9BGF
Structure of human GlcNAc-1-phosphotransferase complexed with the donor substrate UDP-GlcNAc
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000139 | cellular_component | Golgi membrane |
| A | 0003976 | molecular_function | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0007040 | biological_process | lysosome organization |
| A | 0009306 | biological_process | protein secretion |
| A | 0015031 | biological_process | protein transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016256 | biological_process | N-glycan processing to lysosome |
| A | 0016740 | molecular_function | transferase activity |
| A | 0033299 | biological_process | secretion of lysosomal enzymes |
| A | 0046835 | biological_process | carbohydrate phosphorylation |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051649 | biological_process | establishment of localization in cell |
| B | 0000139 | cellular_component | Golgi membrane |
| B | 0003976 | molecular_function | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005794 | cellular_component | Golgi apparatus |
| B | 0007040 | biological_process | lysosome organization |
| B | 0009306 | biological_process | protein secretion |
| B | 0015031 | biological_process | protein transport |
| B | 0016020 | cellular_component | membrane |
| B | 0016256 | biological_process | N-glycan processing to lysosome |
| B | 0016740 | molecular_function | transferase activity |
| B | 0033299 | biological_process | secretion of lysosomal enzymes |
| B | 0046835 | biological_process | carbohydrate phosphorylation |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051649 | biological_process | establishment of localization in cell |
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DTDQSGVLSdrEI |
| Chain | Residue | Details |
| A | ASP1018-ILE1030 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00525 |
| Chain | Residue | Details |
| A | ASP449 | |
| B | ASP516 | |
| B | ASP531 | |
| B | ASP534 | |
| A | ASP464 | |
| A | ASP467 | |
| A | ASP516 | |
| A | ASP531 | |
| A | ASP534 | |
| B | ASP449 | |
| B | ASP464 | |
| B | ASP467 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448 |
| Chain | Residue | Details |
| A | ASP1018 | |
| A | ASP1020 | |
| A | SER1022 | |
| A | GLU1029 | |
| B | ASP1018 | |
| B | ASP1020 | |
| B | SER1022 | |
| B | GLU1029 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by MBTPS1 |
| Chain | Residue | Details |
| A | ARG928 | |
| B | ARG928 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 20 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN83 | |
| A | ASN1129 | |
| B | ASN83 | |
| B | ASN114 | |
| B | ASN148 | |
| B | ASN179 | |
| B | ASN250 | |
| B | ASN614 | |
| B | ASN729 | |
| B | ASN829 | |
| B | ASN1009 | |
| A | ASN114 | |
| B | ASN1129 | |
| A | ASN148 | |
| A | ASN179 | |
| A | ASN250 | |
| A | ASN614 | |
| A | ASN729 | |
| A | ASN829 | |
| A | ASN1009 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218 |
| Chain | Residue | Details |
| A | ASN699 | |
| B | ASN699 |
