9CGC

Yeast 26S proteasome non-substrate-engaged (S1 state)

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0000502	cellular_component	proteasome complex
1	0004175	molecular_function	endopeptidase activity
1	0004298	molecular_function	threonine-type endopeptidase activity
1	0005515	molecular_function	protein binding
1	0005634	cellular_component	nucleus
1	0005737	cellular_component	cytoplasm
1	0005829	cellular_component	cytosol
1	0006508	biological_process	proteolysis
1	0008233	molecular_function	peptidase activity
1	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
1	0016787	molecular_function	hydrolase activity
1	0019774	cellular_component	proteasome core complex, beta-subunit complex
1	0034515	cellular_component	proteasome storage granule
1	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
2	0000502	cellular_component	proteasome complex
2	0004175	molecular_function	endopeptidase activity
2	0004298	molecular_function	threonine-type endopeptidase activity
2	0005515	molecular_function	protein binding
2	0005634	cellular_component	nucleus
2	0005737	cellular_component	cytoplasm
2	0005829	cellular_component	cytosol
2	0006508	biological_process	proteolysis
2	0008233	molecular_function	peptidase activity
2	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
2	0016787	molecular_function	hydrolase activity
2	0019774	cellular_component	proteasome core complex, beta-subunit complex
2	0034515	cellular_component	proteasome storage granule
2	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
3	0000502	cellular_component	proteasome complex
3	0005515	molecular_function	protein binding
3	0005634	cellular_component	nucleus
3	0005737	cellular_component	cytoplasm
3	0005829	cellular_component	cytosol
3	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
3	0019774	cellular_component	proteasome core complex, beta-subunit complex
3	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
3	0061133	molecular_function	endopeptidase activator activity
4	0000502	cellular_component	proteasome complex
4	0005515	molecular_function	protein binding
4	0005634	cellular_component	nucleus
4	0005737	cellular_component	cytoplasm
4	0005789	cellular_component	endoplasmic reticulum membrane
4	0005829	cellular_component	cytosol
4	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
4	0019774	cellular_component	proteasome core complex, beta-subunit complex
4	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
4	0061133	molecular_function	endopeptidase activator activity
5	0000502	cellular_component	proteasome complex
5	0004175	molecular_function	endopeptidase activity
5	0004298	molecular_function	threonine-type endopeptidase activity
5	0005515	molecular_function	protein binding
5	0005634	cellular_component	nucleus
5	0005737	cellular_component	cytoplasm
5	0005777	cellular_component	peroxisome
5	0005829	cellular_component	cytosol
5	0006508	biological_process	proteolysis
5	0008233	molecular_function	peptidase activity
5	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
5	0016787	molecular_function	hydrolase activity
5	0019774	cellular_component	proteasome core complex, beta-subunit complex
5	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
5	0080129	biological_process	proteasome core complex assembly
6	0000502	cellular_component	proteasome complex
6	0003674	molecular_function	molecular_function
6	0005515	molecular_function	protein binding
6	0005634	cellular_component	nucleus
6	0005737	cellular_component	cytoplasm
6	0005829	cellular_component	cytosol
6	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
6	0019774	cellular_component	proteasome core complex, beta-subunit complex
6	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
7	0000502	cellular_component	proteasome complex
7	0003674	molecular_function	molecular_function
7	0005515	molecular_function	protein binding
7	0005634	cellular_component	nucleus
7	0005737	cellular_component	cytoplasm
7	0005829	cellular_component	cytosol
7	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
7	0019774	cellular_component	proteasome core complex, beta-subunit complex
7	0034515	cellular_component	proteasome storage granule
7	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
7	0043248	biological_process	proteasome assembly
A	0000502	cellular_component	proteasome complex
A	0003674	molecular_function	molecular_function
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
A	0019773	cellular_component	proteasome core complex, alpha-subunit complex
A	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
B	0000502	cellular_component	proteasome complex
B	0003674	molecular_function	molecular_function
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
B	0019773	cellular_component	proteasome core complex, alpha-subunit complex
B	0034515	cellular_component	proteasome storage granule
B	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
C	0000502	cellular_component	proteasome complex
C	0003674	molecular_function	molecular_function
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
C	0019773	cellular_component	proteasome core complex, alpha-subunit complex
C	0034515	cellular_component	proteasome storage granule
C	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
C	0080129	biological_process	proteasome core complex assembly
D	0000502	cellular_component	proteasome complex
D	0003674	molecular_function	molecular_function
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
D	0019773	cellular_component	proteasome core complex, alpha-subunit complex
D	0034515	cellular_component	proteasome storage granule
D	0042175	cellular_component	nuclear outer membrane-endoplasmic reticulum membrane network
D	0042802	molecular_function	identical protein binding
D	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
E	0000502	cellular_component	proteasome complex
E	0003674	molecular_function	molecular_function
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
E	0019773	cellular_component	proteasome core complex, alpha-subunit complex
E	0034515	cellular_component	proteasome storage granule
