9BDD

Cryo-EM Structure of Non-Cognate Substrate Bound in the Entry Site (ES) of Human Mitochondrial Transcription Elongation Complex

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0000175	molecular_function	3'-5'-RNA exonuclease activity
E	0000428	cellular_component	DNA-directed RNA polymerase complex
E	0001018	molecular_function	mitochondrial promoter sequence-specific DNA binding
E	0001054	molecular_function	RNA polymerase I activity
E	0001055	molecular_function	RNA polymerase II activity
E	0001056	molecular_function	RNA polymerase III activity
E	0001057	molecular_function	RNA polymerase IV activity
E	0001058	molecular_function	RNA polymerase V activity
E	0001059	biological_process	transcription by RNA polymerase IV
E	0001060	biological_process	transcription by RNA polymerase V
E	0001065	molecular_function	mitochondrial single subunit type RNA polymerase activity
E	0001066	molecular_function	plastid single subunit type RNA polymerase activity
E	0003723	molecular_function	RNA binding
E	0003896	molecular_function	DNA primase activity
E	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
E	0005515	molecular_function	protein binding
E	0005739	cellular_component	mitochondrion
E	0005759	cellular_component	mitochondrial matrix
E	0006269	biological_process	DNA replication, synthesis of primer
E	0006360	biological_process	transcription by RNA polymerase I
E	0006366	biological_process	transcription by RNA polymerase II
E	0006383	biological_process	transcription by RNA polymerase III
E	0006390	biological_process	mitochondrial transcription
E	0006391	biological_process	transcription initiation at mitochondrial promoter
E	0016779	molecular_function	nucleotidyltransferase activity
E	0032991	cellular_component	protein-containing complex
E	0034062	molecular_function	5'-3' RNA polymerase activity
E	0034245	cellular_component	mitochondrial DNA-directed RNA polymerase complex
E	0042645	cellular_component	mitochondrial nucleoid
E	0042793	biological_process	plastid transcription
E	0043565	molecular_function	sequence-specific DNA binding

Functional Information from PROSITE/UniProt

site_id	PS00489
Number of Residues	15
Details	RNA_POL_PHAGE_2 Bacteriophage-type RNA polymerase family active site signature 2. ItRkvvKqtVMTvvY

Chain	Residue	Details
E	ILE985-TYR999

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site_id	PS00900
Number of Residues	12
Details	RNA_POL_PHAGE_1 Bacteriophage-type RNA polymerase family active site signature 1. PVhqDGSCNGLQ

Chain	Residue	Details
E	PRO918-GLN929

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE: ACT_SITE => ECO:0000250

Chain	Residue	Details
E	ASP922
E	LYS991
E	ASP1151

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