Functional Information from PROSITE/UniProt
| site_id | PS00170 |
| Number of Residues | 18 |
| Details | CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YkgSsFHRIIpgFMcQGG |
| Chain | Residue | Details |
| C | TYR48-GLY65 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: N-acetylmethionine => ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378, ECO:0007744|PubMed:25944712 |
| Chain | Residue | Details |
| C | MET1 | |
| D | MET1 | |
| A | ALA59 | |
| A | ASN116 | |
| B | GLY10 | |
| B | VAL29 | |
| B | ALA59 | |
| B | ASN116 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: N-acetylvaline; partial; in Peptidyl-prolyl cis-trans isomerase A, N-terminally processed => ECO:0000269|PubMed:25489052, ECO:0000269|Ref.12, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:25944712 |
| Chain | Residue | Details |
| C | VAL2 | |
| D | VAL2 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| C | LYS28 | |
| C | LYS82 | |
| D | LYS28 | |
| D | LYS82 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| C | LYS44 | |
| C | LYS76 | |
| C | LYS131 | |
| D | LYS44 | |
| D | LYS76 | |
| D | LYS131 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| C | SER77 | |
| D | SER77 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231 |
| Chain | Residue | Details |
| C | THR93 | |
| D | THR93 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:20364129, ECO:0000269|PubMed:25678563, ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| C | LYS125 | |
| D | LYS125 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P17742 |
| Chain | Residue | Details |
| C | LYS133 | |
| D | LYS133 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| C | ASN108 | |
| D | ASN108 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate |
| Chain | Residue | Details |
| C | LYS28 | |
| D | LYS28 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| C | LYS82 | |
| D | LYS82 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 7 |
| Details | M-CSA 189 |
| Chain | Residue | Details |
| C | ARG55 | electrostatic stabiliser, hydrogen bond donor, steric role |
| C | PHE60 | polar/non-polar interaction, steric role |
| C | GLN63 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| C | ASN102 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| C | PHE113 | polar/non-polar interaction, steric role |
| C | LEU122 | polar/non-polar interaction, steric role |
| C | HIS126 | polar/non-polar interaction, steric role |
| site_id | MCSA2 |
| Number of Residues | 7 |
| Details | M-CSA 189 |
| Chain | Residue | Details |
| D | ARG55 | electrostatic stabiliser, hydrogen bond donor, steric role |
| D | PHE60 | polar/non-polar interaction, steric role |
| D | GLN63 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| D | ASN102 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| D | PHE113 | polar/non-polar interaction, steric role |
| D | LEU122 | polar/non-polar interaction, steric role |
| D | HIS126 | polar/non-polar interaction, steric role |
