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9CD9

Structure of type II-2 alpha-synuclein filament from multiple system atrophy

Functional Information from GO Data
ChainGOidnamespacecontents
E0000122biological_processnegative regulation of transcription by RNA polymerase II
E0000149molecular_functionSNARE binding
E0000287molecular_functionmagnesium ion binding
E0000976molecular_functiontranscription cis-regulatory region binding
E0001774biological_processmicroglial cell activation
E0001921biological_processpositive regulation of receptor recycling
E0001956biological_processpositive regulation of neurotransmitter secretion
E0001963biological_processsynaptic transmission, dopaminergic
E0003779molecular_functionactin binding
E0004857molecular_functionenzyme inhibitor activity
E0004860molecular_functionprotein kinase inhibitor activity
E0004869molecular_functioncysteine-type endopeptidase inhibitor activity
E0005504molecular_functionfatty acid binding
E0005507molecular_functioncopper ion binding
E0005509molecular_functioncalcium ion binding
E0005515molecular_functionprotein binding
E0005543molecular_functionphospholipid binding
E0005576cellular_componentextracellular region
E0005615cellular_componentextracellular space
E0005634cellular_componentnucleus
E0005640cellular_componentnuclear outer membrane
E0005737cellular_componentcytoplasm
E0005739cellular_componentmitochondrion
E0005741cellular_componentmitochondrial outer membrane
E0005743cellular_componentmitochondrial inner membrane
E0005759cellular_componentmitochondrial matrix
E0005764cellular_componentlysosome
E0005829cellular_componentcytosol
E0005840cellular_componentribosome
E0005856cellular_componentcytoskeleton
E0005886cellular_componentplasma membrane
E0005938cellular_componentcell cortex
E0006631biological_processfatty acid metabolic process
E0006638biological_processneutral lipid metabolic process
E0006644biological_processphospholipid metabolic process
E0006749biological_processglutathione metabolic process
E0007006biological_processmitochondrial membrane organization
E0007268biological_processchemical synaptic transmission
E0007269biological_processneurotransmitter secretion
E0008017molecular_functionmicrotubule binding
E0008021cellular_componentsynaptic vesicle
E0008047molecular_functionenzyme activator activity
E0008198molecular_functionferrous iron binding
E0008270molecular_functionzinc ion binding
E0008289molecular_functionlipid binding
E0008344biological_processadult locomotory behavior
E0009410biological_processresponse to xenobiotic stimulus
E0010040biological_processresponse to iron(II) ion
E0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
E0014048biological_processregulation of glutamate secretion
E0014059biological_processregulation of dopamine secretion
E0015629cellular_componentactin cytoskeleton
E0016020cellular_componentmembrane
E0016079biological_processsynaptic vesicle exocytosis
E0016082biological_processsynaptic vesicle priming
E0016234cellular_componentinclusion body
E0016491molecular_functionoxidoreductase activity
E0019894molecular_functionkinesin binding
E0019899molecular_functionenzyme binding
E0019904molecular_functionprotein domain specific binding
E0030424cellular_componentaxon
E0030426cellular_componentgrowth cone
E0030544molecular_functionHsp70 protein binding
E0030659cellular_componentcytoplasmic vesicle membrane
E0030672cellular_componentsynaptic vesicle membrane
E0031092cellular_componentplatelet alpha granule membrane
E0031115biological_processnegative regulation of microtubule polymerization
E0031623biological_processreceptor internalization
E0031648biological_processprotein destabilization
E0032026biological_processresponse to magnesium ion
E0032496biological_processresponse to lipopolysaccharide
E0032991cellular_componentprotein-containing complex
E0034341biological_processresponse to type II interferon
E0034599biological_processcellular response to oxidative stress
E0035493biological_processSNARE complex assembly
E0035543biological_processpositive regulation of SNARE complex assembly
E0040012biological_processregulation of locomotion
E0042220biological_processresponse to cocaine
E0042393molecular_functionhistone binding
E0042416biological_processdopamine biosynthetic process
E0042417biological_processdopamine metabolic process
E0042775biological_processmitochondrial ATP synthesis coupled electron transport
E0042802molecular_functionidentical protein binding
E0042995cellular_componentcell projection
E0043014molecular_functionalpha-tubulin binding
E0043025cellular_componentneuronal cell body
E0043030biological_processregulation of macrophage activation
E0043065biological_processpositive regulation of apoptotic process
E0043066biological_processnegative regulation of apoptotic process
E0043195cellular_componentterminal bouton
E0043274molecular_functionphospholipase binding
E0043524biological_processnegative regulation of neuron apoptotic process
E0043679cellular_componentaxon terminus
E0044344biological_processcellular response to fibroblast growth factor stimulus
E0045202cellular_componentsynapse
E0045807biological_processpositive regulation of endocytosis
E0045920biological_processnegative regulation of exocytosis
E0045921biological_processpositive regulation of exocytosis
E0045963biological_processnegative regulation of dopamine metabolic process
E0046872molecular_functionmetal ion binding
E0046928biological_processregulation of neurotransmitter secretion
E0048148biological_processbehavioral response to cocaine
E0048156molecular_functiontau protein binding
E0048168biological_processregulation of neuronal synaptic plasticity
E0048169biological_processregulation of long-term neuronal synaptic plasticity
E0048471cellular_componentperinuclear region of cytoplasm
E0048487molecular_functionbeta-tubulin binding
E0048488biological_processsynaptic vesicle endocytosis
E0048489biological_processsynaptic vesicle transport
E0050729biological_processpositive regulation of inflammatory response
E0050806biological_processpositive regulation of synaptic transmission
E0050808biological_processsynapse organization
E0050812biological_processregulation of acyl-CoA biosynthetic process
E0051219molecular_functionphosphoprotein binding
E0051259biological_processprotein complex oligomerization
E0051262biological_processprotein tetramerization
E0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
E0051402biological_processneuron apoptotic process
E0051583biological_processdopamine uptake involved in synaptic transmission
E0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
E0051612biological_processnegative regulation of serotonin uptake
E0051621biological_processregulation of norepinephrine uptake
E0051622biological_processnegative regulation of norepinephrine uptake
E0055074biological_processcalcium ion homeostasis
E0060079biological_processexcitatory postsynaptic potential
E0060090molecular_functionmolecular adaptor activity
E0060291biological_processlong-term synaptic potentiation
E0060732biological_processpositive regulation of inositol phosphate biosynthetic process
E0060961molecular_functionphospholipase D inhibitor activity
E0061024biological_processmembrane organization
E0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
E0070507biological_processregulation of microtubule cytoskeleton organization
E0070555biological_processresponse to interleukin-1
E0070840molecular_functiondynein complex binding
E0071280biological_processcellular response to copper ion
E0071872biological_processcellular response to epinephrine stimulus
E0097435biological_processsupramolecular fiber organization
E0098793cellular_componentpresynapse
E0098794cellular_componentpostsynapse
E0099512cellular_componentsupramolecular fiber
E0140311molecular_functionprotein sequestering activity
E0141108molecular_functiontransporter regulator activity
E1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
E1903136molecular_functioncuprous ion binding
E1903285biological_processpositive regulation of hydrogen peroxide catabolic process
E1903421biological_processregulation of synaptic vesicle recycling
E1903426biological_processregulation of reactive oxygen species biosynthetic process
E1904307biological_processresponse to desipramine
E1904377biological_processpositive regulation of protein localization to cell periphery
E1904715biological_processnegative regulation of chaperone-mediated autophagy
E1905606biological_processregulation of presynapse assembly
E1990000biological_processamyloid fibril formation
E2000377biological_processregulation of reactive oxygen species metabolic process
F0000122biological_processnegative regulation of transcription by RNA polymerase II
F0000149molecular_functionSNARE binding
F0000287molecular_functionmagnesium ion binding
F0000976molecular_functiontranscription cis-regulatory region binding
F0001774biological_processmicroglial cell activation
F0001921biological_processpositive regulation of receptor recycling
F0001956biological_processpositive regulation of neurotransmitter secretion
F0001963biological_processsynaptic transmission, dopaminergic
F0003779molecular_functionactin binding
F0004857molecular_functionenzyme inhibitor activity
F0004860molecular_functionprotein kinase inhibitor activity
F0004869molecular_functioncysteine-type endopeptidase inhibitor activity
F0005504molecular_functionfatty acid binding
F0005507molecular_functioncopper ion binding
F0005509molecular_functioncalcium ion binding
F0005515molecular_functionprotein binding
F0005543molecular_functionphospholipid binding
F0005576cellular_componentextracellular region
F0005615cellular_componentextracellular space
F0005634cellular_componentnucleus
F0005640cellular_componentnuclear outer membrane
F0005737cellular_componentcytoplasm
F0005739cellular_componentmitochondrion
F0005741cellular_componentmitochondrial outer membrane
F0005743cellular_componentmitochondrial inner membrane
F0005759cellular_componentmitochondrial matrix
F0005764cellular_componentlysosome
F0005829cellular_componentcytosol
F0005840cellular_componentribosome
F0005856cellular_componentcytoskeleton
F0005886cellular_componentplasma membrane
F0005938cellular_componentcell cortex
F0006631biological_processfatty acid metabolic process
F0006638biological_processneutral lipid metabolic process
F0006644biological_processphospholipid metabolic process
F0006749biological_processglutathione metabolic process
F0007006biological_processmitochondrial membrane organization
F0007268biological_processchemical synaptic transmission
F0007269biological_processneurotransmitter secretion
F0008017molecular_functionmicrotubule binding
F0008021cellular_componentsynaptic vesicle
F0008047molecular_functionenzyme activator activity
F0008198molecular_functionferrous iron binding
F0008270molecular_functionzinc ion binding
F0008289molecular_functionlipid binding
F0008344biological_processadult locomotory behavior
F0009410biological_processresponse to xenobiotic stimulus
F0010040biological_processresponse to iron(II) ion
F0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
F0014048biological_processregulation of glutamate secretion
F0014059biological_processregulation of dopamine secretion
F0015629cellular_componentactin cytoskeleton
F0016020cellular_componentmembrane
F0016079biological_processsynaptic vesicle exocytosis
F0016082biological_processsynaptic vesicle priming
F0016234cellular_componentinclusion body
F0016491molecular_functionoxidoreductase activity
F0019894molecular_functionkinesin binding
F0019899molecular_functionenzyme binding
F0019904molecular_functionprotein domain specific binding
F0030424cellular_componentaxon
F0030426cellular_componentgrowth cone
F0030544molecular_functionHsp70 protein binding
F0030659cellular_componentcytoplasmic vesicle membrane
