9BYK

Cryo-EM structure of ATP synthase E state

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
8	0006754	biological_process	ATP biosynthetic process
8	0006811	biological_process	monoatomic ion transport
8	0031966	cellular_component	mitochondrial membrane
8	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
8	0045259	cellular_component	proton-transporting ATP synthase complex
8	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
8	1902600	biological_process	proton transmembrane transport
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0005886	cellular_component	plasma membrane
A	0006754	biological_process	ATP biosynthetic process
A	0006811	biological_process	monoatomic ion transport
A	0045259	cellular_component	proton-transporting ATP synthase complex
A	0046872	molecular_function	metal ion binding
A	1902600	biological_process	proton transmembrane transport
B	0000166	molecular_function	nucleotide binding
B	0005524	molecular_function	ATP binding
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0005886	cellular_component	plasma membrane
B	0006754	biological_process	ATP biosynthetic process
B	0006811	biological_process	monoatomic ion transport
B	0045259	cellular_component	proton-transporting ATP synthase complex
B	0046872	molecular_function	metal ion binding
B	1902600	biological_process	proton transmembrane transport
C	0000166	molecular_function	nucleotide binding
C	0005524	molecular_function	ATP binding
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0005886	cellular_component	plasma membrane
C	0006754	biological_process	ATP biosynthetic process
C	0006811	biological_process	monoatomic ion transport
C	0045259	cellular_component	proton-transporting ATP synthase complex
C	0046872	molecular_function	metal ion binding
C	1902600	biological_process	proton transmembrane transport
D	0000166	molecular_function	nucleotide binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006754	biological_process	ATP biosynthetic process
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0045259	cellular_component	proton-transporting ATP synthase complex
D	0046872	molecular_function	metal ion binding
D	1902600	biological_process	proton transmembrane transport
E	0000166	molecular_function	nucleotide binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0006754	biological_process	ATP biosynthetic process
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0045259	cellular_component	proton-transporting ATP synthase complex
E	0046872	molecular_function	metal ion binding
E	1902600	biological_process	proton transmembrane transport
F	0000166	molecular_function	nucleotide binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0006754	biological_process	ATP biosynthetic process
F	0006811	biological_process	monoatomic ion transport
F	0016020	cellular_component	membrane
F	0045259	cellular_component	proton-transporting ATP synthase complex
F	0046872	molecular_function	metal ion binding
F	1902600	biological_process	proton transmembrane transport
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0006754	biological_process	ATP biosynthetic process
G	0006811	biological_process	monoatomic ion transport
G	0045259	cellular_component	proton-transporting ATP synthase complex
G	1902600	biological_process	proton transmembrane transport
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0006754	biological_process	ATP biosynthetic process
H	0006811	biological_process	monoatomic ion transport
H	0045259	cellular_component	proton-transporting ATP synthase complex
H	1902600	biological_process	proton transmembrane transport
I	0005739	cellular_component	mitochondrion
I	0005743	cellular_component	mitochondrial inner membrane
I	0006754	biological_process	ATP biosynthetic process
I	0006811	biological_process	monoatomic ion transport
I	0045259	cellular_component	proton-transporting ATP synthase complex
I	1902600	biological_process	proton transmembrane transport
J	0001937	biological_process	negative regulation of endothelial cell proliferation
J	0002931	biological_process	response to ischemia
J	0005516	molecular_function	calmodulin binding
J	0005737	cellular_component	cytoplasm
J	0005739	cellular_component	mitochondrion
J	0006783	biological_process	heme biosynthetic process
J	0009986	cellular_component	cell surface
J	0010667	biological_process	negative regulation of cardiac muscle cell apoptotic process
J	0019899	molecular_function	enzyme binding
J	0030218	biological_process	erythrocyte differentiation
J	0032991	cellular_component	protein-containing complex
J	0042030	molecular_function	ATPase inhibitor activity
J	0042802	molecular_function	identical protein binding
J	0043532	molecular_function	angiostatin binding
J	0051117	molecular_function	ATPase binding
J	0051346	biological_process	negative regulation of hydrolase activity
J	0051882	biological_process	mitochondrial depolarization
J	0140260	molecular_function	mitochondrial proton-transporting ATP synthase complex binding
J	1903052	biological_process	positive regulation of proteolysis involved in protein catabolic process
J	1903214	biological_process	regulation of protein targeting to mitochondrion
J	1903578	biological_process	regulation of ATP metabolic process
J	1905091	biological_process	positive regulation of type 2 mitophagy
J	1905707	biological_process	negative regulation of mitochondrial ATP synthesis coupled proton transport
S	0005743	cellular_component	mitochondrial inner membrane
S	0006754	biological_process	ATP biosynthetic process
S	0006811	biological_process	monoatomic ion transport
S	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
S	0045259	cellular_component	proton-transporting ATP synthase complex
S	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
S	1902600	biological_process	proton transmembrane transport
T	0006754	biological_process	ATP biosynthetic process
T	0006811	biological_process	monoatomic ion transport
T	0015078	molecular_function	proton transmembrane transporter activity
T	0015986	biological_process	proton motive force-driven ATP synthesis
T	0031966	cellular_component	mitochondrial membrane
T	0045259	cellular_component	proton-transporting ATP synthase complex
T	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
T	1902600	biological_process	proton transmembrane transport
a	0005743	cellular_component	mitochondrial inner membrane
a	0006754	biological_process	ATP biosynthetic process
a	0006811	biological_process	monoatomic ion transport
a	0015252	molecular_function	proton channel activity
a	0015986	biological_process	proton motive force-driven ATP synthesis
a	0045259	cellular_component	proton-transporting ATP synthase complex
a	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
a	1902600	biological_process	proton transmembrane transport
b	0005739	cellular_component	mitochondrion
b	0005743	cellular_component	mitochondrial inner membrane
b	0006811	biological_process	monoatomic ion transport
b	0015078	molecular_function	proton transmembrane transporter activity
b	0015986	biological_process	proton motive force-driven ATP synthesis
b	0045259	cellular_component	proton-transporting ATP synthase complex
b	1902600	biological_process	proton transmembrane transport
c	0005739	cellular_component	mitochondrion
c	0005743	cellular_component	mitochondrial inner membrane
c	0006811	biological_process	monoatomic ion transport
c	0045259	cellular_component	proton-transporting ATP synthase complex
c	1902600	biological_process	proton transmembrane transport
d	0005743	cellular_component	mitochondrial inner membrane
d	0006811	biological_process	monoatomic ion transport
d	0015986	biological_process	proton motive force-driven ATP synthesis
d	0045259	cellular_component	proton-transporting ATP synthase complex
d	1902600	biological_process	proton transmembrane transport
e	0005739	cellular_component	mitochondrion
e	0005743	cellular_component	mitochondrial inner membrane
e	0006754	biological_process	ATP biosynthetic process
e	0006811	biological_process	monoatomic ion transport
e	0016020	cellular_component	membrane
e	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
e	0045259	cellular_component	proton-transporting ATP synthase complex
e	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
e	1902600	biological_process	proton transmembrane transport
f	0005739	cellular_component	mitochondrion
f	0005743	cellular_component	mitochondrial inner membrane
f	0006754	biological_process	ATP biosynthetic process
f	0006811	biological_process	monoatomic ion transport
f	0045259	cellular_component	proton-transporting ATP synthase complex
f	1902600	biological_process	proton transmembrane transport
i	0005739	cellular_component	mitochondrion
i	0031966	cellular_component	mitochondrial membrane
i	0045259	cellular_component	proton-transporting ATP synthase complex

