9C8V
Human DNA polymerase alpha/primase - CHAPSO (4 mM)
Functional Information from PROSITE/UniProt
| site_id | PS00116 |
| Number of Residues | 9 |
| Details | DNA_POLYMERASE_B DNA polymerase family B signature. YGDTDSIMI |
| Chain | Residue | Details |
| C | TYR1000-ILE1008 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 35 |
| Details | ZN_FING: CysA-type => ECO:0000250|UniProtKB:P15436 |
| Chain | Residue | Details |
| C | CYS1283-SER1318 | |
| B | CYS367 | |
| B | CYS424 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:26975377, ECO:0007744|PDB:5EXR |
| Chain | Residue | Details |
| C | CYS1283 | |
| C | CYS1286 | |
| C | CYS1310 | |
| C | CYS1315 | |
| C | CYS1348 | |
| C | CYS1353 | |
| C | CYS1371 | |
| C | CYS1374 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| C | THR406 | |
| A | CYS122 | |
| A | CYS128 | |
| A | CYS131 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P33609 |
| Chain | Residue | Details |
| C | LYS970 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:24043831, ECO:0000269|PubMed:31479243 |
| Chain | Residue | Details |
| A | HIS315 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31479243 |
| Chain | Residue | Details |
| A | HIS324 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylmethionine => ECO:0007744|PubMed:22223895 |
| Chain | Residue | Details |
| A | MET1 |