F0030672cellular_componentsynaptic vesicle membrane
F0031092cellular_componentplatelet alpha granule membrane
F0031115biological_processnegative regulation of microtubule polymerization
F0031623biological_processreceptor internalization
F0031648biological_processprotein destabilization
F0032026biological_processresponse to magnesium ion
F0032496biological_processresponse to lipopolysaccharide
F0032991cellular_componentprotein-containing complex
F0034341biological_processresponse to type II interferon
F0034599biological_processcellular response to oxidative stress
F0035493biological_processSNARE complex assembly
F0035543biological_processpositive regulation of SNARE complex assembly
F0040012biological_processregulation of locomotion
F0042220biological_processresponse to cocaine
F0042393molecular_functionhistone binding
F0042416biological_processdopamine biosynthetic process
F0042417biological_processdopamine metabolic process
F0042775biological_processmitochondrial ATP synthesis coupled electron transport
F0042802molecular_functionidentical protein binding
F0042995cellular_componentcell projection
F0043014molecular_functionalpha-tubulin binding
F0043025cellular_componentneuronal cell body
F0043030biological_processregulation of macrophage activation
F0043065biological_processpositive regulation of apoptotic process
F0043066biological_processnegative regulation of apoptotic process
F0043195cellular_componentterminal bouton
F0043274molecular_functionphospholipase binding
F0043524biological_processnegative regulation of neuron apoptotic process
F0043679cellular_componentaxon terminus
F0044344biological_processcellular response to fibroblast growth factor stimulus
F0045202cellular_componentsynapse
F0045807biological_processpositive regulation of endocytosis
F0045920biological_processnegative regulation of exocytosis
F0045921biological_processpositive regulation of exocytosis
F0045963biological_processnegative regulation of dopamine metabolic process
F0046872molecular_functionmetal ion binding
F0046928biological_processregulation of neurotransmitter secretion
F0048148biological_processbehavioral response to cocaine
F0048156molecular_functiontau protein binding
F0048168biological_processregulation of neuronal synaptic plasticity
F0048169biological_processregulation of long-term neuronal synaptic plasticity
F0048471cellular_componentperinuclear region of cytoplasm
F0048487molecular_functionbeta-tubulin binding
F0048488biological_processsynaptic vesicle endocytosis
F0048489biological_processsynaptic vesicle transport
F0050729biological_processpositive regulation of inflammatory response
F0050806biological_processpositive regulation of synaptic transmission
F0050808biological_processsynapse organization
F0050812biological_processregulation of acyl-CoA biosynthetic process
F0051219molecular_functionphosphoprotein binding
F0051259biological_processprotein complex oligomerization
F0051262biological_processprotein tetramerization
F0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
F0051402biological_processneuron apoptotic process
F0051583biological_processdopamine uptake involved in synaptic transmission
F0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
F0051612biological_processnegative regulation of serotonin uptake
F0051621biological_processregulation of norepinephrine uptake
F0051622biological_processnegative regulation of norepinephrine uptake
F0055074biological_processcalcium ion homeostasis
F0060079biological_processexcitatory postsynaptic potential
F0060090molecular_functionmolecular adaptor activity
F0060291biological_processlong-term synaptic potentiation
F0060732biological_processpositive regulation of inositol phosphate biosynthetic process
F0060961molecular_functionphospholipase D inhibitor activity
F0061024biological_processmembrane organization
F0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
F0070507biological_processregulation of microtubule cytoskeleton organization
F0070555biological_processresponse to interleukin-1
F0070840molecular_functiondynein complex binding
F0071280biological_processcellular response to copper ion
F0071872biological_processcellular response to epinephrine stimulus
F0097435biological_processsupramolecular fiber organization
F0098793cellular_componentpresynapse
F0098794cellular_componentpostsynapse
F0099512cellular_componentsupramolecular fiber
F0140311molecular_functionprotein sequestering activity
F0141108molecular_functiontransporter regulator activity
F1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
F1903136molecular_functioncuprous ion binding
F1903285biological_processpositive regulation of hydrogen peroxide catabolic process
F1903421biological_processregulation of synaptic vesicle recycling
F1903426biological_processregulation of reactive oxygen species biosynthetic process
F1904307biological_processresponse to desipramine
F1904377biological_processpositive regulation of protein localization to cell periphery
F1904715biological_processnegative regulation of chaperone-mediated autophagy
F1905606biological_processregulation of presynapse assembly
F1990000biological_processamyloid fibril formation
F2000377biological_processregulation of reactive oxygen species metabolic process
G0000122biological_processnegative regulation of transcription by RNA polymerase II
G0000149molecular_functionSNARE binding
G0000287molecular_functionmagnesium ion binding
G0000976molecular_functiontranscription cis-regulatory region binding
G0001774biological_processmicroglial cell activation
G0001921biological_processpositive regulation of receptor recycling
G0001956biological_processpositive regulation of neurotransmitter secretion
G0001963biological_processsynaptic transmission, dopaminergic
G0003779molecular_functionactin binding
G0004857molecular_functionenzyme inhibitor activity
G0004860molecular_functionprotein kinase inhibitor activity
G0004869molecular_functioncysteine-type endopeptidase inhibitor activity
G0005504molecular_functionfatty acid binding
G0005507molecular_functioncopper ion binding
G0005509molecular_functioncalcium ion binding
G0005515molecular_functionprotein binding
G0005543molecular_functionphospholipid binding
G0005576cellular_componentextracellular region
G0005615cellular_componentextracellular space
G0005634cellular_componentnucleus
G0005640cellular_componentnuclear outer membrane
G0005737cellular_componentcytoplasm
G0005739cellular_componentmitochondrion
G0005741cellular_componentmitochondrial outer membrane
G0005743cellular_componentmitochondrial inner membrane
G0005759cellular_componentmitochondrial matrix
G0005764cellular_componentlysosome
G0005829cellular_componentcytosol
G0005840cellular_componentribosome
G0005856cellular_componentcytoskeleton
G0005886cellular_componentplasma membrane
G0005938cellular_componentcell cortex
G0006631biological_processfatty acid metabolic process
G0006638biological_processneutral lipid metabolic process
G0006644biological_processphospholipid metabolic process
G0006749biological_processglutathione metabolic process
G0007006biological_processmitochondrial membrane organization
G0007268biological_processchemical synaptic transmission
G0007269biological_processneurotransmitter secretion
G0008017molecular_functionmicrotubule binding
G0008021cellular_componentsynaptic vesicle
G0008047molecular_functionenzyme activator activity
G0008198molecular_functionferrous iron binding
G0008270molecular_functionzinc ion binding
G0008289molecular_functionlipid binding
G0008344biological_processadult locomotory behavior
G0009410biological_processresponse to xenobiotic stimulus
G0010040biological_processresponse to iron(II) ion
G0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
G0014048biological_processregulation of glutamate secretion
G0014059biological_processregulation of dopamine secretion
G0015629cellular_componentactin cytoskeleton
G0016020cellular_componentmembrane
G0016079biological_processsynaptic vesicle exocytosis
G0016082biological_processsynaptic vesicle priming
G0016234cellular_componentinclusion body
G0016491molecular_functionoxidoreductase activity
G0019894molecular_functionkinesin binding
G0019899molecular_functionenzyme binding
G0019904molecular_functionprotein domain specific binding
G0030424cellular_componentaxon
G0030426cellular_componentgrowth cone
G0030544molecular_functionHsp70 protein binding
G0030659cellular_componentcytoplasmic vesicle membrane
G0030672cellular_componentsynaptic vesicle membrane
G0031092cellular_componentplatelet alpha granule membrane
G0031115biological_processnegative regulation of microtubule polymerization
G0031623biological_processreceptor internalization
G0031648biological_processprotein destabilization
G0032026biological_processresponse to magnesium ion
G0032496biological_processresponse to lipopolysaccharide
G0032991cellular_componentprotein-containing complex
G0034341biological_processresponse to type II interferon
G0034599biological_processcellular response to oxidative stress
G0035493biological_processSNARE complex assembly
G0035543biological_processpositive regulation of SNARE complex assembly
G0040012biological_processregulation of locomotion
G0042220biological_processresponse to cocaine
G0042393molecular_functionhistone binding
G0042416biological_processdopamine biosynthetic process
G0042417biological_processdopamine metabolic process
G0042775biological_processmitochondrial ATP synthesis coupled electron transport
G0042802molecular_functionidentical protein binding
G0042995cellular_componentcell projection
G0043014molecular_functionalpha-tubulin binding
G0043025cellular_componentneuronal cell body
G0043030biological_processregulation of macrophage activation
G0043065biological_processpositive regulation of apoptotic process
G0043066biological_processnegative regulation of apoptotic process
G0043195cellular_componentterminal bouton
G0043274molecular_functionphospholipase binding
G0043524biological_processnegative regulation of neuron apoptotic process
G0043679cellular_componentaxon terminus
G0044344biological_processcellular response to fibroblast growth factor stimulus
G0045202cellular_componentsynapse
G0045807biological_processpositive regulation of endocytosis
G0045920biological_processnegative regulation of exocytosis
G0045921biological_processpositive regulation of exocytosis
G0045963biological_processnegative regulation of dopamine metabolic process
G0046872molecular_functionmetal ion binding
G0046928biological_processregulation of neurotransmitter secretion
G0048148biological_processbehavioral response to cocaine
G0048156molecular_functiontau protein binding
G0048168biological_processregulation of neuronal synaptic plasticity
G0048169biological_processregulation of long-term neuronal synaptic plasticity
G0048471cellular_componentperinuclear region of cytoplasm
G0048487molecular_functionbeta-tubulin binding
G0048488biological_processsynaptic vesicle endocytosis
G0048489biological_processsynaptic vesicle transport
G0050729biological_processpositive regulation of inflammatory response
G0050806biological_processpositive regulation of synaptic transmission
G0050808biological_processsynapse organization
G0050812biological_processregulation of acyl-CoA biosynthetic process
G0051219molecular_functionphosphoprotein binding
G0051259biological_processprotein complex oligomerization
G0051262biological_processprotein tetramerization
G0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
G0051402biological_processneuron apoptotic process
G0051583biological_processdopamine uptake involved in synaptic transmission
G0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
G0051612biological_processnegative regulation of serotonin uptake
G0051621biological_processregulation of norepinephrine uptake
G0051622biological_processnegative regulation of norepinephrine uptake
