9C47

TRRAP module of the human TIP60 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0000124	cellular_component	SAGA complex
C	0000786	cellular_component	nucleosome
C	0000812	cellular_component	Swr1 complex
C	0003712	molecular_function	transcription coregulator activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005794	cellular_component	Golgi apparatus
C	0006282	biological_process	regulation of DNA repair
C	0006325	biological_process	chromatin organization
C	0006355	biological_process	regulation of DNA-templated transcription
C	0006357	biological_process	regulation of transcription by RNA polymerase II
C	0016301	molecular_function	kinase activity
C	0033276	cellular_component	transcription factor TFTC complex
C	0035267	cellular_component	NuA4 histone acetyltransferase complex
C	0042981	biological_process	regulation of apoptotic process
C	0043484	biological_process	regulation of RNA splicing
C	0045893	biological_process	positive regulation of DNA-templated transcription
C	0051726	biological_process	regulation of cell cycle
C	0080135	biological_process	regulation of cellular response to stress
C	0140861	biological_process	DNA repair-dependent chromatin remodeling
C	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
C	2000779	biological_process	regulation of double-strand break repair
G	0000166	molecular_function	nucleotide binding
G	0000786	cellular_component	nucleosome
G	0000812	cellular_component	Swr1 complex
G	0003677	molecular_function	DNA binding
G	0003682	molecular_function	chromatin binding
G	0004386	molecular_function	helicase activity
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0006281	biological_process	DNA repair
G	0006325	biological_process	chromatin organization
G	0016607	cellular_component	nuclear speck
G	0016787	molecular_function	hydrolase activity
G	0035267	cellular_component	NuA4 histone acetyltransferase complex
G	0042981	biological_process	regulation of apoptotic process
G	0045893	biological_process	positive regulation of DNA-templated transcription
G	0051726	biological_process	regulation of cell cycle
G	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
G	1990405	molecular_function	protein antigen binding
G	2000779	biological_process	regulation of double-strand break repair

Functional Information from PROSITE/UniProt

site_id	PS00196
Number of Residues	15
Details	COPPER_BLUE Type-1 copper (blue) proteins signature. GeiSpFLCs.GsHqv..Q

Chain	Residue	Details
C	GLY2650-GLN2664

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Domain: {"description":"FATC","evidences":[{"source":"PROSITE-ProRule","id":"PRU00534","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU00535","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Region: {"description":"G-loop","evidences":[{"source":"PROSITE-ProRule","id":"PRU00269","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Region: {"description":"Catalytic loop","evidences":[{"source":"PROSITE-ProRule","id":"PRU00269","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	25
Details	Region: {"description":"Activation loop","evidences":[{"source":"PROSITE-ProRule","id":"PRU00269","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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