9C7T
PP2A:B55-Eya3 substrate complex
Functional Information from PROSITE/UniProt
| site_id | PS00125 |
| Number of Residues | 6 |
| Details | SER_THR_PHOSPHATASE Serine/threonine specific protein phosphatases signature. LRGNHE |
| Chain | Residue | Details |
| C | LEU114-GLU119 |
| site_id | PS01024 |
| Number of Residues | 15 |
| Details | PR55_1 Protein phosphatase 2A regulatory subunit PR55 signature 1. EFDYLKSLEIEEKIN |
| Chain | Residue | Details |
| B | GLU83-ASN97 |
| site_id | PS01025 |
| Number of Residues | 15 |
| Details | PR55_2 Protein phosphatase 2A regulatory subunit PR55 signature 2. NAHTYHINSISINSD |
| Chain | Residue | Details |
| B | ASN174-ASP188 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000250|UniProtKB:P36873 |
| Chain | Residue | Details |
| C | HIS118 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:38123684, ECO:0007744|PDB:8SO0, ECO:0007744|PDB:8TTB |
| Chain | Residue | Details |
| C | ASP57 | |
| C | HIS59 | |
| C | ASP85 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17055435, ECO:0000269|PubMed:33243860, ECO:0000269|PubMed:33633399, ECO:0000269|PubMed:34762484, ECO:0007744|PDB:7CUN, ECO:0007744|PDB:7K36, ECO:0007744|PDB:7PKS |
| Chain | Residue | Details |
| C | ASN117 | |
| C | HIS167 | |
| C | HIS241 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P67774 |
| Chain | Residue | Details |
| C | TYR307 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Leucine methyl ester => ECO:0000269|PubMed:38123684, ECO:0000269|PubMed:8206937, ECO:0007744|PDB:8SO0, ECO:0007744|PDB:8TTB |
| Chain | Residue | Details |
| C | MLL309 |
