9BV2

M2B Midnolin-Proteasome (translocating)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000502	cellular_component	proteasome complex
A	0000932	cellular_component	P-body
A	0001649	biological_process	osteoblast differentiation
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005576	cellular_component	extracellular region
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006511	biological_process	ubiquitin-dependent protein catabolic process
A	0006979	biological_process	response to oxidative stress
A	0008021	cellular_component	synaptic vesicle
A	0008540	cellular_component	proteasome regulatory particle, base subcomplex
A	0010498	biological_process	proteasomal protein catabolic process
A	0016020	cellular_component	membrane
A	0016887	molecular_function	ATP hydrolysis activity
A	0022624	cellular_component	proteasome accessory complex
A	0034774	cellular_component	secretory granule lumen
A	0036402	molecular_function	proteasome-activating activity
A	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
A	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
A	0061136	biological_process	regulation of proteasomal protein catabolic process
A	0071357	biological_process	cellular response to type I interferon
A	1901800	biological_process	positive regulation of proteasomal protein catabolic process
A	1904813	cellular_component	ficolin-1-rich granule lumen
A	2000311	biological_process	regulation of AMPA receptor activity
B	0000166	molecular_function	nucleotide binding
B	0000502	cellular_component	proteasome complex
B	0003723	molecular_function	RNA binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005838	cellular_component	proteasome regulatory particle
B	0006979	biological_process	response to oxidative stress
B	0008021	cellular_component	synaptic vesicle
B	0008540	cellular_component	proteasome regulatory particle, base subcomplex
B	0010498	biological_process	proteasomal protein catabolic process
B	0016020	cellular_component	membrane
B	0016887	molecular_function	ATP hydrolysis activity
B	0022624	cellular_component	proteasome accessory complex
B	0036402	molecular_function	proteasome-activating activity
B	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
B	0061136	biological_process	regulation of proteasomal protein catabolic process
B	0071357	biological_process	cellular response to type I interferon
B	2000311	biological_process	regulation of AMPA receptor activity
C	0000166	molecular_function	nucleotide binding
C	0000502	cellular_component	proteasome complex
C	0005102	molecular_function	signaling receptor binding
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005838	cellular_component	proteasome regulatory particle
C	0005886	cellular_component	plasma membrane
C	0006357	biological_process	regulation of transcription by RNA polymerase II
C	0006979	biological_process	response to oxidative stress
C	0008021	cellular_component	synaptic vesicle
C	0008134	molecular_function	transcription factor binding
C	0008540	cellular_component	proteasome regulatory particle, base subcomplex
C	0010498	biological_process	proteasomal protein catabolic process
C	0016020	cellular_component	membrane
C	0016234	cellular_component	inclusion body
C	0016887	molecular_function	ATP hydrolysis activity
C	0017025	molecular_function	TBP-class protein binding
C	0022624	cellular_component	proteasome accessory complex
C	0031410	cellular_component	cytoplasmic vesicle
C	0031531	molecular_function	thyrotropin-releasing hormone receptor binding
C	0031595	cellular_component	nuclear proteasome complex
C	0031597	cellular_component	cytosolic proteasome complex
C	0036402	molecular_function	proteasome-activating activity
C	0043069	biological_process	negative regulation of programmed cell death
C	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
C	0045893	biological_process	positive regulation of DNA-templated transcription
C	0061136	biological_process	regulation of proteasomal protein catabolic process
C	0070062	cellular_component	extracellular exosome
C	0071357	biological_process	cellular response to type I interferon
C	0072562	cellular_component	blood microparticle
C	0090261	biological_process	positive regulation of inclusion body assembly
C	0140296	molecular_function	general transcription initiation factor binding
C	0140297	molecular_function	DNA-binding transcription factor binding
C	1901800	biological_process	positive regulation of proteasomal protein catabolic process
C	2000311	biological_process	regulation of AMPA receptor activity
D	0000166	molecular_function	nucleotide binding
D	0000502	cellular_component	proteasome complex
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006508	biological_process	proteolysis
D	0006979	biological_process	response to oxidative stress
D	0008021	cellular_component	synaptic vesicle
D	0008540	cellular_component	proteasome regulatory particle, base subcomplex
D	0010498	biological_process	proteasomal protein catabolic process
D	0016020	cellular_component	membrane
D	0016887	molecular_function	ATP hydrolysis activity
D	0022624	cellular_component	proteasome accessory complex
D	0036402	molecular_function	proteasome-activating activity
D	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
D	0061136	biological_process	regulation of proteasomal protein catabolic process
D	0071357	biological_process	cellular response to type I interferon
D	2000311	biological_process	regulation of AMPA receptor activity
E	0000166	molecular_function	nucleotide binding
E	0000502	cellular_component	proteasome complex
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006979	biological_process	response to oxidative stress
E	0008021	cellular_component	synaptic vesicle
E	0008540	cellular_component	proteasome regulatory particle, base subcomplex
E	0010498	biological_process	proteasomal protein catabolic process
E	0016020	cellular_component	membrane
E	0016234	cellular_component	inclusion body
E	0016887	molecular_function	ATP hydrolysis activity
E	0022624	cellular_component	proteasome accessory complex
E	0030674	molecular_function	protein-macromolecule adaptor activity
E	0031597	cellular_component	cytosolic proteasome complex
E	0036402	molecular_function	proteasome-activating activity
E	0036503	biological_process	ERAD pathway
E	0042802	molecular_function	identical protein binding
E	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
E	0045899	biological_process	positive regulation of RNA polymerase II transcription preinitiation complex assembly
E	0061136	biological_process	regulation of proteasomal protein catabolic process
E	0070062	cellular_component	extracellular exosome
E	0071357	biological_process	cellular response to type I interferon
E	0090261	biological_process	positive regulation of inclusion body assembly
E	1901800	biological_process	positive regulation of proteasomal protein catabolic process
E	2000311	biological_process	regulation of AMPA receptor activity
F	0000166	molecular_function	nucleotide binding
F	0000502	cellular_component	proteasome complex
F	0000932	cellular_component	P-body
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005576	cellular_component	extracellular region
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006979	biological_process	response to oxidative stress
F	0008021	cellular_component	synaptic vesicle
F	0008540	cellular_component	proteasome regulatory particle, base subcomplex
F	0010498	biological_process	proteasomal protein catabolic process
F	0016020	cellular_component	membrane
F	0016887	molecular_function	ATP hydrolysis activity
F	0022624	cellular_component	proteasome accessory complex
F	0034774	cellular_component	secretory granule lumen
F	0036402	molecular_function	proteasome-activating activity
F	0042802	molecular_function	identical protein binding
F	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
F	0043921	biological_process	host-mediated perturbation of viral transcription
F	0045944	biological_process	positive regulation of transcription by RNA polymerase II
F	0061136	biological_process	regulation of proteasomal protein catabolic process
F	0071357	biological_process	cellular response to type I interferon
F	1901800	biological_process	positive regulation of proteasomal protein catabolic process
F	1904813	cellular_component	ficolin-1-rich granule lumen
F	2000311	biological_process	regulation of AMPA receptor activity
G	0000502	cellular_component	proteasome complex
G	0000932	cellular_component	P-body
G	0002376	biological_process	immune system process
G	0003723	molecular_function	RNA binding
G	0004175	molecular_function	endopeptidase activity
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005839	cellular_component	proteasome core complex
G	0005840	cellular_component	ribosome
G	0006281	biological_process	DNA repair
G	0006511	biological_process	ubiquitin-dependent protein catabolic process
G	0006915	biological_process	apoptotic process
G	0006974	biological_process	DNA damage response
G	0006979	biological_process	response to oxidative stress
G	0007283	biological_process	spermatogenesis
