagenase ColH from Hathewaya histolytica at 2.7 Angstrom resolution
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. LFRHEYTHYL |
| Chain | Residue | Details |
| A | LEU412-LEU421 |
| site_id | PS00216 |
| Number of Residues | 16 |
| Details | SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. MSFIMDEIGRRapqy..T |
| Chain | Residue | Details |
| A | MET53-THR68 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 271 |
| Details | Region: {"description":"Catalytic subdomain","evidences":[{"source":"PubMed","id":"23703618","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 112 |
| Details | Region: {"description":"Helper subdomain","evidences":[{"source":"PubMed","id":"23703618","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10095","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"9452493","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23703618","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4AR1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23703618","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28820255","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4AR1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ARF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5O7E","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10095","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23703618","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28820255","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10217773","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"4AR1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ARF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5O7E","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23703618","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28820255","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10217773","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"4AR1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ARF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5O7E","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