G0055074biological_processcalcium ion homeostasis
G0060079biological_processexcitatory postsynaptic potential
G0060090molecular_functionmolecular adaptor activity
G0060291biological_processlong-term synaptic potentiation
G0060732biological_processpositive regulation of inositol phosphate biosynthetic process
G0060961molecular_functionphospholipase D inhibitor activity
G0061024biological_processmembrane organization
G0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
G0070507biological_processregulation of microtubule cytoskeleton organization
G0070555biological_processresponse to interleukin-1
G0070840molecular_functiondynein complex binding
G0071280biological_processcellular response to copper ion
G0071872biological_processcellular response to epinephrine stimulus
G0097435biological_processsupramolecular fiber organization
G0098793cellular_componentpresynapse
G0098794cellular_componentpostsynapse
G0099512cellular_componentsupramolecular fiber
G0140311molecular_functionprotein sequestering activity
G0141108molecular_functiontransporter regulator activity
G1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
G1903136molecular_functioncuprous ion binding
G1903285biological_processpositive regulation of hydrogen peroxide catabolic process
G1903421biological_processregulation of synaptic vesicle recycling
G1903426biological_processregulation of reactive oxygen species biosynthetic process
G1904307biological_processresponse to desipramine
G1904377biological_processpositive regulation of protein localization to cell periphery
G1904715biological_processnegative regulation of chaperone-mediated autophagy
G1905606biological_processregulation of presynapse assembly
G1990000biological_processamyloid fibril formation
G2000377biological_processregulation of reactive oxygen species metabolic process
H0000122biological_processnegative regulation of transcription by RNA polymerase II
H0000149molecular_functionSNARE binding
H0000287molecular_functionmagnesium ion binding
H0000976molecular_functiontranscription cis-regulatory region binding
H0001774biological_processmicroglial cell activation
H0001921biological_processpositive regulation of receptor recycling
H0001956biological_processpositive regulation of neurotransmitter secretion
H0001963biological_processsynaptic transmission, dopaminergic
H0003779molecular_functionactin binding
H0004857molecular_functionenzyme inhibitor activity
H0004860molecular_functionprotein kinase inhibitor activity
H0004869molecular_functioncysteine-type endopeptidase inhibitor activity
H0005504molecular_functionfatty acid binding
H0005507molecular_functioncopper ion binding
H0005509molecular_functioncalcium ion binding
H0005515molecular_functionprotein binding
H0005543molecular_functionphospholipid binding
H0005576cellular_componentextracellular region
H0005615cellular_componentextracellular space
H0005634cellular_componentnucleus
H0005640cellular_componentnuclear outer membrane
H0005737cellular_componentcytoplasm
H0005739cellular_componentmitochondrion
H0005741cellular_componentmitochondrial outer membrane
H0005743cellular_componentmitochondrial inner membrane
H0005759cellular_componentmitochondrial matrix
H0005764cellular_componentlysosome
H0005829cellular_componentcytosol
H0005840cellular_componentribosome
H0005856cellular_componentcytoskeleton
H0005886cellular_componentplasma membrane
H0005938cellular_componentcell cortex
H0006631biological_processfatty acid metabolic process
H0006638biological_processneutral lipid metabolic process
H0006644biological_processphospholipid metabolic process
H0006749biological_processglutathione metabolic process
H0007006biological_processmitochondrial membrane organization
H0007268biological_processchemical synaptic transmission
H0007269biological_processneurotransmitter secretion
H0008017molecular_functionmicrotubule binding
H0008021cellular_componentsynaptic vesicle
H0008047molecular_functionenzyme activator activity
H0008198molecular_functionferrous iron binding
H0008270molecular_functionzinc ion binding
H0008289molecular_functionlipid binding
H0008344biological_processadult locomotory behavior
H0009410biological_processresponse to xenobiotic stimulus
H0010040biological_processresponse to iron(II) ion
H0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
H0014048biological_processregulation of glutamate secretion
H0014059biological_processregulation of dopamine secretion
H0015629cellular_componentactin cytoskeleton
H0016020cellular_componentmembrane
H0016079biological_processsynaptic vesicle exocytosis
H0016082biological_processsynaptic vesicle priming
H0016234cellular_componentinclusion body
H0016491molecular_functionoxidoreductase activity
H0019894molecular_functionkinesin binding
H0019899molecular_functionenzyme binding
H0019904molecular_functionprotein domain specific binding
H0030424cellular_componentaxon
H0030426cellular_componentgrowth cone
H0030544molecular_functionHsp70 protein binding
H0030659cellular_componentcytoplasmic vesicle membrane
H0030672cellular_componentsynaptic vesicle membrane
H0031092cellular_componentplatelet alpha granule membrane
H0031115biological_processnegative regulation of microtubule polymerization
H0031623biological_processreceptor internalization
H0031648biological_processprotein destabilization
H0032026biological_processresponse to magnesium ion
H0032496biological_processresponse to lipopolysaccharide
H0032991cellular_componentprotein-containing complex
H0034341biological_processresponse to type II interferon
H0034599biological_processcellular response to oxidative stress
H0035493biological_processSNARE complex assembly
H0035543biological_processpositive regulation of SNARE complex assembly
H0040012biological_processregulation of locomotion
H0042220biological_processresponse to cocaine
H0042393molecular_functionhistone binding
H0042416biological_processdopamine biosynthetic process
H0042417biological_processdopamine metabolic process
H0042775biological_processmitochondrial ATP synthesis coupled electron transport
H0042802molecular_functionidentical protein binding
H0042995cellular_componentcell projection
H0043014molecular_functionalpha-tubulin binding
H0043025cellular_componentneuronal cell body
H0043030biological_processregulation of macrophage activation
H0043065biological_processpositive regulation of apoptotic process
H0043066biological_processnegative regulation of apoptotic process
H0043195cellular_componentterminal bouton
H0043274molecular_functionphospholipase binding
H0043524biological_processnegative regulation of neuron apoptotic process
H0043679cellular_componentaxon terminus
H0044344biological_processcellular response to fibroblast growth factor stimulus
H0045202cellular_componentsynapse
H0045807biological_processpositive regulation of endocytosis
H0045920biological_processnegative regulation of exocytosis
H0045921biological_processpositive regulation of exocytosis
H0045963biological_processnegative regulation of dopamine metabolic process
H0046872molecular_functionmetal ion binding
H0046928biological_processregulation of neurotransmitter secretion
H0048148biological_processbehavioral response to cocaine
H0048156molecular_functiontau protein binding
H0048168biological_processregulation of neuronal synaptic plasticity
H0048169biological_processregulation of long-term neuronal synaptic plasticity
H0048471cellular_componentperinuclear region of cytoplasm
H0048487molecular_functionbeta-tubulin binding
H0048488biological_processsynaptic vesicle endocytosis
H0048489biological_processsynaptic vesicle transport
H0050729biological_processpositive regulation of inflammatory response
H0050806biological_processpositive regulation of synaptic transmission
H0050808biological_processsynapse organization
H0050812biological_processregulation of acyl-CoA biosynthetic process
H0051219molecular_functionphosphoprotein binding
H0051259biological_processprotein complex oligomerization
H0051262biological_processprotein tetramerization
H0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
H0051402biological_processneuron apoptotic process
H0051583biological_processdopamine uptake involved in synaptic transmission
H0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
H0051612biological_processnegative regulation of serotonin uptake
H0051621biological_processregulation of norepinephrine uptake
H0051622biological_processnegative regulation of norepinephrine uptake
H0055074biological_processcalcium ion homeostasis
H0060079biological_processexcitatory postsynaptic potential
H0060090molecular_functionmolecular adaptor activity
H0060291biological_processlong-term synaptic potentiation
H0060732biological_processpositive regulation of inositol phosphate biosynthetic process
H0060961molecular_functionphospholipase D inhibitor activity
H0061024biological_processmembrane organization
H0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
H0070507biological_processregulation of microtubule cytoskeleton organization
H0070555biological_processresponse to interleukin-1
H0070840molecular_functiondynein complex binding
H0071280biological_processcellular response to copper ion
H0071872biological_processcellular response to epinephrine stimulus
H0097435biological_processsupramolecular fiber organization
H0098793cellular_componentpresynapse
H0098794cellular_componentpostsynapse
H0099512cellular_componentsupramolecular fiber
H0140311molecular_functionprotein sequestering activity
H0141108molecular_functiontransporter regulator activity
H1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
H1903136molecular_functioncuprous ion binding
H1903285biological_processpositive regulation of hydrogen peroxide catabolic process
H1903421biological_processregulation of synaptic vesicle recycling
H1903426biological_processregulation of reactive oxygen species biosynthetic process
H1904307biological_processresponse to desipramine
H1904377biological_processpositive regulation of protein localization to cell periphery
H1904715biological_processnegative regulation of chaperone-mediated autophagy
H1905606biological_processregulation of presynapse assembly
H1990000biological_processamyloid fibril formation
H2000377biological_processregulation of reactive oxygen species metabolic process
I0000122biological_processnegative regulation of transcription by RNA polymerase II
I0000149molecular_functionSNARE binding
I0000287molecular_functionmagnesium ion binding
I0000976molecular_functiontranscription cis-regulatory region binding
I0001774biological_processmicroglial cell activation
I0001921biological_processpositive regulation of receptor recycling
I0001956biological_processpositive regulation of neurotransmitter secretion
I0001963biological_processsynaptic transmission, dopaminergic
I0003779molecular_functionactin binding
I0004857molecular_functionenzyme inhibitor activity
I0004860molecular_functionprotein kinase inhibitor activity
I0004869molecular_functioncysteine-type endopeptidase inhibitor activity
I0005504molecular_functionfatty acid binding
I0005507molecular_functioncopper ion binding
I0005509molecular_functioncalcium ion binding
I0005515molecular_functionprotein binding
I0005543molecular_functionphospholipid binding
I0005576cellular_componentextracellular region
I0005615cellular_componentextracellular space
I0005634cellular_componentnucleus
I0005640cellular_componentnuclear outer membrane
I0005737cellular_componentcytoplasm
I0005739cellular_componentmitochondrion
I0005741cellular_componentmitochondrial outer membrane
I0005743cellular_componentmitochondrial inner membrane
I0005759cellular_componentmitochondrial matrix
I0005764cellular_componentlysosome
I0005829cellular_componentcytosol
I0005840cellular_componentribosome
I0005856cellular_componentcytoskeleton
I0005886cellular_componentplasma membrane
