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9C4E

Structure of endogenous DPYSL2 from rat model of Alzheimer's disease

Functional Information from GO Data
ChainGOidnamespacecontents
A0001975biological_processresponse to amphetamine
A0004157molecular_functiondihydropyrimidinase activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0005874cellular_componentmicrotubule
A0005886cellular_componentplasma membrane
A0005929cellular_componentcilium
A0006208biological_processpyrimidine nucleobase catabolic process
A0006897biological_processendocytosis
A0007010biological_processcytoskeleton organization
A0007399biological_processnervous system development
A0009410biological_processresponse to xenobiotic stimulus
A0010975biological_processregulation of neuron projection development
A0014049biological_processpositive regulation of glutamate secretion
A0014069cellular_componentpostsynaptic density
A0015630cellular_componentmicrotubule cytoskeleton
A0016020cellular_componentmembrane
A0016787molecular_functionhydrolase activity
A0016810molecular_functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
A0016812molecular_functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A0019901molecular_functionprotein kinase binding
A0021510biological_processspinal cord development
A0021772biological_processolfactory bulb development
A0030154biological_processcell differentiation
A0030424cellular_componentaxon
A0030425cellular_componentdendrite
A0030426cellular_componentgrowth cone
A0030516biological_processregulation of axon extension
A0032991cellular_componentprotein-containing complex
A0042220biological_processresponse to cocaine
A0042802molecular_functionidentical protein binding
A0043025cellular_componentneuronal cell body
A0043195cellular_componentterminal bouton
A0043209cellular_componentmyelin sheath
A0045202cellular_componentsynapse
A0045664biological_processregulation of neuron differentiation
A0048489biological_processsynaptic vesicle transport
A0072686cellular_componentmitotic spindle
A0098685cellular_componentSchaffer collateral - CA1 synapse
A0098793cellular_componentpresynapse
A0098978cellular_componentglutamatergic synapse
A0120025cellular_componentplasma membrane bounded cell projection
A0150052biological_processregulation of postsynapse assembly
B0001975biological_processresponse to amphetamine
B0004157molecular_functiondihydropyrimidinase activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005856cellular_componentcytoskeleton
B0005874cellular_componentmicrotubule
B0005886cellular_componentplasma membrane
B0005929cellular_componentcilium
B0006208biological_processpyrimidine nucleobase catabolic process
B0006897biological_processendocytosis
B0007010biological_processcytoskeleton organization
B0007399biological_processnervous system development
B0009410biological_processresponse to xenobiotic stimulus
B0010975biological_processregulation of neuron projection development
B0014049biological_processpositive regulation of glutamate secretion
B0014069cellular_componentpostsynaptic density
B0015630cellular_componentmicrotubule cytoskeleton
B0016020cellular_componentmembrane
B0016787molecular_functionhydrolase activity
B0016810molecular_functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
B0016812molecular_functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B0019901molecular_functionprotein kinase binding
B0021510biological_processspinal cord development
B0021772biological_processolfactory bulb development
B0030154biological_processcell differentiation
B0030424cellular_componentaxon
B0030425cellular_componentdendrite
B0030426cellular_componentgrowth cone
B0030516biological_processregulation of axon extension
B0032991cellular_componentprotein-containing complex
B0042220biological_processresponse to cocaine
B0042802molecular_functionidentical protein binding
B0043025cellular_componentneuronal cell body
B0043195cellular_componentterminal bouton
B0043209cellular_componentmyelin sheath
B0045202cellular_componentsynapse
B0045664biological_processregulation of neuron differentiation
B0048489biological_processsynaptic vesicle transport
B0072686cellular_componentmitotic spindle
B0098685cellular_componentSchaffer collateral - CA1 synapse
B0098793cellular_componentpresynapse
B0098978cellular_componentglutamatergic synapse
B0120025cellular_componentplasma membrane bounded cell projection
B0150052biological_processregulation of postsynapse assembly
C0001975biological_processresponse to amphetamine
C0004157molecular_functiondihydropyrimidinase activity
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0005856cellular_componentcytoskeleton
C0005874cellular_componentmicrotubule
C0005886cellular_componentplasma membrane
C0005929cellular_componentcilium
C0006208biological_processpyrimidine nucleobase catabolic process
C0006897biological_processendocytosis
