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9C4B

Second BAF53a of the human TIP60 complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0000723biological_processtelomere maintenance
A0000776cellular_componentkinetochore
A0000785cellular_componentchromatin
A0000786cellular_componentnucleosome
A0001825biological_processblastocyst formation
A0003407biological_processneural retina development
A0003682molecular_functionchromatin binding
A0003713molecular_functiontranscription coactivator activity
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005886cellular_componentplasma membrane
A0006275biological_processregulation of DNA replication
A0006281biological_processDNA repair
A0006282biological_processregulation of DNA repair
A0006310biological_processDNA recombination
A0006325biological_processchromatin organization
A0006338biological_processchromatin remodeling
A0006355biological_processregulation of DNA-templated transcription
A0006357biological_processregulation of transcription by RNA polymerase II
A0006974biological_processDNA damage response
A0007165biological_processsignal transduction
A0007399biological_processnervous system development
A0008284biological_processpositive regulation of cell population proliferation
A0016363cellular_componentnuclear matrix
A0016514cellular_componentSWI/SNF complex
A0016586cellular_componentRSC-type complex
A0021510biological_processspinal cord development
A0030071biological_processregulation of mitotic metaphase/anaphase transition
A0031011cellular_componentIno80 complex
A0031492molecular_functionnucleosomal DNA binding
A0032991cellular_componentprotein-containing complex
A0033044biological_processregulation of chromosome organization
A0035060cellular_componentbrahma complex
A0035267cellular_componentNuA4 histone acetyltransferase complex
A0042981biological_processregulation of apoptotic process
A0045582biological_processpositive regulation of T cell differentiation
A0045596biological_processnegative regulation of cell differentiation
A0045597biological_processpositive regulation of cell differentiation
A0045663biological_processpositive regulation of myoblast differentiation
A0045739biological_processpositive regulation of DNA repair
A0045893biological_processpositive regulation of DNA-templated transcription
A0045995biological_processregulation of embryonic development
A0048731biological_processsystem development
A0051726biological_processregulation of cell cycle
A0060382biological_processregulation of DNA strand elongation
A0070316biological_processregulation of G0 to G1 transition
A0071564cellular_componentnpBAF complex
A0140288cellular_componentGBAF complex
A1902459biological_processpositive regulation of stem cell population maintenance
A1904507biological_processpositive regulation of telomere maintenance in response to DNA damage
A1905168biological_processpositive regulation of double-strand break repair via homologous recombination
A2000045biological_processregulation of G1/S transition of mitotic cell cycle
A2000779biological_processregulation of double-strand break repair
A2000781biological_processpositive regulation of double-strand break repair
A2000819biological_processregulation of nucleotide-excision repair
Functional Information from PROSITE/UniProt
site_idPS00141
Number of Residues12
DetailsASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LILDSGATHTTA
ChainResidueDetails
ALEU168-ALA179

site_idPS00432
Number of Residues9
DetailsACTINS_2 Actins signature 2. WISKqEYEE
ChainResidueDetails
ATRP410-GLU418

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N-acetylserine => ECO:0000269|Ref.8, ECO:0007744|PubMed:22814378
ChainResidueDetails
ASER2

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER86

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER233

site_idSWS_FT_FI4
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
ALYS62

237735

PDB entries from 2025-06-18

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