G	0008021	cellular_component	synaptic vesicle
G	0010498	biological_process	proteasomal protein catabolic process
G	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
G	0016363	cellular_component	nuclear matrix
G	0019773	cellular_component	proteasome core complex, alpha-subunit complex
G	0030016	cellular_component	myofibril
G	0030017	cellular_component	sarcomere
G	0030317	biological_process	flagellated sperm motility
G	0032729	biological_process	positive regulation of type II interferon production
G	0032743	biological_process	positive regulation of interleukin-2 production
G	0032760	biological_process	positive regulation of tumor necrosis factor production
G	0034341	biological_process	response to type II interferon
G	0034515	cellular_component	proteasome storage granule
G	0035639	molecular_function	purine ribonucleoside triphosphate binding
G	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
G	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
G	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
G	0045061	biological_process	thymic T cell selection
G	0045063	biological_process	T-helper 1 cell differentiation
G	0045590	biological_process	negative regulation of regulatory T cell differentiation
G	0050727	biological_process	regulation of inflammatory response
G	0051059	molecular_function	NF-kappaB binding
G	0051321	biological_process	meiotic cell cycle
G	0051603	biological_process	proteolysis involved in protein catabolic process
G	0061136	biological_process	regulation of proteasomal protein catabolic process
G	0070062	cellular_component	extracellular exosome
G	0071357	biological_process	cellular response to type I interferon
G	0072539	biological_process	T-helper 17 cell differentiation
G	0097229	cellular_component	sperm end piece
G	0097542	cellular_component	ciliary tip
G	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
G	1990111	cellular_component	spermatoproteasome complex
G	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
H	0000502	cellular_component	proteasome complex
H	0000932	cellular_component	P-body
H	0002376	biological_process	immune system process
H	0005515	molecular_function	protein binding
H	0005576	cellular_component	extracellular region
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005839	cellular_component	proteasome core complex
H	0006281	biological_process	DNA repair
H	0006511	biological_process	ubiquitin-dependent protein catabolic process
H	0006915	biological_process	apoptotic process
H	0006974	biological_process	DNA damage response
H	0006979	biological_process	response to oxidative stress
H	0007283	biological_process	spermatogenesis
H	0008021	cellular_component	synaptic vesicle
H	0009615	biological_process	response to virus
H	0010498	biological_process	proteasomal protein catabolic process
H	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
H	0019773	cellular_component	proteasome core complex, alpha-subunit complex
H	0030317	biological_process	flagellated sperm motility
H	0032729	biological_process	positive regulation of type II interferon production
H	0032743	biological_process	positive regulation of interleukin-2 production
H	0032760	biological_process	positive regulation of tumor necrosis factor production
H	0034341	biological_process	response to type II interferon
H	0034515	cellular_component	proteasome storage granule
H	0034774	cellular_component	secretory granule lumen
H	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
H	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
H	0045061	biological_process	thymic T cell selection
H	0045063	biological_process	T-helper 1 cell differentiation
H	0045590	biological_process	negative regulation of regulatory T cell differentiation
H	0051321	biological_process	meiotic cell cycle
H	0051603	biological_process	proteolysis involved in protein catabolic process
H	0061136	biological_process	regulation of proteasomal protein catabolic process
H	0070062	cellular_component	extracellular exosome
H	0071357	biological_process	cellular response to type I interferon
H	0072539	biological_process	T-helper 17 cell differentiation
H	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
H	1904813	cellular_component	ficolin-1-rich granule lumen
H	1990111	cellular_component	spermatoproteasome complex
H	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
I	0000502	cellular_component	proteasome complex
I	0000932	cellular_component	P-body
I	0002376	biological_process	immune system process
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005839	cellular_component	proteasome core complex
I	0006281	biological_process	DNA repair
I	0006511	biological_process	ubiquitin-dependent protein catabolic process
I	0006915	biological_process	apoptotic process
I	0006974	biological_process	DNA damage response
I	0006979	biological_process	response to oxidative stress
I	0007283	biological_process	spermatogenesis
I	0008021	cellular_component	synaptic vesicle
I	0010498	biological_process	proteasomal protein catabolic process
I	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
I	0019773	cellular_component	proteasome core complex, alpha-subunit complex
I	0030317	biological_process	flagellated sperm motility
I	0032729	biological_process	positive regulation of type II interferon production
I	0032743	biological_process	positive regulation of interleukin-2 production
I	0032760	biological_process	positive regulation of tumor necrosis factor production
I	0034341	biological_process	response to type II interferon
I	0034515	cellular_component	proteasome storage granule
I	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
I	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
I	0045061	biological_process	thymic T cell selection
I	0045063	biological_process	T-helper 1 cell differentiation
I	0045590	biological_process	negative regulation of regulatory T cell differentiation
I	0051321	biological_process	meiotic cell cycle
I	0051603	biological_process	proteolysis involved in protein catabolic process
I	0061136	biological_process	regulation of proteasomal protein catabolic process
I	0070062	cellular_component	extracellular exosome
I	0071357	biological_process	cellular response to type I interferon
I	0072539	biological_process	T-helper 17 cell differentiation
I	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
I	1990111	cellular_component	spermatoproteasome complex
I	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
J	0000502	cellular_component	proteasome complex
J	0002376	biological_process	immune system process
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005839	cellular_component	proteasome core complex
J	0006281	biological_process	DNA repair
J	0006511	biological_process	ubiquitin-dependent protein catabolic process
J	0006915	biological_process	apoptotic process
J	0006974	biological_process	DNA damage response
J	0006979	biological_process	response to oxidative stress
J	0008021	cellular_component	synaptic vesicle
J	0010498	biological_process	proteasomal protein catabolic process
J	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
J	0019773	cellular_component	proteasome core complex, alpha-subunit complex
J	0030317	biological_process	flagellated sperm motility
J	0032729	biological_process	positive regulation of type II interferon production
J	0032743	biological_process	positive regulation of interleukin-2 production
J	0032760	biological_process	positive regulation of tumor necrosis factor production
J	0034341	biological_process	response to type II interferon
J	0034515	cellular_component	proteasome storage granule
J	0042802	molecular_function	identical protein binding
J	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
J	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
J	0045061	biological_process	thymic T cell selection
J	0045063	biological_process	T-helper 1 cell differentiation
J	0045590	biological_process	negative regulation of regulatory T cell differentiation
J	0051603	biological_process	proteolysis involved in protein catabolic process
J	0061136	biological_process	regulation of proteasomal protein catabolic process
J	0070062	cellular_component	extracellular exosome
J	0071357	biological_process	cellular response to type I interferon
J	0072539	biological_process	T-helper 17 cell differentiation
J	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
J	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
K	0000502	cellular_component	proteasome complex
K	0002376	biological_process	immune system process
K	0005515	molecular_function	protein binding
K	0005576	cellular_component	extracellular region
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005839	cellular_component	proteasome core complex
K	0006281	biological_process	DNA repair
K	0006511	biological_process	ubiquitin-dependent protein catabolic process
K	0006915	biological_process	apoptotic process
K	0006974	biological_process	DNA damage response
K	0006979	biological_process	response to oxidative stress
K	0007283	biological_process	spermatogenesis