I0005938cellular_componentcell cortex
I0006631biological_processfatty acid metabolic process
I0006638biological_processneutral lipid metabolic process
I0006644biological_processphospholipid metabolic process
I0006749biological_processglutathione metabolic process
I0007006biological_processmitochondrial membrane organization
I0007268biological_processchemical synaptic transmission
I0007269biological_processneurotransmitter secretion
I0008017molecular_functionmicrotubule binding
I0008021cellular_componentsynaptic vesicle
I0008047molecular_functionenzyme activator activity
I0008198molecular_functionferrous iron binding
I0008270molecular_functionzinc ion binding
I0008289molecular_functionlipid binding
I0008344biological_processadult locomotory behavior
I0009410biological_processresponse to xenobiotic stimulus
I0010040biological_processresponse to iron(II) ion
I0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
I0014048biological_processregulation of glutamate secretion
I0014059biological_processregulation of dopamine secretion
I0015629cellular_componentactin cytoskeleton
I0016020cellular_componentmembrane
I0016079biological_processsynaptic vesicle exocytosis
I0016082biological_processsynaptic vesicle priming
I0016234cellular_componentinclusion body
I0016491molecular_functionoxidoreductase activity
I0019894molecular_functionkinesin binding
I0019899molecular_functionenzyme binding
I0019904molecular_functionprotein domain specific binding
I0030424cellular_componentaxon
I0030426cellular_componentgrowth cone
I0030544molecular_functionHsp70 protein binding
I0030659cellular_componentcytoplasmic vesicle membrane
I0030672cellular_componentsynaptic vesicle membrane
I0031092cellular_componentplatelet alpha granule membrane
I0031115biological_processnegative regulation of microtubule polymerization
I0031623biological_processreceptor internalization
I0031648biological_processprotein destabilization
I0032026biological_processresponse to magnesium ion
I0032496biological_processresponse to lipopolysaccharide
I0032991cellular_componentprotein-containing complex
I0034341biological_processresponse to type II interferon
I0034599biological_processcellular response to oxidative stress
I0035493biological_processSNARE complex assembly
I0035543biological_processpositive regulation of SNARE complex assembly
I0040012biological_processregulation of locomotion
I0042220biological_processresponse to cocaine
I0042393molecular_functionhistone binding
I0042416biological_processdopamine biosynthetic process
I0042417biological_processdopamine metabolic process
I0042775biological_processmitochondrial ATP synthesis coupled electron transport
I0042802molecular_functionidentical protein binding
I0042995cellular_componentcell projection
I0043014molecular_functionalpha-tubulin binding
I0043025cellular_componentneuronal cell body
I0043030biological_processregulation of macrophage activation
I0043065biological_processpositive regulation of apoptotic process
I0043066biological_processnegative regulation of apoptotic process
I0043195cellular_componentterminal bouton
I0043274molecular_functionphospholipase binding
I0043524biological_processnegative regulation of neuron apoptotic process
I0043679cellular_componentaxon terminus
I0044344biological_processcellular response to fibroblast growth factor stimulus
I0045202cellular_componentsynapse
I0045807biological_processpositive regulation of endocytosis
I0045920biological_processnegative regulation of exocytosis
I0045921biological_processpositive regulation of exocytosis
I0045963biological_processnegative regulation of dopamine metabolic process
I0046872molecular_functionmetal ion binding
I0046928biological_processregulation of neurotransmitter secretion
I0048148biological_processbehavioral response to cocaine
I0048156molecular_functiontau protein binding
I0048168biological_processregulation of neuronal synaptic plasticity
I0048169biological_processregulation of long-term neuronal synaptic plasticity
I0048471cellular_componentperinuclear region of cytoplasm
I0048487molecular_functionbeta-tubulin binding
I0048488biological_processsynaptic vesicle endocytosis
I0048489biological_processsynaptic vesicle transport
I0050729biological_processpositive regulation of inflammatory response
I0050806biological_processpositive regulation of synaptic transmission
I0050808biological_processsynapse organization
I0050812biological_processregulation of acyl-CoA biosynthetic process
I0051219molecular_functionphosphoprotein binding
I0051259biological_processprotein complex oligomerization
I0051262biological_processprotein tetramerization
I0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
I0051402biological_processneuron apoptotic process
I0051583biological_processdopamine uptake involved in synaptic transmission
I0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
I0051612biological_processnegative regulation of serotonin uptake
I0051621biological_processregulation of norepinephrine uptake
I0051622biological_processnegative regulation of norepinephrine uptake
I0055074biological_processcalcium ion homeostasis
I0060079biological_processexcitatory postsynaptic potential
I0060090molecular_functionmolecular adaptor activity
I0060291biological_processlong-term synaptic potentiation
I0060732biological_processpositive regulation of inositol phosphate biosynthetic process
I0060961molecular_functionphospholipase D inhibitor activity
I0061024biological_processmembrane organization
I0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
I0070507biological_processregulation of microtubule cytoskeleton organization
I0070555biological_processresponse to interleukin-1
I0070840molecular_functiondynein complex binding
I0071280biological_processcellular response to copper ion
I0071872biological_processcellular response to epinephrine stimulus
I0097435biological_processsupramolecular fiber organization
I0098793cellular_componentpresynapse
I0098794cellular_componentpostsynapse
I0099512cellular_componentsupramolecular fiber
I0140311molecular_functionprotein sequestering activity
I0141108molecular_functiontransporter regulator activity
I1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
I1903136molecular_functioncuprous ion binding
I1903285biological_processpositive regulation of hydrogen peroxide catabolic process
I1903421biological_processregulation of synaptic vesicle recycling
I1903426biological_processregulation of reactive oxygen species biosynthetic process
I1904307biological_processresponse to desipramine
I1904377biological_processpositive regulation of protein localization to cell periphery
I1904715biological_processnegative regulation of chaperone-mediated autophagy
I1905606biological_processregulation of presynapse assembly
I1990000biological_processamyloid fibril formation
I2000377biological_processregulation of reactive oxygen species metabolic process
J0000122biological_processnegative regulation of transcription by RNA polymerase II
J0000149molecular_functionSNARE binding
J0000287molecular_functionmagnesium ion binding
J0000976molecular_functiontranscription cis-regulatory region binding
J0001774biological_processmicroglial cell activation
J0001921biological_processpositive regulation of receptor recycling
J0001956biological_processpositive regulation of neurotransmitter secretion
J0001963biological_processsynaptic transmission, dopaminergic
J0003779molecular_functionactin binding
J0004857molecular_functionenzyme inhibitor activity
J0004860molecular_functionprotein kinase inhibitor activity
J0004869molecular_functioncysteine-type endopeptidase inhibitor activity
J0005504molecular_functionfatty acid binding
J0005507molecular_functioncopper ion binding
J0005509molecular_functioncalcium ion binding
J0005515molecular_functionprotein binding
J0005543molecular_functionphospholipid binding
J0005576cellular_componentextracellular region
J0005615cellular_componentextracellular space
J0005634cellular_componentnucleus
J0005640cellular_componentnuclear outer membrane
J0005737cellular_componentcytoplasm
J0005739cellular_componentmitochondrion
J0005741cellular_componentmitochondrial outer membrane
J0005743cellular_componentmitochondrial inner membrane
J0005759cellular_componentmitochondrial matrix
J0005764cellular_componentlysosome
J0005829cellular_componentcytosol
J0005840cellular_componentribosome
J0005856cellular_componentcytoskeleton
J0005886cellular_componentplasma membrane
J0005938cellular_componentcell cortex
J0006631biological_processfatty acid metabolic process
J0006638biological_processneutral lipid metabolic process
J0006644biological_processphospholipid metabolic process
J0006749biological_processglutathione metabolic process
J0007006biological_processmitochondrial membrane organization
J0007268biological_processchemical synaptic transmission
J0007269biological_processneurotransmitter secretion
J0008017molecular_functionmicrotubule binding
J0008021cellular_componentsynaptic vesicle
J0008047molecular_functionenzyme activator activity
J0008198molecular_functionferrous iron binding
J0008270molecular_functionzinc ion binding
J0008289molecular_functionlipid binding
J0008344biological_processadult locomotory behavior
J0009410biological_processresponse to xenobiotic stimulus
J0010040biological_processresponse to iron(II) ion
J0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
J0014048biological_processregulation of glutamate secretion
J0014059biological_processregulation of dopamine secretion
J0015629cellular_componentactin cytoskeleton
J0016020cellular_componentmembrane
J0016079biological_processsynaptic vesicle exocytosis
J0016082biological_processsynaptic vesicle priming
J0016234cellular_componentinclusion body
J0016491molecular_functionoxidoreductase activity
J0019894molecular_functionkinesin binding
J0019899molecular_functionenzyme binding
J0019904molecular_functionprotein domain specific binding
J0030424cellular_componentaxon
J0030426cellular_componentgrowth cone
J0030544molecular_functionHsp70 protein binding
J0030659cellular_componentcytoplasmic vesicle membrane
J0030672cellular_componentsynaptic vesicle membrane
J0031092cellular_componentplatelet alpha granule membrane
J0031115biological_processnegative regulation of microtubule polymerization
J0031623biological_processreceptor internalization
J0031648biological_processprotein destabilization
J0032026biological_processresponse to magnesium ion
J0032496biological_processresponse to lipopolysaccharide
J0032991cellular_componentprotein-containing complex
J0034341biological_processresponse to type II interferon
J0034599biological_processcellular response to oxidative stress
J0035493biological_processSNARE complex assembly
J0035543biological_processpositive regulation of SNARE complex assembly
J0040012biological_processregulation of locomotion
J0042220biological_processresponse to cocaine
J0042393molecular_functionhistone binding
J0042416biological_processdopamine biosynthetic process
J0042417biological_processdopamine metabolic process
J0042775biological_processmitochondrial ATP synthesis coupled electron transport
J0042802molecular_functionidentical protein binding
J0042995cellular_componentcell projection
J0043014molecular_functionalpha-tubulin binding
J0043025cellular_componentneuronal cell body
J0043030biological_processregulation of macrophage activation
J0043065biological_processpositive regulation of apoptotic process
J0043066biological_processnegative regulation of apoptotic process
J0043195cellular_componentterminal bouton
J0043274molecular_functionphospholipase binding
J0043524biological_processnegative regulation of neuron apoptotic process
J0043679cellular_componentaxon terminus
J0044344biological_processcellular response to fibroblast growth factor stimulus
J0045202cellular_componentsynapse
