9BJA
C. difficile Tcdb cysteine protease domain in complex with IP6
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: For protease activity => ECO:0000255|PROSITE-ProRule:PRU01107, ECO:0000269|PubMed:27571750 |
| Chain | Residue | Details |
| A | HIS110 | |
| B | HIS110 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile; for protease activity => ECO:0000255|PROSITE-ProRule:PRU01107, ECO:0000269|PubMed:27571750 |
| Chain | Residue | Details |
| A | CYS155 | |
| B | CYS155 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P16154 |
| Chain | Residue | Details |
| A | GLU2 | |
| B | LYS57 | |
| B | LYS104 | |
| B | LYS221 | |
| B | LYS232 | |
| B | LYS249 | |
| A | TYR34 | |
| A | LYS57 | |
| A | LYS104 | |
| A | LYS221 | |
| A | LYS232 | |
| A | LYS249 | |
| B | GLU2 | |
| B | TYR34 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31308519, ECO:0007744|PDB:6OQ5 |
| Chain | Residue | Details |
| A | ASP3 | |
| A | HIS110 | |
| B | ASP3 | |
| B | HIS110 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31308519, ECO:0000305|PubMed:27571750, ECO:0007744|PDB:6OQ5 |
| Chain | Residue | Details |
| A | HIS214 | |
| B | HIS214 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by autolysis => ECO:0000269|PubMed:15632438 |
| Chain | Residue | Details |
| A | MET0 | |
| B | MET0 |