K	0008021	cellular_component	synaptic vesicle
K	0010498	biological_process	proteasomal protein catabolic process
K	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
K	0019773	cellular_component	proteasome core complex, alpha-subunit complex
K	0030317	biological_process	flagellated sperm motility
K	0032729	biological_process	positive regulation of type II interferon production
K	0032743	biological_process	positive regulation of interleukin-2 production
K	0032760	biological_process	positive regulation of tumor necrosis factor production
K	0034341	biological_process	response to type II interferon
K	0034515	cellular_component	proteasome storage granule
K	0034774	cellular_component	secretory granule lumen
K	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
K	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
K	0045061	biological_process	thymic T cell selection
K	0045063	biological_process	T-helper 1 cell differentiation
K	0045590	biological_process	negative regulation of regulatory T cell differentiation
K	0051321	biological_process	meiotic cell cycle
K	0051603	biological_process	proteolysis involved in protein catabolic process
K	0061136	biological_process	regulation of proteasomal protein catabolic process
K	0070062	cellular_component	extracellular exosome
K	0071357	biological_process	cellular response to type I interferon
K	0072539	biological_process	T-helper 17 cell differentiation
K	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
K	1904813	cellular_component	ficolin-1-rich granule lumen
K	1990111	cellular_component	spermatoproteasome complex
K	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
L	0000502	cellular_component	proteasome complex
L	0001530	molecular_function	lipopolysaccharide binding
L	0002376	biological_process	immune system process
L	0002862	biological_process	negative regulation of inflammatory response to antigenic stimulus
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005839	cellular_component	proteasome core complex
L	0006281	biological_process	DNA repair
L	0006511	biological_process	ubiquitin-dependent protein catabolic process
L	0006915	biological_process	apoptotic process
L	0006974	biological_process	DNA damage response
L	0006979	biological_process	response to oxidative stress
L	0007283	biological_process	spermatogenesis
L	0008021	cellular_component	synaptic vesicle
L	0010498	biological_process	proteasomal protein catabolic process
L	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
L	0016604	cellular_component	nuclear body
L	0019773	cellular_component	proteasome core complex, alpha-subunit complex
L	0030317	biological_process	flagellated sperm motility
L	0032729	biological_process	positive regulation of type II interferon production
L	0032743	biological_process	positive regulation of interleukin-2 production
L	0032760	biological_process	positive regulation of tumor necrosis factor production
L	0034341	biological_process	response to type II interferon
L	0034515	cellular_component	proteasome storage granule
L	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
L	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
L	0045061	biological_process	thymic T cell selection
L	0045063	biological_process	T-helper 1 cell differentiation
L	0045590	biological_process	negative regulation of regulatory T cell differentiation
L	0051321	biological_process	meiotic cell cycle
L	0051603	biological_process	proteolysis involved in protein catabolic process
L	0061136	biological_process	regulation of proteasomal protein catabolic process
L	0070062	cellular_component	extracellular exosome
L	0071357	biological_process	cellular response to type I interferon
L	0072539	biological_process	T-helper 17 cell differentiation
L	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
L	1990111	cellular_component	spermatoproteasome complex
L	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
M	0000502	cellular_component	proteasome complex
M	0002376	biological_process	immune system process
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005839	cellular_component	proteasome core complex
M	0006281	biological_process	DNA repair
M	0006511	biological_process	ubiquitin-dependent protein catabolic process
M	0006915	biological_process	apoptotic process
M	0006974	biological_process	DNA damage response
M	0006979	biological_process	response to oxidative stress
M	0007283	biological_process	spermatogenesis
M	0008021	cellular_component	synaptic vesicle
M	0010498	biological_process	proteasomal protein catabolic process
M	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
M	0019773	cellular_component	proteasome core complex, alpha-subunit complex
M	0030317	biological_process	flagellated sperm motility
M	0031625	molecular_function	ubiquitin protein ligase binding
M	0032729	biological_process	positive regulation of type II interferon production
M	0032743	biological_process	positive regulation of interleukin-2 production
M	0032760	biological_process	positive regulation of tumor necrosis factor production
M	0034341	biological_process	response to type II interferon
M	0034515	cellular_component	proteasome storage granule
M	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
M	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
M	0045061	biological_process	thymic T cell selection
M	0045063	biological_process	T-helper 1 cell differentiation
M	0045590	biological_process	negative regulation of regulatory T cell differentiation
M	0051321	biological_process	meiotic cell cycle
M	0051603	biological_process	proteolysis involved in protein catabolic process
M	0061136	biological_process	regulation of proteasomal protein catabolic process
M	0070062	cellular_component	extracellular exosome
M	0071357	biological_process	cellular response to type I interferon
M	0072539	biological_process	T-helper 17 cell differentiation
M	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
M	1990111	cellular_component	spermatoproteasome complex
M	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
N	0000502	cellular_component	proteasome complex
N	0004175	molecular_function	endopeptidase activity
N	0004298	molecular_function	threonine-type endopeptidase activity
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0005839	cellular_component	proteasome core complex
N	0006281	biological_process	DNA repair
N	0006508	biological_process	proteolysis
N	0006915	biological_process	apoptotic process
N	0006974	biological_process	DNA damage response
N	0006979	biological_process	response to oxidative stress
N	0007283	biological_process	spermatogenesis
N	0008021	cellular_component	synaptic vesicle
N	0008233	molecular_function	peptidase activity
N	0010498	biological_process	proteasomal protein catabolic process
N	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
N	0016787	molecular_function	hydrolase activity
N	0019774	cellular_component	proteasome core complex, beta-subunit complex
N	0030317	biological_process	flagellated sperm motility
N	0034515	cellular_component	proteasome storage granule
N	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
N	0045296	molecular_function	cadherin binding
N	0051321	biological_process	meiotic cell cycle
N	0051603	biological_process	proteolysis involved in protein catabolic process
N	0061136	biological_process	regulation of proteasomal protein catabolic process
N	0070062	cellular_component	extracellular exosome
N	0071357	biological_process	cellular response to type I interferon
N	1990111	cellular_component	spermatoproteasome complex
N	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
O	0000502	cellular_component	proteasome complex
O	0004175	molecular_function	endopeptidase activity
O	0004298	molecular_function	threonine-type endopeptidase activity
O	0005515	molecular_function	protein binding
O	0005576	cellular_component	extracellular region
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005839	cellular_component	proteasome core complex
O	0006281	biological_process	DNA repair
O	0006508	biological_process	proteolysis
O	0006915	biological_process	apoptotic process
O	0006974	biological_process	DNA damage response
O	0006979	biological_process	response to oxidative stress
O	0007283	biological_process	spermatogenesis
O	0008021	cellular_component	synaptic vesicle
O	0008233	molecular_function	peptidase activity
O	0010498	biological_process	proteasomal protein catabolic process
O	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
O	0016604	cellular_component	nuclear body
O	0016787	molecular_function	hydrolase activity
O	0019774	cellular_component	proteasome core complex, beta-subunit complex
O	0030317	biological_process	flagellated sperm motility
O	0034515	cellular_component	proteasome storage granule
O	0034774	cellular_component	secretory granule lumen
O	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
O	0051321	biological_process	meiotic cell cycle
O	0051603	biological_process	proteolysis involved in protein catabolic process
O	0061136	biological_process	regulation of proteasomal protein catabolic process
