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9BW5

Human Vault Cage

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005634cellular_componentnucleus
A0005643cellular_componentnuclear pore
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0008283biological_processcell population proliferation
A0015031biological_processprotein transport
A0016020cellular_componentmembrane
A0019901molecular_functionprotein kinase binding
A0019903molecular_functionprotein phosphatase binding
A0031953biological_processnegative regulation of protein autophosphorylation
A0034774cellular_componentsecretory granule lumen
A0038127biological_processERBB signaling pathway
A0042059biological_processnegative regulation of epidermal growth factor receptor signaling pathway
A0042802molecular_functionidentical protein binding
A0048471cellular_componentperinuclear region of cytoplasm
A0051028biological_processmRNA transport
A0061099biological_processnegative regulation of protein tyrosine kinase activity
A0070062cellular_componentextracellular exosome
A0072376biological_processprotein activation cascade
A1904813cellular_componentficolin-1-rich granule lumen
A1990904cellular_componentribonucleoprotein complex
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005634cellular_componentnucleus
B0005643cellular_componentnuclear pore
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005856cellular_componentcytoskeleton
B0008283biological_processcell population proliferation
B0015031biological_processprotein transport
B0016020cellular_componentmembrane
B0019901molecular_functionprotein kinase binding
B0019903molecular_functionprotein phosphatase binding
B0031953biological_processnegative regulation of protein autophosphorylation
B0034774cellular_componentsecretory granule lumen
B0038127biological_processERBB signaling pathway
B0042059biological_processnegative regulation of epidermal growth factor receptor signaling pathway
B0042802molecular_functionidentical protein binding
B0048471cellular_componentperinuclear region of cytoplasm
B0051028biological_processmRNA transport
B0061099biological_processnegative regulation of protein tyrosine kinase activity
B0070062cellular_componentextracellular exosome
B0072376biological_processprotein activation cascade
B1904813cellular_componentficolin-1-rich granule lumen
B1990904cellular_componentribonucleoprotein complex
Functional Information from PROSITE/UniProt
site_idPS00018
Number of Residues13
DetailsEF_HAND_1 EF-hand calcium-binding domain. DKDGDKVVAgdEW
ChainResidueDetails
AASP131-TRP143

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues108
DetailsRepeat: {"description":"MVP 2"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues104
DetailsRepeat: {"description":"MVP 3"}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues104
DetailsRepeat: {"description":"MVP 4"}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues108
DetailsRepeat: {"description":"MVP 5"}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues100
DetailsRepeat: {"description":"MVP 6"}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues110
DetailsRepeat: {"description":"MVP 7"}
ChainResidueDetails

site_idSWS_FT_FI7
Number of Residues124
DetailsRepeat: {"description":"MVP 9"}
ChainResidueDetails

site_idSWS_FT_FI8
Number of Residues4
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

239149

PDB entries from 2025-07-23

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