J0045807biological_processpositive regulation of endocytosis
J0045920biological_processnegative regulation of exocytosis
J0045921biological_processpositive regulation of exocytosis
J0045963biological_processnegative regulation of dopamine metabolic process
J0046872molecular_functionmetal ion binding
J0046928biological_processregulation of neurotransmitter secretion
J0048148biological_processbehavioral response to cocaine
J0048156molecular_functiontau protein binding
J0048168biological_processregulation of neuronal synaptic plasticity
J0048169biological_processregulation of long-term neuronal synaptic plasticity
J0048471cellular_componentperinuclear region of cytoplasm
J0048487molecular_functionbeta-tubulin binding
J0048488biological_processsynaptic vesicle endocytosis
J0048489biological_processsynaptic vesicle transport
J0050729biological_processpositive regulation of inflammatory response
J0050806biological_processpositive regulation of synaptic transmission
J0050808biological_processsynapse organization
J0050812biological_processregulation of acyl-CoA biosynthetic process
J0051219molecular_functionphosphoprotein binding
J0051259biological_processprotein complex oligomerization
J0051262biological_processprotein tetramerization
J0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
J0051402biological_processneuron apoptotic process
J0051583biological_processdopamine uptake involved in synaptic transmission
J0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
J0051612biological_processnegative regulation of serotonin uptake
J0051621biological_processregulation of norepinephrine uptake
J0051622biological_processnegative regulation of norepinephrine uptake
J0055074biological_processcalcium ion homeostasis
J0060079biological_processexcitatory postsynaptic potential
J0060090molecular_functionmolecular adaptor activity
J0060291biological_processlong-term synaptic potentiation
J0060732biological_processpositive regulation of inositol phosphate biosynthetic process
J0060961molecular_functionphospholipase D inhibitor activity
J0061024biological_processmembrane organization
J0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
J0070507biological_processregulation of microtubule cytoskeleton organization
J0070555biological_processresponse to interleukin-1
J0070840molecular_functiondynein complex binding
J0071280biological_processcellular response to copper ion
J0071872biological_processcellular response to epinephrine stimulus
J0097435biological_processsupramolecular fiber organization
J0098793cellular_componentpresynapse
J0098794cellular_componentpostsynapse
J0099512cellular_componentsupramolecular fiber
J0140311molecular_functionprotein sequestering activity
J0141108molecular_functiontransporter regulator activity
J1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
J1903136molecular_functioncuprous ion binding
J1903285biological_processpositive regulation of hydrogen peroxide catabolic process
J1903421biological_processregulation of synaptic vesicle recycling
J1903426biological_processregulation of reactive oxygen species biosynthetic process
J1904307biological_processresponse to desipramine
J1904377biological_processpositive regulation of protein localization to cell periphery
J1904715biological_processnegative regulation of chaperone-mediated autophagy
J1905606biological_processregulation of presynapse assembly
J1990000biological_processamyloid fibril formation
J2000377biological_processregulation of reactive oxygen species metabolic process
K0000122biological_processnegative regulation of transcription by RNA polymerase II
K0000149molecular_functionSNARE binding
K0000287molecular_functionmagnesium ion binding
K0000976molecular_functiontranscription cis-regulatory region binding
K0001774biological_processmicroglial cell activation
K0001921biological_processpositive regulation of receptor recycling
K0001956biological_processpositive regulation of neurotransmitter secretion
K0001963biological_processsynaptic transmission, dopaminergic
K0003779molecular_functionactin binding
K0004857molecular_functionenzyme inhibitor activity
K0004860molecular_functionprotein kinase inhibitor activity
K0004869molecular_functioncysteine-type endopeptidase inhibitor activity
K0005504molecular_functionfatty acid binding
K0005507molecular_functioncopper ion binding
K0005509molecular_functioncalcium ion binding
K0005515molecular_functionprotein binding
K0005543molecular_functionphospholipid binding
K0005576cellular_componentextracellular region
K0005615cellular_componentextracellular space
K0005634cellular_componentnucleus
K0005640cellular_componentnuclear outer membrane
K0005737cellular_componentcytoplasm
K0005739cellular_componentmitochondrion
K0005741cellular_componentmitochondrial outer membrane
K0005743cellular_componentmitochondrial inner membrane
K0005759cellular_componentmitochondrial matrix
K0005764cellular_componentlysosome
K0005829cellular_componentcytosol
K0005840cellular_componentribosome
K0005856cellular_componentcytoskeleton
K0005886cellular_componentplasma membrane
K0005938cellular_componentcell cortex
K0006631biological_processfatty acid metabolic process
K0006638biological_processneutral lipid metabolic process
K0006644biological_processphospholipid metabolic process
K0006749biological_processglutathione metabolic process
K0007006biological_processmitochondrial membrane organization
K0007268biological_processchemical synaptic transmission
K0007269biological_processneurotransmitter secretion
K0008017molecular_functionmicrotubule binding
K0008021cellular_componentsynaptic vesicle
K0008047molecular_functionenzyme activator activity
K0008198molecular_functionferrous iron binding
K0008270molecular_functionzinc ion binding
K0008289molecular_functionlipid binding
K0008344biological_processadult locomotory behavior
K0009410biological_processresponse to xenobiotic stimulus
K0010040biological_processresponse to iron(II) ion
K0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
K0014048biological_processregulation of glutamate secretion
K0014059biological_processregulation of dopamine secretion
K0015629cellular_componentactin cytoskeleton
K0016020cellular_componentmembrane
K0016079biological_processsynaptic vesicle exocytosis
K0016082biological_processsynaptic vesicle priming
K0016234cellular_componentinclusion body
K0016491molecular_functionoxidoreductase activity
K0019894molecular_functionkinesin binding
K0019899molecular_functionenzyme binding
K0019904molecular_functionprotein domain specific binding
K0030424cellular_componentaxon
K0030426cellular_componentgrowth cone
K0030544molecular_functionHsp70 protein binding
K0030659cellular_componentcytoplasmic vesicle membrane
K0030672cellular_componentsynaptic vesicle membrane
K0031092cellular_componentplatelet alpha granule membrane
K0031115biological_processnegative regulation of microtubule polymerization
K0031623biological_processreceptor internalization
K0031648biological_processprotein destabilization
K0032026biological_processresponse to magnesium ion
K0032496biological_processresponse to lipopolysaccharide
K0032991cellular_componentprotein-containing complex
K0034341biological_processresponse to type II interferon
K0034599biological_processcellular response to oxidative stress
K0035493biological_processSNARE complex assembly
K0035543biological_processpositive regulation of SNARE complex assembly
K0040012biological_processregulation of locomotion
K0042220biological_processresponse to cocaine
K0042393molecular_functionhistone binding
K0042416biological_processdopamine biosynthetic process
K0042417biological_processdopamine metabolic process
K0042775biological_processmitochondrial ATP synthesis coupled electron transport
K0042802molecular_functionidentical protein binding
K0042995cellular_componentcell projection
K0043014molecular_functionalpha-tubulin binding
K0043025cellular_componentneuronal cell body
K0043030biological_processregulation of macrophage activation
K0043065biological_processpositive regulation of apoptotic process
K0043066biological_processnegative regulation of apoptotic process
K0043195cellular_componentterminal bouton
K0043274molecular_functionphospholipase binding
K0043524biological_processnegative regulation of neuron apoptotic process
K0043679cellular_componentaxon terminus
K0044344biological_processcellular response to fibroblast growth factor stimulus
K0045202cellular_componentsynapse
K0045807biological_processpositive regulation of endocytosis
K0045920biological_processnegative regulation of exocytosis
K0045921biological_processpositive regulation of exocytosis
K0045963biological_processnegative regulation of dopamine metabolic process
K0046872molecular_functionmetal ion binding
K0046928biological_processregulation of neurotransmitter secretion
K0048148biological_processbehavioral response to cocaine
K0048156molecular_functiontau protein binding
K0048168biological_processregulation of neuronal synaptic plasticity
K0048169biological_processregulation of long-term neuronal synaptic plasticity
K0048471cellular_componentperinuclear region of cytoplasm
K0048487molecular_functionbeta-tubulin binding
K0048488biological_processsynaptic vesicle endocytosis
K0048489biological_processsynaptic vesicle transport
K0050729biological_processpositive regulation of inflammatory response
K0050806biological_processpositive regulation of synaptic transmission
K0050808biological_processsynapse organization
K0050812biological_processregulation of acyl-CoA biosynthetic process
K0051219molecular_functionphosphoprotein binding
K0051259biological_processprotein complex oligomerization
K0051262biological_processprotein tetramerization
K0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
K0051402biological_processneuron apoptotic process
K0051583biological_processdopamine uptake involved in synaptic transmission
K0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
K0051612biological_processnegative regulation of serotonin uptake
K0051621biological_processregulation of norepinephrine uptake
K0051622biological_processnegative regulation of norepinephrine uptake
K0055074biological_processcalcium ion homeostasis
K0060079biological_processexcitatory postsynaptic potential
K0060090molecular_functionmolecular adaptor activity
K0060291biological_processlong-term synaptic potentiation
K0060732biological_processpositive regulation of inositol phosphate biosynthetic process
K0060961molecular_functionphospholipase D inhibitor activity
K0061024biological_processmembrane organization
K0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
K0070507biological_processregulation of microtubule cytoskeleton organization
K0070555biological_processresponse to interleukin-1
K0070840molecular_functiondynein complex binding
K0071280biological_processcellular response to copper ion
K0071872biological_processcellular response to epinephrine stimulus
K0097435biological_processsupramolecular fiber organization
K0098793cellular_componentpresynapse
K0098794cellular_componentpostsynapse
K0099512cellular_componentsupramolecular fiber
K0140311molecular_functionprotein sequestering activity
K0141108molecular_functiontransporter regulator activity
K1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
K1903136molecular_functioncuprous ion binding
K1903285biological_processpositive regulation of hydrogen peroxide catabolic process
K1903421biological_processregulation of synaptic vesicle recycling
K1903426biological_processregulation of reactive oxygen species biosynthetic process
K1904307biological_processresponse to desipramine
K1904377biological_processpositive regulation of protein localization to cell periphery
K1904715biological_processnegative regulation of chaperone-mediated autophagy
K1905606biological_processregulation of presynapse assembly