O	0071357	biological_process	cellular response to type I interferon
O	1904813	cellular_component	ficolin-1-rich granule lumen
O	1990111	cellular_component	spermatoproteasome complex
O	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
P	0000502	cellular_component	proteasome complex
P	0002376	biological_process	immune system process
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005839	cellular_component	proteasome core complex
P	0006281	biological_process	DNA repair
P	0006915	biological_process	apoptotic process
P	0006974	biological_process	DNA damage response
P	0006979	biological_process	response to oxidative stress
P	0007283	biological_process	spermatogenesis
P	0008021	cellular_component	synaptic vesicle
P	0010498	biological_process	proteasomal protein catabolic process
P	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
P	0019774	cellular_component	proteasome core complex, beta-subunit complex
P	0030317	biological_process	flagellated sperm motility
P	0032729	biological_process	positive regulation of type II interferon production
P	0032743	biological_process	positive regulation of interleukin-2 production
P	0032760	biological_process	positive regulation of tumor necrosis factor production
P	0034341	biological_process	response to type II interferon
P	0034515	cellular_component	proteasome storage granule
P	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
P	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
P	0045061	biological_process	thymic T cell selection
P	0045063	biological_process	T-helper 1 cell differentiation
P	0045590	biological_process	negative regulation of regulatory T cell differentiation
P	0051321	biological_process	meiotic cell cycle
P	0051603	biological_process	proteolysis involved in protein catabolic process
P	0061136	biological_process	regulation of proteasomal protein catabolic process
P	0070062	cellular_component	extracellular exosome
P	0071357	biological_process	cellular response to type I interferon
P	0072539	biological_process	T-helper 17 cell differentiation
P	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
P	1990111	cellular_component	spermatoproteasome complex
P	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
Q	0000502	cellular_component	proteasome complex
Q	0002376	biological_process	immune system process
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0005839	cellular_component	proteasome core complex
Q	0006281	biological_process	DNA repair
Q	0006915	biological_process	apoptotic process
Q	0006974	biological_process	DNA damage response
Q	0006979	biological_process	response to oxidative stress
Q	0007283	biological_process	spermatogenesis
Q	0008021	cellular_component	synaptic vesicle
Q	0010498	biological_process	proteasomal protein catabolic process
Q	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
Q	0016020	cellular_component	membrane
Q	0019774	cellular_component	proteasome core complex, beta-subunit complex
Q	0030317	biological_process	flagellated sperm motility
Q	0032729	biological_process	positive regulation of type II interferon production
Q	0032743	biological_process	positive regulation of interleukin-2 production
Q	0032760	biological_process	positive regulation of tumor necrosis factor production
Q	0034341	biological_process	response to type II interferon
Q	0034515	cellular_component	proteasome storage granule
Q	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Q	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
Q	0045061	biological_process	thymic T cell selection
Q	0045063	biological_process	T-helper 1 cell differentiation
Q	0045590	biological_process	negative regulation of regulatory T cell differentiation
Q	0051321	biological_process	meiotic cell cycle
Q	0051603	biological_process	proteolysis involved in protein catabolic process
Q	0061136	biological_process	regulation of proteasomal protein catabolic process
Q	0070062	cellular_component	extracellular exosome
Q	0071357	biological_process	cellular response to type I interferon
Q	0072539	biological_process	T-helper 17 cell differentiation
Q	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
Q	1990111	cellular_component	spermatoproteasome complex
Q	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
R	0000502	cellular_component	proteasome complex
R	0004175	molecular_function	endopeptidase activity
R	0004298	molecular_function	threonine-type endopeptidase activity
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0005839	cellular_component	proteasome core complex
R	0006281	biological_process	DNA repair
R	0006508	biological_process	proteolysis
R	0006915	biological_process	apoptotic process
R	0006974	biological_process	DNA damage response
R	0006979	biological_process	response to oxidative stress
R	0007283	biological_process	spermatogenesis
R	0008021	cellular_component	synaptic vesicle
R	0008233	molecular_function	peptidase activity
R	0010498	biological_process	proteasomal protein catabolic process
R	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
R	0016787	molecular_function	hydrolase activity
R	0019774	cellular_component	proteasome core complex, beta-subunit complex
R	0030317	biological_process	flagellated sperm motility
R	0034515	cellular_component	proteasome storage granule
R	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
R	0043248	biological_process	proteasome assembly
R	0051321	biological_process	meiotic cell cycle
R	0051603	biological_process	proteolysis involved in protein catabolic process
R	0061136	biological_process	regulation of proteasomal protein catabolic process
R	0070062	cellular_component	extracellular exosome
R	0071357	biological_process	cellular response to type I interferon
R	1990111	cellular_component	spermatoproteasome complex
R	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
S	0000502	cellular_component	proteasome complex
S	0002376	biological_process	immune system process
S	0005515	molecular_function	protein binding
S	0005576	cellular_component	extracellular region
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005839	cellular_component	proteasome core complex
S	0006281	biological_process	DNA repair
S	0006915	biological_process	apoptotic process
S	0006974	biological_process	DNA damage response
S	0006979	biological_process	response to oxidative stress
S	0007283	biological_process	spermatogenesis
S	0008021	cellular_component	synaptic vesicle
S	0010498	biological_process	proteasomal protein catabolic process
S	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
S	0019774	cellular_component	proteasome core complex, beta-subunit complex
S	0030317	biological_process	flagellated sperm motility
S	0032729	biological_process	positive regulation of type II interferon production
S	0032743	biological_process	positive regulation of interleukin-2 production
S	0032760	biological_process	positive regulation of tumor necrosis factor production
S	0034341	biological_process	response to type II interferon
S	0034515	cellular_component	proteasome storage granule
S	0034774	cellular_component	secretory granule lumen
S	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
S	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
S	0045061	biological_process	thymic T cell selection
S	0045063	biological_process	T-helper 1 cell differentiation
S	0045590	biological_process	negative regulation of regulatory T cell differentiation
S	0051321	biological_process	meiotic cell cycle
S	0051603	biological_process	proteolysis involved in protein catabolic process
S	0061136	biological_process	regulation of proteasomal protein catabolic process
S	0070062	cellular_component	extracellular exosome
S	0071357	biological_process	cellular response to type I interferon
S	0072539	biological_process	T-helper 17 cell differentiation
S	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
S	1904813	cellular_component	ficolin-1-rich granule lumen
S	1990111	cellular_component	spermatoproteasome complex
S	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
T	0000502	cellular_component	proteasome complex
T	0001530	molecular_function	lipopolysaccharide binding
T	0002376	biological_process	immune system process
T	0002862	biological_process	negative regulation of inflammatory response to antigenic stimulus
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0005839	cellular_component	proteasome core complex
T	0006281	biological_process	DNA repair
T	0006915	biological_process	apoptotic process
T	0006974	biological_process	DNA damage response
T	0006979	biological_process	response to oxidative stress
T	0007283	biological_process	spermatogenesis
T	0008021	cellular_component	synaptic vesicle
T	0010498	biological_process	proteasomal protein catabolic process
T	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
T	0019774	cellular_component	proteasome core complex, beta-subunit complex
T	0030317	biological_process	flagellated sperm motility
T	0032729	biological_process	positive regulation of type II interferon production
T	0032743	biological_process	positive regulation of interleukin-2 production
