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9BW6

Human Vault Cage in complex with PARP4

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005634cellular_componentnucleus
A0005643cellular_componentnuclear pore
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0008283biological_processcell population proliferation
A0015031biological_processprotein transport
A0016020cellular_componentmembrane
A0019901molecular_functionprotein kinase binding
A0019903molecular_functionprotein phosphatase binding
A0031953biological_processnegative regulation of protein autophosphorylation
A0034774cellular_componentsecretory granule lumen
A0038127biological_processERBB signaling pathway
A0042059biological_processnegative regulation of epidermal growth factor receptor signaling pathway
A0042802molecular_functionidentical protein binding
A0048471cellular_componentperinuclear region of cytoplasm
A0051028biological_processmRNA transport
A0061099biological_processnegative regulation of protein tyrosine kinase activity
A0070062cellular_componentextracellular exosome
A0072376biological_processprotein activation cascade
A1904813cellular_componentficolin-1-rich granule lumen
A1990904cellular_componentribonucleoprotein complex
B0003677molecular_functionDNA binding
B0003950molecular_functionNAD+ poly-ADP-ribosyltransferase activity
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005819cellular_componentspindle
B0005829cellular_componentcytosol
B0005856cellular_componentcytoskeleton
B0005876cellular_componentspindle microtubule
B0006281biological_processDNA repair
B0006954biological_processinflammatory response
B0006974biological_processDNA damage response
B0009410biological_processresponse to xenobiotic stimulus
B0016020cellular_componentmembrane
B0016740molecular_functiontransferase activity
B0016757molecular_functionglycosyltransferase activity
B0016779molecular_functionnucleotidyltransferase activity
B0019899molecular_functionenzyme binding
B0036211biological_processprotein modification process
B0070062cellular_componentextracellular exosome
B0140289biological_processobsolete protein mono-ADP-ribosylation
B0140806molecular_functionNAD+-protein-aspartate ADP-ribosyltransferase activity
B0140807molecular_functionNAD+-protein-glutamate ADP-ribosyltransferase activity
B1990404molecular_functionNAD+-protein mono-ADP-ribosyltransferase activity
B1990904cellular_componentribonucleoprotein complex
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005634cellular_componentnucleus
C0005643cellular_componentnuclear pore
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0005856cellular_componentcytoskeleton
C0008283biological_processcell population proliferation
C0015031biological_processprotein transport
C0016020cellular_componentmembrane
C0019901molecular_functionprotein kinase binding
C0019903molecular_functionprotein phosphatase binding
C0031953biological_processnegative regulation of protein autophosphorylation
C0034774cellular_componentsecretory granule lumen
C0038127biological_processERBB signaling pathway
C0042059biological_processnegative regulation of epidermal growth factor receptor signaling pathway
C0042802molecular_functionidentical protein binding
C0048471cellular_componentperinuclear region of cytoplasm
C0051028biological_processmRNA transport
C0061099biological_processnegative regulation of protein tyrosine kinase activity
C0070062cellular_componentextracellular exosome
C0072376biological_processprotein activation cascade
C1904813cellular_componentficolin-1-rich granule lumen
C1990904cellular_componentribonucleoprotein complex
D0003677molecular_functionDNA binding
D0003950molecular_functionNAD+ poly-ADP-ribosyltransferase activity
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005654cellular_componentnucleoplasm
D0005737cellular_componentcytoplasm
D0005819cellular_componentspindle
D0005829cellular_componentcytosol
D0005856cellular_componentcytoskeleton
D0005876cellular_componentspindle microtubule
D0006281biological_processDNA repair
D0006954biological_processinflammatory response
D0006974biological_processDNA damage response
D0009410biological_processresponse to xenobiotic stimulus
D0016020cellular_componentmembrane
D0016740molecular_functiontransferase activity
D0016757molecular_functionglycosyltransferase activity
D0016779molecular_functionnucleotidyltransferase activity
D0019899molecular_functionenzyme binding
D0036211biological_processprotein modification process
D0070062cellular_componentextracellular exosome
D0140289biological_processobsolete protein mono-ADP-ribosylation
D0140806molecular_functionNAD+-protein-aspartate ADP-ribosyltransferase activity
D0140807molecular_functionNAD+-protein-glutamate ADP-ribosyltransferase activity
D1990404molecular_functionNAD+-protein mono-ADP-ribosyltransferase activity
D1990904cellular_componentribonucleoprotein complex
Functional Information from PROSITE/UniProt
site_idPS00018
Number of Residues13
DetailsEF_HAND_1 EF-hand calcium-binding domain. DKDGDKVVAgdEW
ChainResidueDetails
AASP131-TRP143

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues108
DetailsRepeat: {"description":"MVP 2"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues104
DetailsRepeat: {"description":"MVP 3"}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues104
DetailsRepeat: {"description":"MVP 4"}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues108
DetailsRepeat: {"description":"MVP 5"}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues100
DetailsRepeat: {"description":"MVP 6"}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues110
DetailsRepeat: {"description":"MVP 7"}
ChainResidueDetails

site_idSWS_FT_FI7
Number of Residues124
DetailsRepeat: {"description":"MVP 9"}
ChainResidueDetails

site_idSWS_FT_FI8
Number of Residues4
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

239149

PDB entries from 2025-07-23

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