Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9CHL

P. vulgaris tetrameric HigBA- operator 2 DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005515	molecular_function	protein binding
A	0006351	biological_process	DNA-templated transcription
A	0006355	biological_process	regulation of DNA-templated transcription
A	0046982	molecular_function	protein heterodimerization activity
A	0097351	molecular_function	toxin sequestering activity
B	0003723	molecular_function	RNA binding
B	0003729	molecular_function	mRNA binding
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0004521	molecular_function	RNA endonuclease activity
B	0005515	molecular_function	protein binding
B	0006276	biological_process	plasmid maintenance
B	0006401	biological_process	RNA catabolic process
B	0008285	biological_process	negative regulation of cell population proliferation
B	0016787	molecular_function	hydrolase activity
B	0017148	biological_process	negative regulation of translation
B	0030308	biological_process	negative regulation of cell growth
B	0030371	molecular_function	translation repressor activity
B	0043022	molecular_function	ribosome binding
C	0000976	molecular_function	transcription cis-regulatory region binding
C	0003677	molecular_function	DNA binding
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0005515	molecular_function	protein binding
C	0006351	biological_process	DNA-templated transcription
C	0006355	biological_process	regulation of DNA-templated transcription
C	0046982	molecular_function	protein heterodimerization activity
C	0097351	molecular_function	toxin sequestering activity
D	0003723	molecular_function	RNA binding
D	0003729	molecular_function	mRNA binding
D	0004518	molecular_function	nuclease activity
D	0004519	molecular_function	endonuclease activity
D	0004521	molecular_function	RNA endonuclease activity
D	0005515	molecular_function	protein binding
D	0006276	biological_process	plasmid maintenance
D	0006401	biological_process	RNA catabolic process
D	0008285	biological_process	negative regulation of cell population proliferation
D	0016787	molecular_function	hydrolase activity
D	0017148	biological_process	negative regulation of translation
D	0030308	biological_process	negative regulation of cell growth
D	0030371	molecular_function	translation repressor activity
D	0043022	molecular_function	ribosome binding
E	0000976	molecular_function	transcription cis-regulatory region binding
E	0003677	molecular_function	DNA binding
E	0003700	molecular_function	DNA-binding transcription factor activity
E	0005515	molecular_function	protein binding
E	0006351	biological_process	DNA-templated transcription
E	0006355	biological_process	regulation of DNA-templated transcription
E	0046982	molecular_function	protein heterodimerization activity
E	0097351	molecular_function	toxin sequestering activity
F	0003723	molecular_function	RNA binding
F	0003729	molecular_function	mRNA binding
F	0004518	molecular_function	nuclease activity
F	0004519	molecular_function	endonuclease activity
F	0004521	molecular_function	RNA endonuclease activity
F	0005515	molecular_function	protein binding
F	0006276	biological_process	plasmid maintenance
F	0006401	biological_process	RNA catabolic process
F	0008285	biological_process	negative regulation of cell population proliferation
F	0016787	molecular_function	hydrolase activity
F	0017148	biological_process	negative regulation of translation
F	0030308	biological_process	negative regulation of cell growth
F	0030371	molecular_function	translation repressor activity
F	0043022	molecular_function	ribosome binding
G	0000976	molecular_function	transcription cis-regulatory region binding
G	0003677	molecular_function	DNA binding
G	0003700	molecular_function	DNA-binding transcription factor activity
G	0005515	molecular_function	protein binding
G	0006351	biological_process	DNA-templated transcription
G	0006355	biological_process	regulation of DNA-templated transcription
G	0046982	molecular_function	protein heterodimerization activity
G	0097351	molecular_function	toxin sequestering activity
H	0003723	molecular_function	RNA binding
H	0003729	molecular_function	mRNA binding
H	0004518	molecular_function	nuclease activity
H	0004519	molecular_function	endonuclease activity
H	0004521	molecular_function	RNA endonuclease activity
H	0005515	molecular_function	protein binding
H	0006276	biological_process	plasmid maintenance
H	0006401	biological_process	RNA catabolic process
H	0008285	biological_process	negative regulation of cell population proliferation
H	0016787	molecular_function	hydrolase activity
H	0017148	biological_process	negative regulation of translation
H	0030308	biological_process	negative regulation of cell growth
H	0030371	molecular_function	translation repressor activity
H	0043022	molecular_function	ribosome binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue MG A 201

Chain	Residue
A	HIS8
A	ALA47
H	LYS16
J	HOH211

site_id	AC2
Number of Residues	3
Details	binding site for residue CL B 101

Chain	Residue
B	SER4
B	PHE5
B	LYS11

site_id	AC3
Number of Residues	2
Details	binding site for residue MG B 102

Chain	Residue
B	GLU42
D	ASP82

site_id	AC4
Number of Residues	3
Details	binding site for residue CL C 201

Chain	Residue
C	HIS8
F	LYS16
I	HOH106

site_id	AC5
Number of Residues	4
Details	binding site for residue MG C 202

Chain	Residue
F	HOH218
J	HOH207
J	HOH228
J	HOH233

site_id	AC6
Number of Residues	3
Details	binding site for residue CL D 101

Chain	Residue
D	SER4
D	PHE5
D	LYS11

site_id	AC7
Number of Residues	2
Details	binding site for residue MG J 101

Chain	Residue
I	HOH125
J	DG10

site_id	AC8
Number of Residues	1
Details	binding site for residue MG J 102

Chain	Residue
I	HOH128

site_id	AC9
Number of Residues	3
Details	binding site for residue MG J 103

Chain	Residue
I	HOH110
J	HOH231
J	HOH232

site_id	AD1
Number of Residues	6
Details	binding site for residue MG E 201

Chain	Residue
C	HOH302
C	HOH311
E	THR85
E	SER86
E	ILE88
G	HOH313

site_id	AD2
Number of Residues	2
Details	binding site for residue CL F 101

Chain	Residue
F	PHE5
F	LYS11

site_id	AD3
Number of Residues	2
Details	binding site for residue MG H 101

Chain	Residue
F	ASP82
H	GLU42

site_id	AD4
Number of Residues	4
Details	binding site for residue MG G 201

Chain	Residue
B	LYS16
G	HIS8
G	ALA47
G	GLN71

site_id	AD5
Number of Residues	2
Details	binding site for residue MG G 202

Chain	Residue
B	HOH218
K	HOH219

site_id	AD6
Number of Residues	3
Details	binding site for residue CL H 102

Chain	Residue
H	SER4
H	PHE5
H	LYS11

site_id	AD7
Number of Residues	3
Details	binding site for residue MG K 101

Chain	Residue
K	HOH209
K	HOH222
L	HOH204

site_id	AD8
Number of Residues	1
Details	binding site for residue MG K 102

Chain	Residue
L	HOH221

site_id	AD9
Number of Residues	2
Details	binding site for residue MG L 101

Chain	Residue
G	HOH330
L	HOH214

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	76
Details	DNA binding: {"description":"H-T-H motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00257","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"4MCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	8
Details	Site: {"description":"Interaction with HigB","evidences":[{"source":"PubMed","id":"24257752","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	8
Details	Site: {"description":"Interaction with HigA","evidences":[{"source":"PubMed","id":"24257752","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)