T	0032760	biological_process	positive regulation of tumor necrosis factor production
T	0034341	biological_process	response to type II interferon
T	0034515	cellular_component	proteasome storage granule
T	0036064	cellular_component	ciliary basal body
T	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
T	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
T	0045061	biological_process	thymic T cell selection
T	0045063	biological_process	T-helper 1 cell differentiation
T	0045590	biological_process	negative regulation of regulatory T cell differentiation
T	0051321	biological_process	meiotic cell cycle
T	0051603	biological_process	proteolysis involved in protein catabolic process
T	0061136	biological_process	regulation of proteasomal protein catabolic process
T	0070062	cellular_component	extracellular exosome
T	0071357	biological_process	cellular response to type I interferon
T	0072539	biological_process	T-helper 17 cell differentiation
T	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
T	1990111	cellular_component	spermatoproteasome complex
T	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
U	0000502	cellular_component	proteasome complex
U	0005515	molecular_function	protein binding
U	0005576	cellular_component	extracellular region
U	0005634	cellular_component	nucleus
U	0005654	cellular_component	nucleoplasm
U	0005829	cellular_component	cytosol
U	0005838	cellular_component	proteasome regulatory particle
U	0006979	biological_process	response to oxidative stress
U	0008021	cellular_component	synaptic vesicle
U	0008540	cellular_component	proteasome regulatory particle, base subcomplex
U	0010498	biological_process	proteasomal protein catabolic process
U	0016020	cellular_component	membrane
U	0022624	cellular_component	proteasome accessory complex
U	0030234	molecular_function	enzyme regulator activity
U	0031625	molecular_function	ubiquitin protein ligase binding
U	0034515	cellular_component	proteasome storage granule
U	0035578	cellular_component	azurophil granule lumen
U	0042176	biological_process	regulation of protein catabolic process
U	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
U	0061136	biological_process	regulation of proteasomal protein catabolic process
U	0071357	biological_process	cellular response to type I interferon
U	2000311	biological_process	regulation of AMPA receptor activity
V	0000502	cellular_component	proteasome complex
V	0005515	molecular_function	protein binding
V	0005576	cellular_component	extracellular region
V	0005634	cellular_component	nucleus
V	0005654	cellular_component	nucleoplasm
V	0005829	cellular_component	cytosol
V	0005838	cellular_component	proteasome regulatory particle
V	0006511	biological_process	ubiquitin-dependent protein catabolic process
V	0006979	biological_process	response to oxidative stress
V	0008021	cellular_component	synaptic vesicle
V	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
V	0010498	biological_process	proteasomal protein catabolic process
V	0016020	cellular_component	membrane
V	0022624	cellular_component	proteasome accessory complex
V	0030234	molecular_function	enzyme regulator activity
V	0034774	cellular_component	secretory granule lumen
V	0042176	biological_process	regulation of protein catabolic process
V	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
V	0061136	biological_process	regulation of proteasomal protein catabolic process
V	0070062	cellular_component	extracellular exosome
V	0071357	biological_process	cellular response to type I interferon
V	1904813	cellular_component	ficolin-1-rich granule lumen
V	2000311	biological_process	regulation of AMPA receptor activity
W	0000502	cellular_component	proteasome complex
W	0005515	molecular_function	protein binding
W	0005576	cellular_component	extracellular region
W	0005654	cellular_component	nucleoplasm
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0005838	cellular_component	proteasome regulatory particle
W	0006979	biological_process	response to oxidative stress
W	0008021	cellular_component	synaptic vesicle
W	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
W	0010498	biological_process	proteasomal protein catabolic process
W	0016020	cellular_component	membrane
W	0022624	cellular_component	proteasome accessory complex
W	0034774	cellular_component	secretory granule lumen
W	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
W	0061136	biological_process	regulation of proteasomal protein catabolic process
W	0070062	cellular_component	extracellular exosome
W	0071357	biological_process	cellular response to type I interferon
W	1904813	cellular_component	ficolin-1-rich granule lumen
W	2000311	biological_process	regulation of AMPA receptor activity
X	0000502	cellular_component	proteasome complex
X	0005198	molecular_function	structural molecule activity
X	0005515	molecular_function	protein binding
X	0005576	cellular_component	extracellular region
X	0005634	cellular_component	nucleus
X	0005654	cellular_component	nucleoplasm
X	0005829	cellular_component	cytosol
X	0005838	cellular_component	proteasome regulatory particle
X	0006511	biological_process	ubiquitin-dependent protein catabolic process
X	0006979	biological_process	response to oxidative stress
X	0008021	cellular_component	synaptic vesicle
X	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
X	0010498	biological_process	proteasomal protein catabolic process
X	0016020	cellular_component	membrane
X	0022624	cellular_component	proteasome accessory complex
X	0032991	cellular_component	protein-containing complex
X	0034774	cellular_component	secretory granule lumen
X	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
X	0043248	biological_process	proteasome assembly
X	0048863	biological_process	stem cell differentiation
X	0061136	biological_process	regulation of proteasomal protein catabolic process
X	0071357	biological_process	cellular response to type I interferon
X	1904813	cellular_component	ficolin-1-rich granule lumen
X	2000311	biological_process	regulation of AMPA receptor activity
Y	0000502	cellular_component	proteasome complex
Y	0005515	molecular_function	protein binding
Y	0005576	cellular_component	extracellular region
Y	0005654	cellular_component	nucleoplasm
Y	0005829	cellular_component	cytosol
Y	0005838	cellular_component	proteasome regulatory particle
Y	0006979	biological_process	response to oxidative stress
Y	0008021	cellular_component	synaptic vesicle
Y	0010498	biological_process	proteasomal protein catabolic process
Y	0022624	cellular_component	proteasome accessory complex
Y	0032991	cellular_component	protein-containing complex
Y	0034774	cellular_component	secretory granule lumen
Y	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Y	0061136	biological_process	regulation of proteasomal protein catabolic process
Y	0071357	biological_process	cellular response to type I interferon
Y	1904813	cellular_component	ficolin-1-rich granule lumen
Y	2000311	biological_process	regulation of AMPA receptor activity
Z	0000502	cellular_component	proteasome complex
Z	0005515	molecular_function	protein binding
Z	0005576	cellular_component	extracellular region
Z	0005634	cellular_component	nucleus
Z	0005654	cellular_component	nucleoplasm
Z	0005829	cellular_component	cytosol
Z	0005838	cellular_component	proteasome regulatory particle
Z	0006979	biological_process	response to oxidative stress
Z	0008021	cellular_component	synaptic vesicle
Z	0008233	molecular_function	peptidase activity
Z	0008237	molecular_function	metallopeptidase activity
Z	0010498	biological_process	proteasomal protein catabolic process
Z	0016020	cellular_component	membrane
Z	0022624	cellular_component	proteasome accessory complex
Z	0034774	cellular_component	secretory granule lumen
Z	0042803	molecular_function	protein homodimerization activity
Z	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Z	0061136	biological_process	regulation of proteasomal protein catabolic process
Z	0070062	cellular_component	extracellular exosome
Z	0071357	biological_process	cellular response to type I interferon
Z	0140492	molecular_function	metal-dependent deubiquitinase activity
Z	1904813	cellular_component	ficolin-1-rich granule lumen
Z	2000311	biological_process	regulation of AMPA receptor activity
a	0000502	cellular_component	proteasome complex
a	0005198	molecular_function	structural molecule activity
a	0005515	molecular_function	protein binding
a	0005576	cellular_component	extracellular region
a	0005634	cellular_component	nucleus
a	0005654	cellular_component	nucleoplasm
a	0005829	cellular_component	cytosol
a	0005838	cellular_component	proteasome regulatory particle
a	0006511	biological_process	ubiquitin-dependent protein catabolic process
a	0006979	biological_process	response to oxidative stress
a	0008021	cellular_component	synaptic vesicle
a	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
a	0010498	biological_process	proteasomal protein catabolic process
a	0016020	cellular_component	membrane
a	0022624	cellular_component	proteasome accessory complex