E	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
F	0000502	cellular_component	proteasome complex
F	0003674	molecular_function	molecular_function
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm
F	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
F	0019773	cellular_component	proteasome core complex, alpha-subunit complex
F	0034515	cellular_component	proteasome storage granule
F	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
G	0000502	cellular_component	proteasome complex
G	0003729	molecular_function	mRNA binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005737	cellular_component	cytoplasm
G	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
G	0019773	cellular_component	proteasome core complex, alpha-subunit complex
G	0034515	cellular_component	proteasome storage granule
G	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
H	0000166	molecular_function	nucleotide binding
H	0000502	cellular_component	proteasome complex
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0006511	biological_process	ubiquitin-dependent protein catabolic process
H	0008540	cellular_component	proteasome regulatory particle, base subcomplex
H	0010498	biological_process	proteasomal protein catabolic process
H	0010604	biological_process	positive regulation of macromolecule metabolic process
H	0016887	molecular_function	ATP hydrolysis activity
H	0031625	molecular_function	ubiquitin protein ligase binding
H	0036402	molecular_function	proteasome-activating activity
H	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
H	0045732	biological_process	positive regulation of protein catabolic process
H	0045899	biological_process	positive regulation of RNA polymerase II transcription preinitiation complex assembly
H	0070682	biological_process	proteasome regulatory particle assembly
H	0080090	biological_process	regulation of primary metabolic process
I	0000166	molecular_function	nucleotide binding
I	0000502	cellular_component	proteasome complex
I	0005515	molecular_function	protein binding
I	0005524	molecular_function	ATP binding
I	0005634	cellular_component	nucleus
I	0005737	cellular_component	cytoplasm
I	0006511	biological_process	ubiquitin-dependent protein catabolic process
I	0008540	cellular_component	proteasome regulatory particle, base subcomplex
I	0010498	biological_process	proteasomal protein catabolic process
I	0010604	biological_process	positive regulation of macromolecule metabolic process
I	0016887	molecular_function	ATP hydrolysis activity
I	0031503	biological_process	protein-containing complex localization
I	0036402	molecular_function	proteasome-activating activity
I	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
I	0043171	biological_process	peptide catabolic process
I	0045732	biological_process	positive regulation of protein catabolic process
I	0070651	biological_process	nonfunctional rRNA decay
I	0070682	biological_process	proteasome regulatory particle assembly
I	0080090	biological_process	regulation of primary metabolic process
J	0000166	molecular_function	nucleotide binding
J	0000502	cellular_component	proteasome complex
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005634	cellular_component	nucleus
J	0005737	cellular_component	cytoplasm
J	0006289	biological_process	nucleotide-excision repair
J	0006338	biological_process	chromatin remodeling
J	0008540	cellular_component	proteasome regulatory particle, base subcomplex
J	0010498	biological_process	proteasomal protein catabolic process
J	0010604	biological_process	positive regulation of macromolecule metabolic process
J	0019904	molecular_function	protein domain specific binding
J	0031625	molecular_function	ubiquitin protein ligase binding
J	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
J	0034515	cellular_component	proteasome storage granule
J	0036402	molecular_function	proteasome-activating activity
J	0042802	molecular_function	identical protein binding
J	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
J	0045899	biological_process	positive regulation of RNA polymerase II transcription preinitiation complex assembly
J	0070651	biological_process	nonfunctional rRNA decay
J	0070682	biological_process	proteasome regulatory particle assembly
J	0080090	biological_process	regulation of primary metabolic process
K	0000166	molecular_function	nucleotide binding
K	0000502	cellular_component	proteasome complex
K	0005515	molecular_function	protein binding
K	0005524	molecular_function	ATP binding
K	0005634	cellular_component	nucleus
K	0005737	cellular_component	cytoplasm
K	0006511	biological_process	ubiquitin-dependent protein catabolic process
K	0008540	cellular_component	proteasome regulatory particle, base subcomplex
K	0010498	biological_process	proteasomal protein catabolic process
K	0010604	biological_process	positive regulation of macromolecule metabolic process
K	0016887	molecular_function	ATP hydrolysis activity
K	0036402	molecular_function	proteasome-activating activity
K	0042802	molecular_function	identical protein binding
K	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
K	0045899	biological_process	positive regulation of RNA polymerase II transcription preinitiation complex assembly
K	0070682	biological_process	proteasome regulatory particle assembly
K	0080090	biological_process	regulation of primary metabolic process
L	0000166	molecular_function	nucleotide binding
L	0000502	cellular_component	proteasome complex
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0005634	cellular_component	nucleus
L	0006289	biological_process	nucleotide-excision repair
L	0008540	cellular_component	proteasome regulatory particle, base subcomplex
L	0010498	biological_process	proteasomal protein catabolic process
L	0010604	biological_process	positive regulation of macromolecule metabolic process
L	0016887	molecular_function	ATP hydrolysis activity
L	0019904	molecular_function	protein domain specific binding
L	0031625	molecular_function	ubiquitin protein ligase binding
L	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
L	0036402	molecular_function	proteasome-activating activity