K1990000biological_processamyloid fibril formation
K2000377biological_processregulation of reactive oxygen species metabolic process
L0000122biological_processnegative regulation of transcription by RNA polymerase II
L0000149molecular_functionSNARE binding
L0000287molecular_functionmagnesium ion binding
L0000976molecular_functiontranscription cis-regulatory region binding
L0001774biological_processmicroglial cell activation
L0001921biological_processpositive regulation of receptor recycling
L0001956biological_processpositive regulation of neurotransmitter secretion
L0001963biological_processsynaptic transmission, dopaminergic
L0003779molecular_functionactin binding
L0004857molecular_functionenzyme inhibitor activity
L0004860molecular_functionprotein kinase inhibitor activity
L0004869molecular_functioncysteine-type endopeptidase inhibitor activity
L0005504molecular_functionfatty acid binding
L0005507molecular_functioncopper ion binding
L0005509molecular_functioncalcium ion binding
L0005515molecular_functionprotein binding
L0005543molecular_functionphospholipid binding
L0005576cellular_componentextracellular region
L0005615cellular_componentextracellular space
L0005634cellular_componentnucleus
L0005640cellular_componentnuclear outer membrane
L0005737cellular_componentcytoplasm
L0005739cellular_componentmitochondrion
L0005741cellular_componentmitochondrial outer membrane
L0005743cellular_componentmitochondrial inner membrane
L0005759cellular_componentmitochondrial matrix
L0005764cellular_componentlysosome
L0005829cellular_componentcytosol
L0005840cellular_componentribosome
L0005856cellular_componentcytoskeleton
L0005886cellular_componentplasma membrane
L0005938cellular_componentcell cortex
L0006631biological_processfatty acid metabolic process
L0006638biological_processneutral lipid metabolic process
L0006644biological_processphospholipid metabolic process
L0006749biological_processglutathione metabolic process
L0007006biological_processmitochondrial membrane organization
L0007268biological_processchemical synaptic transmission
L0007269biological_processneurotransmitter secretion
L0008017molecular_functionmicrotubule binding
L0008021cellular_componentsynaptic vesicle
L0008047molecular_functionenzyme activator activity
L0008198molecular_functionferrous iron binding
L0008270molecular_functionzinc ion binding
L0008289molecular_functionlipid binding
L0008344biological_processadult locomotory behavior
L0009410biological_processresponse to xenobiotic stimulus
L0010040biological_processresponse to iron(II) ion
L0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
L0014048biological_processregulation of glutamate secretion
L0014059biological_processregulation of dopamine secretion
L0015629cellular_componentactin cytoskeleton
L0016020cellular_componentmembrane
L0016079biological_processsynaptic vesicle exocytosis
L0016082biological_processsynaptic vesicle priming
L0016234cellular_componentinclusion body
L0016491molecular_functionoxidoreductase activity
L0019894molecular_functionkinesin binding
L0019899molecular_functionenzyme binding
L0019904molecular_functionprotein domain specific binding
L0030424cellular_componentaxon
L0030426cellular_componentgrowth cone
L0030544molecular_functionHsp70 protein binding
L0030659cellular_componentcytoplasmic vesicle membrane
L0030672cellular_componentsynaptic vesicle membrane
L0031092cellular_componentplatelet alpha granule membrane
L0031115biological_processnegative regulation of microtubule polymerization
L0031623biological_processreceptor internalization
L0031648biological_processprotein destabilization
L0032026biological_processresponse to magnesium ion
L0032496biological_processresponse to lipopolysaccharide
L0032991cellular_componentprotein-containing complex
L0034341biological_processresponse to type II interferon
L0034599biological_processcellular response to oxidative stress
L0035493biological_processSNARE complex assembly
L0035543biological_processpositive regulation of SNARE complex assembly
L0040012biological_processregulation of locomotion
L0042220biological_processresponse to cocaine
L0042393molecular_functionhistone binding
L0042416biological_processdopamine biosynthetic process
L0042417biological_processdopamine metabolic process
L0042775biological_processmitochondrial ATP synthesis coupled electron transport
L0042802molecular_functionidentical protein binding
L0042995cellular_componentcell projection
L0043014molecular_functionalpha-tubulin binding
L0043025cellular_componentneuronal cell body
L0043030biological_processregulation of macrophage activation
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Q0043679cellular_componentaxon terminus
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Q0051262biological_processprotein tetramerization
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Q0051612biological_processnegative regulation of serotonin uptake
Q0051621biological_processregulation of norepinephrine uptake
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R0005615cellular_componentextracellular space
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R0005737cellular_componentcytoplasm
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R0005759cellular_componentmitochondrial matrix
R0005764cellular_componentlysosome
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R0007268biological_processchemical synaptic transmission
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R0014059biological_processregulation of dopamine secretion
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R0016234cellular_componentinclusion body
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R0019904molecular_functionprotein domain specific binding
R0030424cellular_componentaxon
R0030426cellular_componentgrowth cone
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R0030659cellular_componentcytoplasmic vesicle membrane
R0030672cellular_componentsynaptic vesicle membrane
R0031092cellular_componentplatelet alpha granule membrane
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R0031623biological_processreceptor internalization
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R0032026biological_processresponse to magnesium ion
R0032496biological_processresponse to lipopolysaccharide
R0032991cellular_componentprotein-containing complex
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R0034599biological_processcellular response to oxidative stress
R0035493biological_processSNARE complex assembly
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R0040012biological_processregulation of locomotion
R0042220biological_processresponse to cocaine
R0042393molecular_functionhistone binding
R0042416biological_processdopamine biosynthetic process
R0042417biological_processdopamine metabolic process
R0042775biological_processmitochondrial ATP synthesis coupled electron transport
R0042802molecular_functionidentical protein binding
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R0043025cellular_componentneuronal cell body
R0043030biological_processregulation of macrophage activation
R0043065biological_processpositive regulation of apoptotic process
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R0043195cellular_componentterminal bouton
R0043274molecular_functionphospholipase binding
R0043524biological_processnegative regulation of neuron apoptotic process
R0043679cellular_componentaxon terminus
R0044344biological_processcellular response to fibroblast growth factor stimulus
R0045202cellular_componentsynapse
R0045807biological_processpositive regulation of endocytosis
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R0045921biological_processpositive regulation of exocytosis
R0045963biological_processnegative regulation of dopamine metabolic process
R0046872molecular_functionmetal ion binding
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R0048148biological_processbehavioral response to cocaine
R0048156molecular_functiontau protein binding
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R0048471cellular_componentperinuclear region of cytoplasm
R0048487molecular_functionbeta-tubulin binding
R0048488biological_processsynaptic vesicle endocytosis
R0048489biological_processsynaptic vesicle transport
R0050729biological_processpositive regulation of inflammatory response
R0050806biological_processpositive regulation of synaptic transmission
R0050808biological_processsynapse organization
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R0051219molecular_functionphosphoprotein binding
R0051259biological_processprotein complex oligomerization
R0051262biological_processprotein tetramerization
R0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
R0051402biological_processneuron apoptotic process
R0051583biological_processdopamine uptake involved in synaptic transmission
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R0051612biological_processnegative regulation of serotonin uptake
R0051621biological_processregulation of norepinephrine uptake
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R0055074biological_processcalcium ion homeostasis
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R0060291biological_processlong-term synaptic potentiation
R0060732biological_processpositive regulation of inositol phosphate biosynthetic process
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R0061024biological_processmembrane organization
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R0070555biological_processresponse to interleukin-1
R0070840molecular_functiondynein complex binding
R0071280biological_processcellular response to copper ion
R0071872biological_processcellular response to epinephrine stimulus
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R0098793cellular_componentpresynapse
R0098794cellular_componentpostsynapse
R0099512cellular_componentsupramolecular fiber
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R1903426biological_processregulation of reactive oxygen species biosynthetic process
R1904307biological_processresponse to desipramine
R1904377biological_processpositive regulation of protein localization to cell periphery
R1904715biological_processnegative regulation of chaperone-mediated autophagy
R1905606biological_processregulation of presynapse assembly
R1990000biological_processamyloid fibril formation
R2000377biological_processregulation of reactive oxygen species metabolic process
S0000122biological_processnegative regulation of transcription by RNA polymerase II
S0000149molecular_functionSNARE binding
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S0001774biological_processmicroglial cell activation
S0001921biological_processpositive regulation of receptor recycling
S0001956biological_processpositive regulation of neurotransmitter secretion
S0001963biological_processsynaptic transmission, dopaminergic
S0003779molecular_functionactin binding
S0004857molecular_functionenzyme inhibitor activity
S0004860molecular_functionprotein kinase inhibitor activity
S0004869molecular_functioncysteine-type endopeptidase inhibitor activity
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S0005507molecular_functioncopper ion binding
S0005509molecular_functioncalcium ion binding
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S0005543molecular_functionphospholipid binding
S0005576cellular_componentextracellular region
S0005615cellular_componentextracellular space
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S0005759cellular_componentmitochondrial matrix
S0005764cellular_componentlysosome
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S0005840cellular_componentribosome
S0005856cellular_componentcytoskeleton
S0005886cellular_componentplasma membrane
S0005938cellular_componentcell cortex
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S0006638biological_processneutral lipid metabolic process