a	0034774	cellular_component	secretory granule lumen
a	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
a	0061136	biological_process	regulation of proteasomal protein catabolic process
a	0071357	biological_process	cellular response to type I interferon
a	1904813	cellular_component	ficolin-1-rich granule lumen
a	2000311	biological_process	regulation of AMPA receptor activity
b	0000502	cellular_component	proteasome complex
b	0003723	molecular_function	RNA binding
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0005829	cellular_component	cytosol
b	0006979	biological_process	response to oxidative stress
b	0008021	cellular_component	synaptic vesicle
b	0008540	cellular_component	proteasome regulatory particle, base subcomplex
b	0010498	biological_process	proteasomal protein catabolic process
b	0022624	cellular_component	proteasome accessory complex
b	0031593	molecular_function	polyubiquitin modification-dependent protein binding
b	0042802	molecular_function	identical protein binding
b	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
b	0060090	molecular_function	molecular adaptor activity
b	0061136	biological_process	regulation of proteasomal protein catabolic process
b	0071357	biological_process	cellular response to type I interferon
b	2000311	biological_process	regulation of AMPA receptor activity
c	0000502	cellular_component	proteasome complex
c	0000724	biological_process	double-strand break repair via homologous recombination
c	0004843	molecular_function	cysteine-type deubiquitinase activity
c	0005515	molecular_function	protein binding
c	0005576	cellular_component	extracellular region
c	0005634	cellular_component	nucleus
c	0005654	cellular_component	nucleoplasm
c	0005829	cellular_component	cytosol
c	0006281	biological_process	DNA repair
c	0006303	biological_process	double-strand break repair via nonhomologous end joining
c	0006508	biological_process	proteolysis
c	0006511	biological_process	ubiquitin-dependent protein catabolic process
c	0006890	biological_process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
c	0006974	biological_process	DNA damage response
c	0006979	biological_process	response to oxidative stress
c	0008021	cellular_component	synaptic vesicle
c	0008233	molecular_function	peptidase activity
c	0008237	molecular_function	metallopeptidase activity
c	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
c	0010498	biological_process	proteasomal protein catabolic process
c	0016241	biological_process	regulation of macroautophagy
c	0016579	biological_process	protein deubiquitination
c	0016787	molecular_function	hydrolase activity
c	0022624	cellular_component	proteasome accessory complex
c	0034774	cellular_component	secretory granule lumen
c	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
c	0046872	molecular_function	metal ion binding
c	0061133	molecular_function	endopeptidase activator activity
c	0061136	biological_process	regulation of proteasomal protein catabolic process
c	0061578	molecular_function	K63-linked deubiquitinase activity
c	0070536	biological_process	protein K63-linked deubiquitination
c	0070628	molecular_function	proteasome binding
c	0071357	biological_process	cellular response to type I interferon
c	0140492	molecular_function	metal-dependent deubiquitinase activity
c	1904813	cellular_component	ficolin-1-rich granule lumen
c	2000311	biological_process	regulation of AMPA receptor activity
d	0000502	cellular_component	proteasome complex
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005654	cellular_component	nucleoplasm
d	0005829	cellular_component	cytosol
d	0005838	cellular_component	proteasome regulatory particle
d	0006508	biological_process	proteolysis
d	0006979	biological_process	response to oxidative stress
d	0008021	cellular_component	synaptic vesicle
d	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
d	0010498	biological_process	proteasomal protein catabolic process
d	0022624	cellular_component	proteasome accessory complex
d	0032991	cellular_component	protein-containing complex
d	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
d	0061136	biological_process	regulation of proteasomal protein catabolic process
d	0071357	biological_process	cellular response to type I interferon
d	2000311	biological_process	regulation of AMPA receptor activity
e	0000502	cellular_component	proteasome complex
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005654	cellular_component	nucleoplasm
e	0005829	cellular_component	cytosol
e	0006406	biological_process	mRNA export from nucleus
e	0006979	biological_process	response to oxidative stress
e	0008021	cellular_component	synaptic vesicle
e	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
e	0010498	biological_process	proteasomal protein catabolic process
e	0022624	cellular_component	proteasome accessory complex
e	0032039	cellular_component	integrator complex
e	0032991	cellular_component	protein-containing complex
e	0043130	molecular_function	ubiquitin binding
e	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
e	0043248	biological_process	proteasome assembly
e	0045944	biological_process	positive regulation of transcription by RNA polymerase II
e	0061136	biological_process	regulation of proteasomal protein catabolic process
e	0070390	cellular_component	transcription export complex 2
e	0071357	biological_process	cellular response to type I interferon
e	2000311	biological_process	regulation of AMPA receptor activity
f	0000502	cellular_component	proteasome complex
f	0005515	molecular_function	protein binding
f	0005576	cellular_component	extracellular region
f	0005634	cellular_component	nucleus
f	0005654	cellular_component	nucleoplasm
f	0005829	cellular_component	cytosol
f	0005838	cellular_component	proteasome regulatory particle
f	0006979	biological_process	response to oxidative stress
f	0008021	cellular_component	synaptic vesicle
f	0008540	cellular_component	proteasome regulatory particle, base subcomplex
f	0010498	biological_process	proteasomal protein catabolic process
f	0016020	cellular_component	membrane
f	0022624	cellular_component	proteasome accessory complex
f	0030234	molecular_function	enzyme regulator activity
f	0034515	cellular_component	proteasome storage granule
f	0034774	cellular_component	secretory granule lumen
f	0042176	biological_process	regulation of protein catabolic process
f	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
f	0061136	biological_process	regulation of proteasomal protein catabolic process
f	0070062	cellular_component	extracellular exosome
f	0071357	biological_process	cellular response to type I interferon
f	1904813	cellular_component	ficolin-1-rich granule lumen
f	2000311	biological_process	regulation of AMPA receptor activity
n	0000502	cellular_component	proteasome complex
n	0004175	molecular_function	endopeptidase activity
n	0004298	molecular_function	threonine-type endopeptidase activity
n	0005515	molecular_function	protein binding
n	0005634	cellular_component	nucleus
n	0005654	cellular_component	nucleoplasm
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0005839	cellular_component	proteasome core complex
n	0006281	biological_process	DNA repair
n	0006508	biological_process	proteolysis
n	0006915	biological_process	apoptotic process
n	0006974	biological_process	DNA damage response
n	0006979	biological_process	response to oxidative stress
n	0007283	biological_process	spermatogenesis
n	0008021	cellular_component	synaptic vesicle
n	0008233	molecular_function	peptidase activity
n	0010498	biological_process	proteasomal protein catabolic process
n	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
n	0016787	molecular_function	hydrolase activity
n	0019774	cellular_component	proteasome core complex, beta-subunit complex
n	0030317	biological_process	flagellated sperm motility
n	0034515	cellular_component	proteasome storage granule
n	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
n	0045296	molecular_function	cadherin binding
n	0051321	biological_process	meiotic cell cycle
n	0051603	biological_process	proteolysis involved in protein catabolic process
n	0061136	biological_process	regulation of proteasomal protein catabolic process
n	0070062	cellular_component	extracellular exosome
n	0071357	biological_process	cellular response to type I interferon
n	1990111	cellular_component	spermatoproteasome complex
n	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
o	0000502	cellular_component	proteasome complex
o	0004175	molecular_function	endopeptidase activity
o	0004298	molecular_function	threonine-type endopeptidase activity
o	0005515	molecular_function	protein binding
o	0005576	cellular_component	extracellular region
o	0005634	cellular_component	nucleus
o	0005654	cellular_component	nucleoplasm
o	0005737	cellular_component	cytoplasm
o	0005829	cellular_component	cytosol
o	0005839	cellular_component	proteasome core complex
o	0006281	biological_process	DNA repair
o	0006508	biological_process	proteolysis
o	0006915	biological_process	apoptotic process
o	0006974	biological_process	DNA damage response