L	0036503	biological_process	ERAD pathway
L	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
L	0045899	biological_process	positive regulation of RNA polymerase II transcription preinitiation complex assembly
L	0070682	biological_process	proteasome regulatory particle assembly
L	0080090	biological_process	regulation of primary metabolic process
M	0000166	molecular_function	nucleotide binding
M	0000502	cellular_component	proteasome complex
M	0005515	molecular_function	protein binding
M	0005524	molecular_function	ATP binding
M	0005634	cellular_component	nucleus
M	0005737	cellular_component	cytoplasm
M	0006511	biological_process	ubiquitin-dependent protein catabolic process
M	0008540	cellular_component	proteasome regulatory particle, base subcomplex
M	0010498	biological_process	proteasomal protein catabolic process
M	0010604	biological_process	positive regulation of macromolecule metabolic process
M	0016887	molecular_function	ATP hydrolysis activity
M	0036402	molecular_function	proteasome-activating activity
M	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
M	0045899	biological_process	positive regulation of RNA polymerase II transcription preinitiation complex assembly
M	0070682	biological_process	proteasome regulatory particle assembly
M	0080090	biological_process	regulation of primary metabolic process
N	0000502	cellular_component	proteasome complex
N	0004175	molecular_function	endopeptidase activity
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0006511	biological_process	ubiquitin-dependent protein catabolic process
N	0008540	cellular_component	proteasome regulatory particle, base subcomplex
N	0031625	molecular_function	ubiquitin protein ligase binding
N	0034515	cellular_component	proteasome storage granule
N	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
N	0043248	biological_process	proteasome assembly
O	0000502	cellular_component	proteasome complex
O	0005198	molecular_function	structural molecule activity
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005829	cellular_component	cytosol
O	0006511	biological_process	ubiquitin-dependent protein catabolic process
O	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
O	0034515	cellular_component	proteasome storage granule
O	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
O	0043248	biological_process	proteasome assembly
P	0000338	biological_process	protein deneddylation
P	0000502	cellular_component	proteasome complex
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005737	cellular_component	cytoplasm
P	0008180	cellular_component	COP9 signalosome
P	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
P	0034515	cellular_component	proteasome storage granule
P	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Q	0000502	cellular_component	proteasome complex
Q	0005198	molecular_function	structural molecule activity
Q	0005515	molecular_function	protein binding
Q	0006511	biological_process	ubiquitin-dependent protein catabolic process
Q	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
Q	0034515	cellular_component	proteasome storage granule
Q	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Q	0043248	biological_process	proteasome assembly
R	0000502	cellular_component	proteasome complex
R	0005198	molecular_function	structural molecule activity
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005838	cellular_component	proteasome regulatory particle
R	0006511	biological_process	ubiquitin-dependent protein catabolic process
R	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
R	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
S	0000502	cellular_component	proteasome complex
S	0003674	molecular_function	molecular_function
S	0005515	molecular_function	protein binding
S	0006511	biological_process	ubiquitin-dependent protein catabolic process
S	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
S	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
T	0000502	cellular_component	proteasome complex
T	0003674	molecular_function	molecular_function
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0006511	biological_process	ubiquitin-dependent protein catabolic process
T	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
T	0034515	cellular_component	proteasome storage granule
T	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
U	0000502	cellular_component	proteasome complex
U	0005515	molecular_function	protein binding
U	0006511	biological_process	ubiquitin-dependent protein catabolic process
U	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
U	0034515	cellular_component	proteasome storage granule
U	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
V	0000266	biological_process	mitochondrial fission
V	0000502	cellular_component	proteasome complex
V	0004843	molecular_function	cysteine-type deubiquitinase activity
V	0005515	molecular_function	protein binding
V	0005634	cellular_component	nucleus
V	0005739	cellular_component	mitochondrion
V	0005829	cellular_component	cytosol
V	0006508	biological_process	proteolysis
V	0008233	molecular_function	peptidase activity
V	0008234	molecular_function	cysteine-type peptidase activity
V	0008237	molecular_function	metallopeptidase activity
V	0008270	molecular_function	zinc ion binding
V	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
V	0016559	biological_process	peroxisome fission
V	0016579	biological_process	protein deubiquitination
V	0016787	molecular_function	hydrolase activity
V	0032436	biological_process	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
V	0034515	cellular_component	proteasome storage granule
V	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
V	0043248	biological_process	proteasome assembly
V	0046872	molecular_function	metal ion binding
V	0070628	molecular_function	proteasome binding
V	0140492	molecular_function	metal-dependent deubiquitinase activity
V	1902906	biological_process	proteasome storage granule assembly
W	0000502	cellular_component	proteasome complex
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005829	cellular_component	cytosol