S0006644biological_processphospholipid metabolic process
S0006749biological_processglutathione metabolic process
S0007006biological_processmitochondrial membrane organization
S0007268biological_processchemical synaptic transmission
S0007269biological_processneurotransmitter secretion
S0008017molecular_functionmicrotubule binding
S0008021cellular_componentsynaptic vesicle
S0008047molecular_functionenzyme activator activity
S0008198molecular_functionferrous iron binding
S0008270molecular_functionzinc ion binding
S0008289molecular_functionlipid binding
S0008344biological_processadult locomotory behavior
S0009410biological_processresponse to xenobiotic stimulus
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S0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
S0014048biological_processregulation of glutamate secretion
S0014059biological_processregulation of dopamine secretion
S0015629cellular_componentactin cytoskeleton
S0016020cellular_componentmembrane
S0016079biological_processsynaptic vesicle exocytosis
S0016082biological_processsynaptic vesicle priming
S0016234cellular_componentinclusion body
S0016491molecular_functionoxidoreductase activity
S0019894molecular_functionkinesin binding
S0019899molecular_functionenzyme binding
S0019904molecular_functionprotein domain specific binding
S0030424cellular_componentaxon
S0030426cellular_componentgrowth cone
S0030544molecular_functionHsp70 protein binding
S0030659cellular_componentcytoplasmic vesicle membrane
S0030672cellular_componentsynaptic vesicle membrane
S0031092cellular_componentplatelet alpha granule membrane
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S0031623biological_processreceptor internalization
S0031648biological_processprotein destabilization
S0032026biological_processresponse to magnesium ion
S0032496biological_processresponse to lipopolysaccharide
S0032991cellular_componentprotein-containing complex
S0034341biological_processresponse to type II interferon
S0034599biological_processcellular response to oxidative stress
S0035493biological_processSNARE complex assembly
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S0040012biological_processregulation of locomotion
S0042220biological_processresponse to cocaine
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S0042416biological_processdopamine biosynthetic process
S0042417biological_processdopamine metabolic process
S0042775biological_processmitochondrial ATP synthesis coupled electron transport
S0042802molecular_functionidentical protein binding
S0042995cellular_componentcell projection
S0043014molecular_functionalpha-tubulin binding
S0043025cellular_componentneuronal cell body
S0043030biological_processregulation of macrophage activation
S0043065biological_processpositive regulation of apoptotic process
S0043066biological_processnegative regulation of apoptotic process
S0043195cellular_componentterminal bouton
S0043274molecular_functionphospholipase binding
S0043524biological_processnegative regulation of neuron apoptotic process
S0043679cellular_componentaxon terminus
S0044344biological_processcellular response to fibroblast growth factor stimulus
S0045202cellular_componentsynapse
S0045807biological_processpositive regulation of endocytosis
S0045920biological_processnegative regulation of exocytosis
S0045921biological_processpositive regulation of exocytosis
S0045963biological_processnegative regulation of dopamine metabolic process
S0046872molecular_functionmetal ion binding
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S0048148biological_processbehavioral response to cocaine
S0048156molecular_functiontau protein binding
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S0048471cellular_componentperinuclear region of cytoplasm
S0048487molecular_functionbeta-tubulin binding
S0048488biological_processsynaptic vesicle endocytosis
S0048489biological_processsynaptic vesicle transport
S0050729biological_processpositive regulation of inflammatory response
S0050806biological_processpositive regulation of synaptic transmission
S0050808biological_processsynapse organization
S0050812biological_processregulation of acyl-CoA biosynthetic process
S0051219molecular_functionphosphoprotein binding
S0051259biological_processprotein complex oligomerization
S0051262biological_processprotein tetramerization
S0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
S0051402biological_processneuron apoptotic process
S0051583biological_processdopamine uptake involved in synaptic transmission
S0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
S0051612biological_processnegative regulation of serotonin uptake
S0051621biological_processregulation of norepinephrine uptake
S0051622biological_processnegative regulation of norepinephrine uptake
S0055074biological_processcalcium ion homeostasis
S0060079biological_processexcitatory postsynaptic potential
S0060090molecular_functionmolecular adaptor activity
S0060291biological_processlong-term synaptic potentiation
S0060732biological_processpositive regulation of inositol phosphate biosynthetic process
S0060961molecular_functionphospholipase D inhibitor activity
S0061024biological_processmembrane organization
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S0070507biological_processregulation of microtubule cytoskeleton organization
S0070555biological_processresponse to interleukin-1
S0070840molecular_functiondynein complex binding
S0071280biological_processcellular response to copper ion
S0071872biological_processcellular response to epinephrine stimulus
S0097435biological_processsupramolecular fiber organization
S0098793cellular_componentpresynapse
S0098794cellular_componentpostsynapse
S0099512cellular_componentsupramolecular fiber
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S0141108molecular_functiontransporter regulator activity
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S1903426biological_processregulation of reactive oxygen species biosynthetic process
S1904307biological_processresponse to desipramine
S1904377biological_processpositive regulation of protein localization to cell periphery
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S1905606biological_processregulation of presynapse assembly
S1990000biological_processamyloid fibril formation
S2000377biological_processregulation of reactive oxygen species metabolic process
T0000122biological_processnegative regulation of transcription by RNA polymerase II
T0000149molecular_functionSNARE binding
T0000287molecular_functionmagnesium ion binding
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T0001956biological_processpositive regulation of neurotransmitter secretion
T0001963biological_processsynaptic transmission, dopaminergic
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T0004860molecular_functionprotein kinase inhibitor activity
T0004869molecular_functioncysteine-type endopeptidase inhibitor activity
T0005504molecular_functionfatty acid binding
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T0005509molecular_functioncalcium ion binding
T0005515molecular_functionprotein binding
T0005543molecular_functionphospholipid binding
T0005576cellular_componentextracellular region
T0005615cellular_componentextracellular space
T0005634cellular_componentnucleus
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X0000122biological_processnegative regulation of transcription by RNA polymerase II
X0000149molecular_functionSNARE binding
X0000287molecular_functionmagnesium ion binding
X0000976molecular_functiontranscription cis-regulatory region binding
X0001774biological_processmicroglial cell activation
X0001921biological_processpositive regulation of receptor recycling
X0001956biological_processpositive regulation of neurotransmitter secretion
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X0003779molecular_functionactin binding
X0004857molecular_functionenzyme inhibitor activity
X0004860molecular_functionprotein kinase inhibitor activity
X0004869molecular_functioncysteine-type endopeptidase inhibitor activity
X0005504molecular_functionfatty acid binding
X0005507molecular_functioncopper ion binding
X0005509molecular_functioncalcium ion binding
X0005515molecular_functionprotein binding
X0005543molecular_functionphospholipid binding
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X0005615cellular_componentextracellular space
X0005634cellular_componentnucleus
X0005640cellular_componentnuclear outer membrane
X0005737cellular_componentcytoplasm
X0005739cellular_componentmitochondrion
X0005741cellular_componentmitochondrial outer membrane
X0005743cellular_componentmitochondrial inner membrane
X0005759cellular_componentmitochondrial matrix
X0005764cellular_componentlysosome
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X0005840cellular_componentribosome
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X0005886cellular_componentplasma membrane
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X0006638biological_processneutral lipid metabolic process
X0006644biological_processphospholipid metabolic process
X0006749biological_processglutathione metabolic process
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X0007268biological_processchemical synaptic transmission
X0007269biological_processneurotransmitter secretion
X0008017molecular_functionmicrotubule binding
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X0008270molecular_functionzinc ion binding
X0008289molecular_functionlipid binding
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X0010040biological_processresponse to iron(II) ion
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X0030426cellular_componentgrowth cone
X0030544molecular_functionHsp70 protein binding
X0030659cellular_componentcytoplasmic vesicle membrane
X0030672cellular_componentsynaptic vesicle membrane
X0031092cellular_componentplatelet alpha granule membrane
X0031115biological_processnegative regulation of microtubule polymerization
X0031623biological_processreceptor internalization
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X0042393molecular_functionhistone binding
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X0043030biological_processregulation of macrophage activation
X0043065biological_processpositive regulation of apoptotic process
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X0043195cellular_componentterminal bouton
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X0043679cellular_componentaxon terminus
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X0045202cellular_componentsynapse
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X0048156molecular_functiontau protein binding
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X0051612biological_processnegative regulation of serotonin uptake
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X0098793cellular_componentpresynapse
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X0099512cellular_componentsupramolecular fiber
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Y0000122biological_processnegative regulation of transcription by RNA polymerase II
Y0000149molecular_functionSNARE binding
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Y0000976molecular_functiontranscription cis-regulatory region binding
Y0001774biological_processmicroglial cell activation
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Y0004857molecular_functionenzyme inhibitor activity
Y0004860molecular_functionprotein kinase inhibitor activity
Y0004869molecular_functioncysteine-type endopeptidase inhibitor activity
Y0005504molecular_functionfatty acid binding
Y0005507molecular_functioncopper ion binding
Y0005509molecular_functioncalcium ion binding
Y0005515molecular_functionprotein binding
Y0005543molecular_functionphospholipid binding