o	0006979	biological_process	response to oxidative stress
o	0007283	biological_process	spermatogenesis
o	0008021	cellular_component	synaptic vesicle
o	0008233	molecular_function	peptidase activity
o	0010498	biological_process	proteasomal protein catabolic process
o	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
o	0016604	cellular_component	nuclear body
o	0016787	molecular_function	hydrolase activity
o	0019774	cellular_component	proteasome core complex, beta-subunit complex
o	0030317	biological_process	flagellated sperm motility
o	0034515	cellular_component	proteasome storage granule
o	0034774	cellular_component	secretory granule lumen
o	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
o	0051321	biological_process	meiotic cell cycle
o	0051603	biological_process	proteolysis involved in protein catabolic process
o	0061136	biological_process	regulation of proteasomal protein catabolic process
o	0071357	biological_process	cellular response to type I interferon
o	1904813	cellular_component	ficolin-1-rich granule lumen
o	1990111	cellular_component	spermatoproteasome complex
o	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
p	0000502	cellular_component	proteasome complex
p	0002376	biological_process	immune system process
p	0005515	molecular_function	protein binding
p	0005634	cellular_component	nucleus
p	0005654	cellular_component	nucleoplasm
p	0005737	cellular_component	cytoplasm
p	0005829	cellular_component	cytosol
p	0005839	cellular_component	proteasome core complex
p	0006281	biological_process	DNA repair
p	0006915	biological_process	apoptotic process
p	0006974	biological_process	DNA damage response
p	0006979	biological_process	response to oxidative stress
p	0007283	biological_process	spermatogenesis
p	0008021	cellular_component	synaptic vesicle
p	0010498	biological_process	proteasomal protein catabolic process
p	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
p	0019774	cellular_component	proteasome core complex, beta-subunit complex
p	0030317	biological_process	flagellated sperm motility
p	0032729	biological_process	positive regulation of type II interferon production
p	0032743	biological_process	positive regulation of interleukin-2 production
p	0032760	biological_process	positive regulation of tumor necrosis factor production
p	0034341	biological_process	response to type II interferon
p	0034515	cellular_component	proteasome storage granule
p	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
p	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
p	0045061	biological_process	thymic T cell selection
p	0045063	biological_process	T-helper 1 cell differentiation
p	0045590	biological_process	negative regulation of regulatory T cell differentiation
p	0051321	biological_process	meiotic cell cycle
p	0051603	biological_process	proteolysis involved in protein catabolic process
p	0061136	biological_process	regulation of proteasomal protein catabolic process
p	0070062	cellular_component	extracellular exosome
p	0071357	biological_process	cellular response to type I interferon
p	0072539	biological_process	T-helper 17 cell differentiation
p	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
p	1990111	cellular_component	spermatoproteasome complex
p	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
q	0000502	cellular_component	proteasome complex
q	0002376	biological_process	immune system process
q	0005515	molecular_function	protein binding
q	0005634	cellular_component	nucleus
q	0005654	cellular_component	nucleoplasm
q	0005737	cellular_component	cytoplasm
q	0005829	cellular_component	cytosol
q	0005839	cellular_component	proteasome core complex
q	0006281	biological_process	DNA repair
q	0006915	biological_process	apoptotic process
q	0006974	biological_process	DNA damage response
q	0006979	biological_process	response to oxidative stress
q	0007283	biological_process	spermatogenesis
q	0008021	cellular_component	synaptic vesicle
q	0010498	biological_process	proteasomal protein catabolic process
q	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
q	0016020	cellular_component	membrane
q	0019774	cellular_component	proteasome core complex, beta-subunit complex
q	0030317	biological_process	flagellated sperm motility
q	0032729	biological_process	positive regulation of type II interferon production
q	0032743	biological_process	positive regulation of interleukin-2 production
q	0032760	biological_process	positive regulation of tumor necrosis factor production
q	0034341	biological_process	response to type II interferon
q	0034515	cellular_component	proteasome storage granule
q	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
q	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
q	0045061	biological_process	thymic T cell selection
q	0045063	biological_process	T-helper 1 cell differentiation
q	0045590	biological_process	negative regulation of regulatory T cell differentiation
q	0051321	biological_process	meiotic cell cycle
q	0051603	biological_process	proteolysis involved in protein catabolic process
q	0061136	biological_process	regulation of proteasomal protein catabolic process
q	0070062	cellular_component	extracellular exosome
q	0071357	biological_process	cellular response to type I interferon
q	0072539	biological_process	T-helper 17 cell differentiation
q	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
q	1990111	cellular_component	spermatoproteasome complex
q	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
r	0000502	cellular_component	proteasome complex
r	0004175	molecular_function	endopeptidase activity
r	0004298	molecular_function	threonine-type endopeptidase activity
r	0005515	molecular_function	protein binding
r	0005634	cellular_component	nucleus
r	0005654	cellular_component	nucleoplasm
r	0005737	cellular_component	cytoplasm
r	0005829	cellular_component	cytosol
r	0005839	cellular_component	proteasome core complex
r	0006281	biological_process	DNA repair
r	0006508	biological_process	proteolysis
r	0006915	biological_process	apoptotic process
r	0006974	biological_process	DNA damage response
r	0006979	biological_process	response to oxidative stress
r	0007283	biological_process	spermatogenesis
r	0008021	cellular_component	synaptic vesicle
r	0008233	molecular_function	peptidase activity
r	0010498	biological_process	proteasomal protein catabolic process
r	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
r	0016787	molecular_function	hydrolase activity
r	0019774	cellular_component	proteasome core complex, beta-subunit complex
r	0030317	biological_process	flagellated sperm motility
r	0034515	cellular_component	proteasome storage granule
r	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
r	0043248	biological_process	proteasome assembly
r	0051321	biological_process	meiotic cell cycle
r	0051603	biological_process	proteolysis involved in protein catabolic process
r	0061136	biological_process	regulation of proteasomal protein catabolic process
r	0070062	cellular_component	extracellular exosome
r	0071357	biological_process	cellular response to type I interferon
r	1990111	cellular_component	spermatoproteasome complex
r	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
s	0000502	cellular_component	proteasome complex
s	0002376	biological_process	immune system process
s	0005515	molecular_function	protein binding
s	0005576	cellular_component	extracellular region
s	0005634	cellular_component	nucleus
s	0005654	cellular_component	nucleoplasm
s	0005737	cellular_component	cytoplasm
s	0005829	cellular_component	cytosol
s	0005839	cellular_component	proteasome core complex
s	0006281	biological_process	DNA repair
s	0006915	biological_process	apoptotic process
s	0006974	biological_process	DNA damage response
s	0006979	biological_process	response to oxidative stress
s	0007283	biological_process	spermatogenesis
s	0008021	cellular_component	synaptic vesicle
s	0010498	biological_process	proteasomal protein catabolic process
s	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
s	0019774	cellular_component	proteasome core complex, beta-subunit complex
s	0030317	biological_process	flagellated sperm motility
s	0032729	biological_process	positive regulation of type II interferon production
s	0032743	biological_process	positive regulation of interleukin-2 production
s	0032760	biological_process	positive regulation of tumor necrosis factor production
s	0034341	biological_process	response to type II interferon
s	0034515	cellular_component	proteasome storage granule
s	0034774	cellular_component	secretory granule lumen
s	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
s	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
s	0045061	biological_process	thymic T cell selection
s	0045063	biological_process	T-helper 1 cell differentiation
s	0045590	biological_process	negative regulation of regulatory T cell differentiation
s	0051321	biological_process	meiotic cell cycle
s	0051603	biological_process	proteolysis involved in protein catabolic process
s	0061136	biological_process	regulation of proteasomal protein catabolic process
