Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9C58

AP-3 bound to myristoylated Arf1 (Q71L)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0002090	biological_process	regulation of receptor internalization
A	0003723	molecular_function	RNA binding
A	0003924	molecular_function	GTPase activity
A	0003925	molecular_function	G protein activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005794	cellular_component	Golgi apparatus
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0005925	cellular_component	focal adhesion
A	0006878	biological_process	intracellular copper ion homeostasis
A	0006886	biological_process	intracellular protein transport
A	0012505	cellular_component	endomembrane system
A	0014069	cellular_component	postsynaptic density
A	0015031	biological_process	protein transport
A	0016192	biological_process	vesicle-mediated transport
A	0016787	molecular_function	hydrolase activity
A	0019904	molecular_function	protein domain specific binding
A	0030017	cellular_component	sarcomere
A	0031252	cellular_component	cell leading edge
A	0032991	cellular_component	protein-containing complex
A	0034315	biological_process	regulation of Arp2/3 complex-mediated actin nucleation
A	0043005	cellular_component	neuron projection
A	0045202	cellular_component	synapse
A	0060292	biological_process	long-term synaptic depression
A	0070062	cellular_component	extracellular exosome
A	0097061	biological_process	dendritic spine organization
A	0098586	biological_process	cellular response to virus
A	1990386	biological_process	mitotic cleavage furrow ingression
B	0006886	biological_process	intracellular protein transport
B	0015031	biological_process	protein transport
B	0016192	biological_process	vesicle-mediated transport
B	0030117	cellular_component	membrane coat
B	0030276	molecular_function	clathrin binding
D	0006886	biological_process	intracellular protein transport
D	0015031	biological_process	protein transport
D	0016192	biological_process	vesicle-mediated transport
D	0030117	cellular_component	membrane coat
D	0030123	cellular_component	AP-3 adaptor complex
M	0005515	molecular_function	protein binding
M	0005737	cellular_component	cytoplasm
M	0005764	cellular_component	lysosome
M	0005765	cellular_component	lysosomal membrane
M	0005769	cellular_component	early endosome
M	0005794	cellular_component	Golgi apparatus
M	0005802	cellular_component	trans-Golgi network
M	0006622	biological_process	protein targeting to lysosome
M	0006886	biological_process	intracellular protein transport
M	0006896	biological_process	Golgi to vacuole transport
M	0006897	biological_process	endocytosis
M	0008089	biological_process	anterograde axonal transport
M	0015031	biological_process	protein transport
M	0016192	biological_process	vesicle-mediated transport
M	0030121	cellular_component	AP-1 adaptor complex
M	0030131	cellular_component	clathrin adaptor complex
M	0030659	cellular_component	cytoplasmic vesicle membrane
M	0031267	molecular_function	small GTPase binding
M	0031410	cellular_component	cytoplasmic vesicle
M	0035615	molecular_function	clathrin adaptor activity
M	0035654	biological_process	clathrin-coated vesicle cargo loading, AP-3-mediated
M	0048490	biological_process	anterograde synaptic vesicle transport
M	0060155	biological_process	platelet dense granule organization
M	0098837	cellular_component	postsynaptic recycling endosome
M	0098884	biological_process	postsynaptic neurotransmitter receptor internalization
M	1903232	biological_process	melanosome assembly
M	1904115	cellular_component	axon cytoplasm
S	0005515	molecular_function	protein binding
S	0005769	cellular_component	early endosome
S	0005794	cellular_component	Golgi apparatus
S	0006886	biological_process	intracellular protein transport
S	0006896	biological_process	Golgi to vacuole transport
S	0008089	biological_process	anterograde axonal transport
S	0008286	biological_process	insulin receptor signaling pathway
S	0015031	biological_process	protein transport
S	0016020	cellular_component	membrane
S	0016183	biological_process	synaptic vesicle coating
S	0016192	biological_process	vesicle-mediated transport
S	0030117	cellular_component	membrane coat
S	0030119	cellular_component	AP-type membrane coat adaptor complex
S	0030123	cellular_component	AP-3 adaptor complex
S	0030133	cellular_component	transport vesicle
S	0030659	cellular_component	cytoplasmic vesicle membrane
S	0031410	cellular_component	cytoplasmic vesicle
S	0035654	biological_process	clathrin-coated vesicle cargo loading, AP-3-mediated
S	0036465	biological_process	synaptic vesicle recycling
S	0048490	biological_process	anterograde synaptic vesicle transport
S	0060155	biological_process	platelet dense granule organization
S	0098793	cellular_component	presynapse
S	1903232	biological_process	melanosome assembly
S	1904115	cellular_component	axon cytoplasm

Functional Information from PROSITE/UniProt

site_id	PS00989
Number of Residues	11
Details	CLAT_ADAPTOR_S Clathrin adaptor complexes small chain signature. LIYRhyatLYF

Chain	Residue	Details
S	LEU63-PHE73

site_id	PS00990
Number of Residues	21
Details	CLAT_ADAPTOR_M_1 Clathrin adaptor complexes medium chain signature 1. IPWRra.GvkYtnNeAYFDVVE

Chain	Residue	Details
M	ILE165-GLU185

site_id	PS00991
Number of Residues	15
Details	CLAT_ADAPTOR_M_2 Clathrin adaptor complexes medium chain signature 2. LsFIPPdGnFrLisY

Chain	Residue	Details
M	LEU248-TYR262

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	37
Details	Repeat: {"description":"HEAT 1"}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	37
Details	Repeat: {"description":"HEAT 2"}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	37
Details	Repeat: {"description":"HEAT 3"}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	36
Details	Repeat: {"description":"HEAT 4"}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	38
Details	Repeat: {"description":"HEAT 5"}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	37
Details	Repeat: {"description":"HEAT 6"}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	35
Details	Repeat: {"description":"HEAT 7"}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	34
Details	Repeat: {"description":"HEAT 8"}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	37
Details	Repeat: {"description":"HEAT 9"}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	38
Details	Repeat: {"description":"HEAT 10"}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	37
Details	Repeat: {"description":"HEAT 11"}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17081983","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"7990966","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1HUR","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14690595","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15308674","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7990966","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2010","submissionDatabase":"PDB data bank","title":"Crystal structure of ARFGAP1-ARF1 fusion protein.","authoringGroup":["Structural genomics consortium (SGC)."]}},{"source":"PDB","id":"1HUR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RE0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1U81","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3O47","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15308674","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7990966","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2010","submissionDatabase":"PDB data bank","title":"Crystal structure of ARFGAP1-ARF1 fusion protein.","authoringGroup":["Structural genomics consortium (SGC)."]}},{"source":"PDB","id":"1HUR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RE0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3O47","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)