Functional Information from PROSITE/UniProt

site_id	PS00152
Number of Residues	10
Details	ATPASE_ALPHA_BETA ATP synthase alpha and beta subunits signature. PAINVGLSVS

Chain	Residue	Details
C	PRO363-SER372
D	PRO348-SER357

---

site_id	PS00153
Number of Residues	14
Details	ATPASE_GAMMA ATP synthase gamma subunit signature. ITkEliEiisGAaA

Chain	Residue	Details
G	ILE258-ALA271

---

site_id	PS00389
Number of Residues	20
Details	ATPASE_DELTA ATP synthase delta (OSCP) subunit signature. LkLevkVDpSImGGMIVRiG

Chain	Residue	Details
S	LEU148-GLY167

---

site_id	PS00449
Number of Residues	10
Details	ATPASE_A ATP synthase a subunit signature. ALAVRLTANI

Chain	Residue	Details
a	ALA155-ILE164

---

site_id	PS00605
Number of Residues	22
Details	ATPASE_C ATP synthase c subunit signature. ARNPslkqqLfSyaILgfaLsE

Chain	Residue	Details
K	ALA37-GLU58

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	116
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	3
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P18859","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P97450","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P97450","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P21571","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q06185","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	17
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"UniProtKB","id":"P56134","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"UniProtKB","id":"P56134","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"D3ZAF6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P56135","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---