s	0070062	cellular_component	extracellular exosome
s	0071357	biological_process	cellular response to type I interferon
s	0072539	biological_process	T-helper 17 cell differentiation
s	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
s	1904813	cellular_component	ficolin-1-rich granule lumen
s	1990111	cellular_component	spermatoproteasome complex
s	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
t	0000502	cellular_component	proteasome complex
t	0001530	molecular_function	lipopolysaccharide binding
t	0002376	biological_process	immune system process
t	0002862	biological_process	negative regulation of inflammatory response to antigenic stimulus
t	0005515	molecular_function	protein binding
t	0005634	cellular_component	nucleus
t	0005654	cellular_component	nucleoplasm
t	0005737	cellular_component	cytoplasm
t	0005829	cellular_component	cytosol
t	0005839	cellular_component	proteasome core complex
t	0006281	biological_process	DNA repair
t	0006915	biological_process	apoptotic process
t	0006974	biological_process	DNA damage response
t	0006979	biological_process	response to oxidative stress
t	0007283	biological_process	spermatogenesis
t	0008021	cellular_component	synaptic vesicle
t	0010498	biological_process	proteasomal protein catabolic process
t	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
t	0019774	cellular_component	proteasome core complex, beta-subunit complex
t	0030317	biological_process	flagellated sperm motility
t	0032729	biological_process	positive regulation of type II interferon production
t	0032743	biological_process	positive regulation of interleukin-2 production
t	0032760	biological_process	positive regulation of tumor necrosis factor production
t	0034341	biological_process	response to type II interferon
t	0034515	cellular_component	proteasome storage granule
t	0036064	cellular_component	ciliary basal body
t	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
t	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
t	0045061	biological_process	thymic T cell selection
t	0045063	biological_process	T-helper 1 cell differentiation
t	0045590	biological_process	negative regulation of regulatory T cell differentiation
t	0051321	biological_process	meiotic cell cycle
t	0051603	biological_process	proteolysis involved in protein catabolic process
t	0061136	biological_process	regulation of proteasomal protein catabolic process
t	0070062	cellular_component	extracellular exosome
t	0071357	biological_process	cellular response to type I interferon
t	0072539	biological_process	T-helper 17 cell differentiation
t	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
t	1990111	cellular_component	spermatoproteasome complex
t	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
y	0005515	molecular_function	protein binding
y	0005634	cellular_component	nucleus
y	0005730	cellular_component	nucleolus
y	0005737	cellular_component	cytoplasm
y	0005829	cellular_component	cytosol
y	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
y	0019900	molecular_function	kinase binding
y	0033132	biological_process	negative regulation of glucokinase activity
y	0046676	biological_process	negative regulation of insulin secretion
y	0060090	molecular_function	molecular adaptor activity

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. AAGFSSSGPAATSGAV

Chain	Residue	Details
d	ALA72-VAL87

---

site_id	PS00388
Number of Residues	23
Details	PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YdrgvNtFSPeGRlfQVEYAieA

Chain	Residue	Details
K	TYR8-ALA30
G	PHE9-ALA31
H	TYR6-ALA28
M	TYR8-ALA30
J	TYR3-ALA25
I	TYR5-ALA27
L	TYR6-ALA28

---

site_id	PS00674
Number of Residues	19
Details	AAA AAA-protein family signature. IkVLmATNrpdtLDpALm.R

Chain	Residue	Details
A	ILE315-ARG333
E	VAL273-ARG291
D	VAL305-ARG323
F	VAL326-ARG344
C	ILE289-ARG307
B	VAL325-ARG343

---

site_id	PS00854
Number of Residues	48
Details	PROTEASOME_BETA_1 Proteasome beta-type subunits signature. MAMkGknCVAIAADrrfgiqaqmvttdfq.KifpmgdrlyiglaGlaTD

Chain	Residue	Details
P	MET12-ASP59
R	LEU63-ASP110
o	ALA47-ASP94
S	LEU41-ASP88
n	MET38-ASP85
Q	ILE5-ASP52
T	LEU57-ASP104
I	LEU35-ASP82

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	69
Details	Repeat: {"description":"PC 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	68
Details	Repeat: {"description":"PC 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	68
Details	Repeat: {"description":"PC 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	62
Details	Repeat: {"description":"PC 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	66
Details	Repeat: {"description":"PC 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	47
Details	Repeat: {"description":"PC 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	34
Details	Repeat: {"description":"PC 8"}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	40
Details	Repeat: {"description":"PC 9"}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	32
Details	Repeat: {"description":"PC 10"}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q3TXS7","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	5
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	22
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	682
Details	Domain: {"description":"PCI","evidences":[{"source":"PROSITE-ProRule","id":"PRU01185","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	25
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25218447","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25772364","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2004","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Potts A.","Brablan J.","Quadroni M."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17323924","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25772364","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	270
Details	Domain: {"description":"MPN","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	5
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)"}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	183
Details	Domain: {"description":"VWFA","evidences":[{"source":"PROSITE-ProRule","id":"PRU00219","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	13
Details	Motif: {"description":"JAMM motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17693683","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17323924","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	35
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15144186","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"17370265","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	220
Details	Region: {"description":"May mediate interaction with PRPF9","evidences":[{"source":"UniProtKB","id":"P62196","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q9QUM9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P49722","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	3
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P17220","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine; by ABL1 and ABL2","evidences":[{"source":"PubMed","id":"16678104","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI42
Number of Residues	6
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI43
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"16964243","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI44
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI45
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI46
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; alternate","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI47
Number of Residues	1
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine; alternate","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI48
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17323924","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI49
Number of Residues	6
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"25599644","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27493187","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI50
Number of Residues	2
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","von Kriegsheim A.F.","Kolch W."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI51
Number of Residues	2
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI52
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18502982","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18565852","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19426847","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI53
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"O09061","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI54
Number of Residues	33
Details	Repeat: {"description":"PC 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI55
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"17323924","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI56
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q8VDM4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---