W	0008540	cellular_component	proteasome regulatory particle, base subcomplex
W	0031593	molecular_function	polyubiquitin modification-dependent protein binding
W	0032436	biological_process	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
W	0036435	molecular_function	K48-linked polyubiquitin modification-dependent protein binding
W	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
W	0043248	biological_process	proteasome assembly
Y	0000502	cellular_component	proteasome complex
Y	0000724	biological_process	double-strand break repair via homologous recombination
Y	0003674	molecular_function	molecular_function
Y	0005515	molecular_function	protein binding
Y	0005829	cellular_component	cytosol
Y	0006406	biological_process	mRNA export from nucleus
Y	0006457	biological_process	protein folding
Y	0006511	biological_process	ubiquitin-dependent protein catabolic process
Y	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
Y	0030447	biological_process	filamentous growth
Y	0034515	cellular_component	proteasome storage granule
Y	0035753	biological_process	maintenance of DNA trinucleotide repeats
Y	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Y	0043248	biological_process	proteasome assembly
Y	0044183	molecular_function	protein folding chaperone
Y	0045944	biological_process	positive regulation of transcription by RNA polymerase II
Y	0051726	biological_process	regulation of cell cycle
Y	0060090	molecular_function	molecular adaptor activity
Y	0070390	cellular_component	transcription export complex 2
Y	0072742	biological_process	SAGA complex localization to transcription regulatory region
a	0000502	cellular_component	proteasome complex
a	0003674	molecular_function	molecular_function
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005737	cellular_component	cytoplasm
a	0005829	cellular_component	cytosol
a	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
a	0019774	cellular_component	proteasome core complex, beta-subunit complex
a	0034515	cellular_component	proteasome storage granule
a	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
a	0043248	biological_process	proteasome assembly
b	0000502	cellular_component	proteasome complex
b	0004175	molecular_function	endopeptidase activity
b	0004298	molecular_function	threonine-type endopeptidase activity
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0006508	biological_process	proteolysis
b	0008233	molecular_function	peptidase activity
b	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
b	0016787	molecular_function	hydrolase activity
b	0019774	cellular_component	proteasome core complex, beta-subunit complex
b	0034515	cellular_component	proteasome storage granule
b	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
e	0000502	cellular_component	proteasome complex
e	0003674	molecular_function	molecular_function
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005737	cellular_component	cytoplasm
e	0005829	cellular_component	cytosol
e	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
e	0019774	cellular_component	proteasome core complex, beta-subunit complex
e	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
f	0000502	cellular_component	proteasome complex
f	0004175	molecular_function	endopeptidase activity
f	0004298	molecular_function	threonine-type endopeptidase activity
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0005737	cellular_component	cytoplasm
f	0005777	cellular_component	peroxisome
f	0005829	cellular_component	cytosol
f	0006508	biological_process	proteolysis
f	0008233	molecular_function	peptidase activity
f	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
f	0016787	molecular_function	hydrolase activity
f	0019774	cellular_component	proteasome core complex, beta-subunit complex
f	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
f	0080129	biological_process	proteasome core complex assembly
g	0000502	cellular_component	proteasome complex
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005737	cellular_component	cytoplasm
g	0005789	cellular_component	endoplasmic reticulum membrane
g	0005829	cellular_component	cytosol
g	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
g	0019774	cellular_component	proteasome core complex, beta-subunit complex
g	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
g	0061133	molecular_function	endopeptidase activator activity
h	0000502	cellular_component	proteasome complex
h	0005515	molecular_function	protein binding
h	0005634	cellular_component	nucleus
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
h	0019774	cellular_component	proteasome core complex, beta-subunit complex
h	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
h	0061133	molecular_function	endopeptidase activator activity
i	0000502	cellular_component	proteasome complex
i	0004175	molecular_function	endopeptidase activity
i	0004298	molecular_function	threonine-type endopeptidase activity
i	0005515	molecular_function	protein binding
i	0005634	cellular_component	nucleus
i	0005737	cellular_component	cytoplasm
i	0005829	cellular_component	cytosol
i	0006508	biological_process	proteolysis
i	0008233	molecular_function	peptidase activity
i	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
i	0016787	molecular_function	hydrolase activity
i	0019774	cellular_component	proteasome core complex, beta-subunit complex
i	0034515	cellular_component	proteasome storage granule
i	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
o	0000502	cellular_component	proteasome complex
o	0004175	molecular_function	endopeptidase activity
o	0005515	molecular_function	protein binding
o	0005634	cellular_component	nucleus
o	0005737	cellular_component	cytoplasm
o	0005783	cellular_component	endoplasmic reticulum
o	0006511	biological_process	ubiquitin-dependent protein catabolic process
o	0008540	cellular_component	proteasome regulatory particle, base subcomplex
o	0030674	molecular_function	protein-macromolecule adaptor activity
o	0034515	cellular_component	proteasome storage granule
o	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process