C0007010biological_processcytoskeleton organization
C0007399biological_processnervous system development
C0009410biological_processresponse to xenobiotic stimulus
C0010975biological_processregulation of neuron projection development
C0014049biological_processpositive regulation of glutamate secretion
C0014069cellular_componentpostsynaptic density
C0015630cellular_componentmicrotubule cytoskeleton
C0016020cellular_componentmembrane
C0016787molecular_functionhydrolase activity
C0016810molecular_functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
C0016812molecular_functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C0019901molecular_functionprotein kinase binding
C0021510biological_processspinal cord development
C0021772biological_processolfactory bulb development
C0030154biological_processcell differentiation
C0030424cellular_componentaxon
C0030425cellular_componentdendrite
C0030426cellular_componentgrowth cone
C0030516biological_processregulation of axon extension
C0032991cellular_componentprotein-containing complex
C0042220biological_processresponse to cocaine
C0042802molecular_functionidentical protein binding
C0043025cellular_componentneuronal cell body
C0043195cellular_componentterminal bouton
C0043209cellular_componentmyelin sheath
C0045202cellular_componentsynapse
C0045664biological_processregulation of neuron differentiation
C0048489biological_processsynaptic vesicle transport
C0072686cellular_componentmitotic spindle
C0098685cellular_componentSchaffer collateral - CA1 synapse
C0098793cellular_componentpresynapse
C0098978cellular_componentglutamatergic synapse
C0120025cellular_componentplasma membrane bounded cell projection
C0150052biological_processregulation of postsynapse assembly
D0001975biological_processresponse to amphetamine
D0004157molecular_functiondihydropyrimidinase activity
D0005515molecular_functionprotein binding
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0005856cellular_componentcytoskeleton
D0005874cellular_componentmicrotubule
D0005886cellular_componentplasma membrane
D0005929cellular_componentcilium
D0006208biological_processpyrimidine nucleobase catabolic process
D0006897biological_processendocytosis
D0007010biological_processcytoskeleton organization
D0007399biological_processnervous system development
D0009410biological_processresponse to xenobiotic stimulus
D0010975biological_processregulation of neuron projection development
D0014049biological_processpositive regulation of glutamate secretion
D0014069cellular_componentpostsynaptic density
D0015630cellular_componentmicrotubule cytoskeleton
D0016020cellular_componentmembrane
D0016787molecular_functionhydrolase activity
D0016810molecular_functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
D0016812molecular_functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D0019901molecular_functionprotein kinase binding
D0021510biological_processspinal cord development
D0021772biological_processolfactory bulb development
D0030154biological_processcell differentiation
D0030424cellular_componentaxon
D0030425cellular_componentdendrite
D0030426cellular_componentgrowth cone
D0030516biological_processregulation of axon extension
D0032991cellular_componentprotein-containing complex
D0042220biological_processresponse to cocaine
D0042802molecular_functionidentical protein binding
D0043025cellular_componentneuronal cell body
D0043195cellular_componentterminal bouton
D0043209cellular_componentmyelin sheath
D0045202cellular_componentsynapse
D0045664biological_processregulation of neuron differentiation
D0048489biological_processsynaptic vesicle transport
D0072686cellular_componentmitotic spindle
D0098685cellular_componentSchaffer collateral - CA1 synapse
D0098793cellular_componentpresynapse
D0098978cellular_componentglutamatergic synapse
D0120025cellular_componentplasma membrane bounded cell projection
D0150052biological_processregulation of postsynapse assembly
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsSite: {"description":"Not phosphorylated"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues4
DetailsModified residue: {"description":"Phosphotyrosine; by FYN","evidences":[{"source":"UniProtKB","id":"Q16555","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues4
DetailsModified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"O08553","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues4
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"22673903","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues8
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"O08553","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues4
DetailsModified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"O08553","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

244693

PDB entries from 2025-11-12

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