Y0005576cellular_componentextracellular region
Y0005615cellular_componentextracellular space
Y0005634cellular_componentnucleus
Y0005640cellular_componentnuclear outer membrane
Y0005737cellular_componentcytoplasm
Y0005739cellular_componentmitochondrion
Y0005741cellular_componentmitochondrial outer membrane
Y0005743cellular_componentmitochondrial inner membrane
Y0005759cellular_componentmitochondrial matrix
Y0005764cellular_componentlysosome
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Y0007268biological_processchemical synaptic transmission
Y0007269biological_processneurotransmitter secretion
Y0008017molecular_functionmicrotubule binding
Y0008021cellular_componentsynaptic vesicle
Y0008047molecular_functionenzyme activator activity
Y0008198molecular_functionferrous iron binding
Y0008270molecular_functionzinc ion binding
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Y0030426cellular_componentgrowth cone
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Y0031623biological_processreceptor internalization
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Y0032496biological_processresponse to lipopolysaccharide
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Y0042220biological_processresponse to cocaine
Y0042393molecular_functionhistone binding
Y0042416biological_processdopamine biosynthetic process
Y0042417biological_processdopamine metabolic process
Y0042775biological_processmitochondrial ATP synthesis coupled electron transport
Y0042802molecular_functionidentical protein binding
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Y0043014molecular_functionalpha-tubulin binding
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Y0043195cellular_componentterminal bouton
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Y0043679cellular_componentaxon terminus
Y0044344biological_processcellular response to fibroblast growth factor stimulus
Y0045202cellular_componentsynapse
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Y0045921biological_processpositive regulation of exocytosis
Y0045963biological_processnegative regulation of dopamine metabolic process
Y0046872molecular_functionmetal ion binding
Y0046928biological_processregulation of neurotransmitter secretion
Y0048148biological_processbehavioral response to cocaine
Y0048156molecular_functiontau protein binding
Y0048168biological_processregulation of neuronal synaptic plasticity
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Y0048471cellular_componentperinuclear region of cytoplasm
Y0048487molecular_functionbeta-tubulin binding
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Y0051219molecular_functionphosphoprotein binding
Y0051259biological_processprotein complex oligomerization
Y0051262biological_processprotein tetramerization
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Y0051402biological_processneuron apoptotic process
Y0051583biological_processdopamine uptake involved in synaptic transmission
Y0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
Y0051612biological_processnegative regulation of serotonin uptake
Y0051621biological_processregulation of norepinephrine uptake
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Y0070555biological_processresponse to interleukin-1
Y0070840molecular_functiondynein complex binding
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Z0000122biological_processnegative regulation of transcription by RNA polymerase II
Z0000149molecular_functionSNARE binding
Z0000287molecular_functionmagnesium ion binding
Z0000976molecular_functiontranscription cis-regulatory region binding
Z0001774biological_processmicroglial cell activation
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Z0001956biological_processpositive regulation of neurotransmitter secretion
Z0001963biological_processsynaptic transmission, dopaminergic
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Z0004857molecular_functionenzyme inhibitor activity
Z0004860molecular_functionprotein kinase inhibitor activity
Z0004869molecular_functioncysteine-type endopeptidase inhibitor activity
Z0005504molecular_functionfatty acid binding
Z0005507molecular_functioncopper ion binding
Z0005509molecular_functioncalcium ion binding
Z0005515molecular_functionprotein binding
Z0005543molecular_functionphospholipid binding
Z0005576cellular_componentextracellular region
Z0005615cellular_componentextracellular space
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Z0005640cellular_componentnuclear outer membrane
Z0005737cellular_componentcytoplasm
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Z0005759cellular_componentmitochondrial matrix
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Z0005840cellular_componentribosome
Z0005856cellular_componentcytoskeleton
Z0005886cellular_componentplasma membrane
Z0005938cellular_componentcell cortex
Z0006631biological_processfatty acid metabolic process
Z0006638biological_processneutral lipid metabolic process
Z0006644biological_processphospholipid metabolic process
Z0006749biological_processglutathione metabolic process
Z0007006biological_processmitochondrial membrane organization
Z0007268biological_processchemical synaptic transmission
Z0007269biological_processneurotransmitter secretion
Z0008017molecular_functionmicrotubule binding
Z0008021cellular_componentsynaptic vesicle
Z0008047molecular_functionenzyme activator activity
Z0008198molecular_functionferrous iron binding
Z0008270molecular_functionzinc ion binding
Z0008289molecular_functionlipid binding
Z0008344biological_processadult locomotory behavior
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Z0014059biological_processregulation of dopamine secretion
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Z0016020cellular_componentmembrane
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Z0016234cellular_componentinclusion body
Z0016491molecular_functionoxidoreductase activity
Z0019894molecular_functionkinesin binding
Z0019899molecular_functionenzyme binding
Z0019904molecular_functionprotein domain specific binding
Z0030424cellular_componentaxon
Z0030426cellular_componentgrowth cone
Z0030544molecular_functionHsp70 protein binding
Z0030659cellular_componentcytoplasmic vesicle membrane
Z0030672cellular_componentsynaptic vesicle membrane
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Z0031115biological_processnegative regulation of microtubule polymerization
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Z0032496biological_processresponse to lipopolysaccharide
Z0032991cellular_componentprotein-containing complex
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Z0042416biological_processdopamine biosynthetic process
Z0042417biological_processdopamine metabolic process
Z0042775biological_processmitochondrial ATP synthesis coupled electron transport
Z0042802molecular_functionidentical protein binding
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Z0043014molecular_functionalpha-tubulin binding
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Z0043066biological_processnegative regulation of apoptotic process
Z0043195cellular_componentterminal bouton
Z0043274molecular_functionphospholipase binding
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Z0043679cellular_componentaxon terminus
Z0044344biological_processcellular response to fibroblast growth factor stimulus
Z0045202cellular_componentsynapse
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Z0045920biological_processnegative regulation of exocytosis
Z0045921biological_processpositive regulation of exocytosis
Z0045963biological_processnegative regulation of dopamine metabolic process
Z0046872molecular_functionmetal ion binding
Z0046928biological_processregulation of neurotransmitter secretion
Z0048148biological_processbehavioral response to cocaine
Z0048156molecular_functiontau protein binding
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Z0048169biological_processregulation of long-term neuronal synaptic plasticity
Z0048471cellular_componentperinuclear region of cytoplasm
Z0048487molecular_functionbeta-tubulin binding
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Z0048489biological_processsynaptic vesicle transport
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Z0050806biological_processpositive regulation of synaptic transmission
Z0050808biological_processsynapse organization
Z0050812biological_processregulation of acyl-CoA biosynthetic process
Z0051219molecular_functionphosphoprotein binding
Z0051259biological_processprotein complex oligomerization
Z0051262biological_processprotein tetramerization
Z0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
Z0051402biological_processneuron apoptotic process
Z0051583biological_processdopamine uptake involved in synaptic transmission
Z0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
Z0051612biological_processnegative regulation of serotonin uptake
Z0051621biological_processregulation of norepinephrine uptake
Z0051622biological_processnegative regulation of norepinephrine uptake
Z0055074biological_processcalcium ion homeostasis
Z0060079biological_processexcitatory postsynaptic potential
Z0060090molecular_functionmolecular adaptor activity
Z0060291biological_processlong-term synaptic potentiation
Z0060732biological_processpositive regulation of inositol phosphate biosynthetic process
Z0060961molecular_functionphospholipase D inhibitor activity
Z0061024biological_processmembrane organization
Z0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
Z0070507biological_processregulation of microtubule cytoskeleton organization
Z0070555biological_processresponse to interleukin-1
Z0070840molecular_functiondynein complex binding
Z0071280biological_processcellular response to copper ion
Z0071872biological_processcellular response to epinephrine stimulus
Z0097435biological_processsupramolecular fiber organization
Z0098793cellular_componentpresynapse
Z0098794cellular_componentpostsynapse
Z0099512cellular_componentsupramolecular fiber
Z0140311molecular_functionprotein sequestering activity
Z0141108molecular_functiontransporter regulator activity
Z1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
Z1903136molecular_functioncuprous ion binding
Z1903285biological_processpositive regulation of hydrogen peroxide catabolic process
Z1903421biological_processregulation of synaptic vesicle recycling
Z1903426biological_processregulation of reactive oxygen species biosynthetic process
Z1904307biological_processresponse to desipramine
Z1904377biological_processpositive regulation of protein localization to cell periphery
Z1904715biological_processnegative regulation of chaperone-mediated autophagy
Z1905606biological_processregulation of presynapse assembly
Z1990000biological_processamyloid fibril formation
Z2000377biological_processregulation of reactive oxygen species metabolic process
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues110
DetailsRepeat: {"description":"1"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues110
DetailsRepeat: {"description":"2"}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues308
DetailsRepeat: {"description":"3; approximate"}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues220
DetailsRepeat: {"description":"4"}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues517
DetailsRegion: {"description":"4 X 11 AA tandem repeats of [EGS]-K-T-K-[EQ]-[GQ]-V-X(4)"}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues22
DetailsBinding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}
ChainResidueDetails

site_idSWS_FT_FI7
Number of Residues22
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"10617630","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

238895

PDB entries from 2025-07-16

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