Functional Information from PROSITE/UniProt

site_id	PS00387
Number of Residues	7
Details	PPASE Inorganic pyrophosphatase signature. DDDEIDV

Chain	Residue	Details
U	ASP243-VAL249

---

site_id	PS00388
Number of Residues	23
Details	PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YdgdtVtFSPtGRlfQVEYAleA

Chain	Residue	Details
F	TYR6-ALA28
G	TYR8-ALA30
A	TYR12-ALA34
D	TYR4-ALA26
E	TYR8-ALA30
B	TYR5-ALA27
C	TYR6-SER28

---

site_id	PS00674
Number of Residues	19
Details	AAA AAA-protein family signature. VkVImATNkietLDpALi.R

Chain	Residue	Details
I	VAL322-ARG340
H	ILE349-ARG367
J	ILE288-ARG306
K	VAL312-ARG330
M	VAL321-ARG339
L	THR321-ARG339

---

site_id	PS00854
Number of Residues	48
Details	PROTEASOME_BETA_1 Proteasome beta-type subunits signature. LGIrVqdSVILASSkavtrgisvlkdsdd.KtrqlsphtlmsfaGeaGD

Chain	Residue	Details
g	LEU5-ASP52
2	VAL33-ASP80
D	VAL34-ASP81
1	MET23-ASP70
f	LEU79-ASP126
C	ILE36-ASP83
3	VAL13-ASP59
e	LEU32-ASP79
7	ILE45-ASP92

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"9087403","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	20
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	9
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"17287358","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	35
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	863
Details	Domain: {"description":"PCI","evidences":[{"source":"PROSITE-ProRule","id":"PRU01185","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	33
Details	Repeat: {"description":"TPR"}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	270
Details	Domain: {"description":"MPN","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	13
Details	Motif: {"description":"JAMM motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	185
Details	Domain: {"description":"VWFA","evidences":[{"source":"PROSITE-ProRule","id":"PRU00219","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"12504901","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	65
Details	Repeat: {"description":"PC 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	74
Details	Repeat: {"description":"PC 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	68
Details	Repeat: {"description":"PC 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	74
Details	Repeat: {"description":"PC 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	65
Details	Repeat: {"description":"PC 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	66
Details	Repeat: {"description":"PC 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	66
Details	Repeat: {"description":"PC 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	34
Details	Repeat: {"description":"PC 8"}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	37
Details	Repeat: {"description":"PC 9"}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	36
Details	Repeat: {"description":"PC 10"}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"12504901","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	8
Details	M-CSA 177

Chain	Residue	Details
B	GLN30	covalently attached, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor
B	ALA46	activator, steric locator
B	GLU48	activator
B	SER62	activator, electrostatic stabiliser
B	SER76	electrostatic stabiliser
B	PRO158	activator, electrostatic stabiliser
B	THR195	activator, steric locator
B	GLU198	activator, electrostatic stabiliser

---

site_id	MCSA2
Number of Residues	8
Details	M-CSA 177

Chain

Residue

Details

---