9CHN
P. vulgaris trimeric HigBA- operator 2 DNA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0046982 | molecular_function | protein heterodimerization activity |
| A | 0097351 | molecular_function | toxin sequestering activity |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003729 | molecular_function | mRNA binding |
| B | 0004518 | molecular_function | nuclease activity |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0004521 | molecular_function | RNA endonuclease activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0006276 | biological_process | plasmid maintenance |
| B | 0006401 | biological_process | RNA catabolic process |
| B | 0008285 | biological_process | negative regulation of cell population proliferation |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0017148 | biological_process | negative regulation of translation |
| B | 0030308 | biological_process | negative regulation of cell growth |
| B | 0030371 | molecular_function | translation repressor activity |
| B | 0043022 | molecular_function | ribosome binding |
| C | 0000976 | molecular_function | transcription cis-regulatory region binding |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0006351 | biological_process | DNA-templated transcription |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0046982 | molecular_function | protein heterodimerization activity |
| C | 0097351 | molecular_function | toxin sequestering activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 201 |
| Chain | Residue |
| A | LEU90 |
| A | GLY92 |
| A | HOH306 |
| A | HOH307 |
| A | HOH312 |
| D | DC21 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 202 |
| Chain | Residue |
| D | DA13 |
| D | HOH206 |
| D | HOH209 |
| A | LYS45 |
| A | HOH320 |
| A | HOH328 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 101 |
| Chain | Residue |
| B | MET0 |
| B | ASP38 |
| B | HOH202 |
| B | HOH204 |
| B | HOH205 |
| C | HOH230 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue MG D 101 |
| Chain | Residue |
| D | HOH220 |
| D | HOH233 |
| E | HOH204 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue MG D 102 |
| Chain | Residue |
| D | HOH227 |
| D | HOH234 |
| D | HOH240 |
| E | HOH233 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue MG E 101 |
| Chain | Residue |
| D | HOH214 |
| D | HOH239 |
| E | HOH230 |
| E | HOH243 |
| E | HOH244 |
| E | HOH246 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue MG E 102 |
| Chain | Residue |
| D | HOH218 |
| D | HOH232 |
| E | HOH220 |
| E | HOH240 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue MG E 103 |
| Chain | Residue |
| E | HOH239 |
| E | HOH248 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue MG E 104 |
| Chain | Residue |
| D | HOH213 |
| D | HOH231 |
| D | HOH241 |
| D | HOH242 |
| E | HOH221 |
| E | HOH235 |
| E | HOH247 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue MG E 105 |
| Chain | Residue |
| D | HOH212 |
| D | HOH229 |
| D | HOH238 |
| E | HOH222 |
| E | HOH234 |
| E | HOH238 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue MG E 106 |
| Chain | Residue |
| D | HOH235 |
| D | HOH236 |
| E | DG11 |
| E | DT12 |
| E | HOH241 |
| site_id | AD3 |
| Number of Residues | 1 |
| Details | binding site for residue MG E 107 |
| Chain | Residue |
| D | HOH223 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 108 |
| Details | Domain: {"description":"HTH cro/C1-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00257","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 38 |
| Details | DNA binding: {"description":"H-T-H motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00257","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"4MCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Interaction with HigB","evidences":[{"source":"PubMed","id":"24257752","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Interaction with HigA","evidences":[{"source":"PubMed","id":"24257752","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
